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Expression of Oscillin in Mouse Testis

Lee YH, Choi KW, Kim JW, Kim MK, Nah H, Gye MC

  • KMID: 2298827
  • Korean J Androl.
  • 1998 Dec;16(2):129-134.
PURPOSE: To verify the expression of the egg activator oscillin in mouse testis and adult organs. MATERIALS AND METHODS: Genomic PCR using primers for oscillin was conducted to confirm that the...
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Expression of Aquaporin-8 in Placenta of Preeclampsia

Ha MS, Hwang TG, Lee SK, Lee IH, Hong SH, Park YJ, Jeong EH, Kim HS

  • KMID: 2272459
  • Korean J Obstet Gynecol.
  • 2004 Dec;47(12):2308-2312.
OBJECTIVE: This study was to determine whether aquaporin-8, which plays a role as a transcellular water channel, is expressed in human placenta, and to compare the degree of its expression...
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Gene Expression Analysis of Murine Primary Microglia Stimulated with LPS using Microarray

Park JE, Jung D, Han HS

  • KMID: 1626984
  • J Korean Neurol Assoc.
  • 2005 Feb;23(1):77-87.
BACKGROUND: Since heightened microglial activation was shown to play a role in the pathogenesis of many brain disorders, understanding the molecular mechanisms of microglial activation may lead to new treatment...
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Microarray Analysis of Oxygen-Glucose-Deprivation Induced Gene Expression in Cultured Astrocytes

Joo DH, Han HS, Park JS

  • KMID: 2071635
  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):263-271.
Since astrocytes were shown to play a central role in maintaining neuronal viability both under normal conditions and during stress such as ischemia, studies of the astrocytic response to stress...
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Systemic injection of lidocaine induce expression of c-fos mRNA and protein in adult rat brain

Chae HJ, Kang JS, Cho SB, Jin BG, Won SJ, Gwan BJ, Kim HR

  • KMID: 1917072
  • Korean J Physiol Pharmacol.
  • 1999 Feb;3(1):69-74.
Both direct and indirect environmental stress to brain were increase the expression of transcription factor c-fos in various populations of neurons. In this study, we examined whether the intraperitoneal injections of lidocaine at...
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Renal Adaptive Responses of Na+-K+-APTase Subunit Isoforms to Chronic Hypokalemia

Ahn KY, Kim SC, Moon B, Kim KK, Kim BY

  • KMID: 1530104
  • Korean J Anat.
  • 1998 Jun;31(3):405-418.
Chronic hypokalemia alters Na+-K+-ATPase gene expression in several tissues. While it is established that Na+-K+-ATPase activity and alpha1 and beta1 subunit protein levels increase during K depletion in the outer...
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Expression of GnRH and GnRH-receptor mRNAs in the Human Placenta

Kim MO, Koh PO, Cho GJ, Kim HS, Lee JH, Kim JH, Paik WY, Choi WS

  • KMID: 2283079
  • Korean J Phys Anthropol.
  • 1998 Jun;11(1):165-175.
Placental GnRH is one of the potential paracrine regulator of hCG secretion from the trophoblasts during pregnancy. However, this paracrine function is not clearly confirmed. The present study was designed...
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Inhibitory Effects of Structurally Different Neuromuscular Blockers on the Serotonin Type 3 Receptor Expressed in Xenopus Oocytes

Min KT, Nam YT, Oh KM, Yang J

BACKGROUND: The serotonin type 3 receptors are diffusely distributed in both the central and the peripheral nervous system. Physiological and pathophysiological processes thought to be mediated by this receptor include...
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Expression and Localization of General Transcription Factor IIA Gene in Hypokalemic Rat

Lee CB, Lee YC, Cho HJ, Lee SE, Bae CS, Kim BY, Park SS, Ahn KY

  • KMID: 2092915
  • Korean J Anat.
  • 2008 Mar;41(1):29-37.
Potassium balance in chronic hypokalemia is regulated by ion channels, ion transporters, and various related genes. We isolated general transcription factor IIA (GTF IIA) gene using a DNA chip microassay,...
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Quercetin Inhibits alpha3beta4 Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes

Lee BH, Hwang SH, Choi SH, Shin TJ, Kang J, Lee SM, Nah SY

  • KMID: 2389104
  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):17-22.
Quercetin mainly exists in the skin of colored fruits and vegetables as one of flavonoids. Recent studies show that quercetin, like other flavonoids, has diverse pharmacological actions. However, relatively little...
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Functional abnormalities of HERG mutations in long QT syndrome 2 (LQT2)

Hiraoka M

  • KMID: 1607075
  • Korean J Physiol Pharmacol.
  • 2001 Oct;5(5):367-371.
The chromosome 7-linked long QT syndrome (LQT2) is caused by mutations in the human ether-a-go-go-related gene (HERG) that encodes the rapidly activating delayed rectifier K+ current, IKr, in cardiac myocytes. Different types of...
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Expression of CDK inhibitor (CDI) p57 and bcl-2 mRNA during follicular development and follicular atresia in the rat ovary

Cho GJ, Koh PO, Kwak SD, Kim MO, Lee BH, Choi WS, Baik SH

  • KMID: 1530096
  • Korean J Anat.
  • 1998 Jun;31(3):361-370.
In mammals, the ovary proceeds follicular development and atresia during the reproductive cycle. Follicular atresia occurs through apoptosis, programmed cell death (PCD) which is mediated by gene controlling apoptosis and...
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Effects of Protopanaxatriol-Ginsenoside Metabolites on Rat N-Methyl-D-Aspartic Acid Receptor-Mediated Ion Currents

Shin TJ, Hwang SH, Choi SH, Lee BH, Kang J, Kim HJ, Zukin RS, Rhim H, Nah SY

Ginsenosides are low molecular weight glycosides found in ginseng that exhibit neuroprotective effects through inhibition of N-methyl-D-aspartic acid (NMDA) receptor channel activity. Ginsenosides, like other natural compounds, are metabolized by...
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Resveratrol Inhibits GABAC rho Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes

Lee BH, Choi SH, Hwang SH, Kim HJ, Lee JH, Nah SY

Resveratrol is a phytoalexin found in grapes, red wine, and berries. Resveratrol has been known to have many beneficial health effects, such as anti-cancer, neuroprotective, anti-inflammatory, and life-prolonging effects. However,...
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Inhibitory Effects of Ginsenoside Metabolites, Compound K and Protopanaxatriol, on GABAC Receptor-Mediated Ion Currents

Lee BH, Hwang SH, Choi SH, Kim HJ, Lee JH, Lee SM, Ahn YG, Nah SY

Ginsenosides, one of the active ingredients of Panax ginseng, show various pharmacological and physiological effects, and they are converted into compound K (CK) or protopanaxatriol (M4) by intestinal microorganisms. CK...
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Inhibitory Effects of Quercetin on Muscle-type of Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes

Lee BH, Shin TJ, Hwang SH, Choi SH, Kang J, Kim HJ, Park CW, Lee SH, Nah SY

The flavonoid quercetin is a low molecular weight compound generally found in apple, gingko, tomato, onion and other red-colored fruits and vegetables. Like other flavonoids, quercetin has diverse pharmacological actions....
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Co-localization and interaction of organic anion transporter 1 with caveolin-2 in rat kidney

Kwak JO, Kim HW, Oh KJ, Kim DS, Han KO, Cha SH

  • KMID: 1056233
  • Exp Mol Med.
  • 2005 Jun;37(3):204-212.
The organic anion transporters (OAT) have recently been identified. Although the some transport properties of OATs in the kidney have been verified, the regulatory mechanisms for OAT's functions are still...
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