- New Synthetic Surfactants for Neonates
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Kim YD
- KMID: 2188307
- J Korean Soc Neonatol.
- 2012 Nov;19(4):184-194.
- doi: 10.5385/jksn.2012.19.4.184
The benefits of exogenous synthetic or animal-derived natural surfactants for treatment of respiratory distress syndrome (RDS) are well established. Although synthetic surfactants have potential safety advantages over animal-derived products, they... -
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- Exogenous pulmonary surfactant replacement therapy in severe respiratory distress syndrome: randomized controlled clinical trial between surfactant (surfacten & survanta)-treated group and control group
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Jun YH, Chang YS, Son DW, Chang YP, Kim BI, Choi JH, Yun CK
- KMID: 1691531
- Korean J Perinatol.
- 1993 Dec;4(4):455-472.
No abstract available. -
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- Surfactant preparations for preterm infants with respiratory distress syndrome: past, present, and future
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Jeon GW
- KMID: 2451963
- Korean J Pediatr.
- 2019 May;62(5):155-161.
- doi: 10.3345/kjp.2018.07185
Following the first successful trial of surfactant replacement therapy for preterm infants with respiratory distress syndrome (RDS) by Fujiwara in 1980, several animal-derived natural surfactants and synthetic surfactants have been... -
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- The use of artificial pulmonary surfactant in neonatal respiratory distress
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Choi YS
- KMID: 2194965
- J Korean Med Assoc.
- 2015 Apr;58(4):330-335.
- doi: 10.5124/jkma.2015.58.4.330
Pulmonary surfactant instillation is the treatment of choice in neonatal respiratory distress syndrome. The development of artificial surfactant has three decades of history. Animal-derived artificial surfactant is used in most... -
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- Genetic risk factors associated with respiratory distress syndrome
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Jo HS
- KMID: 2284679
- Korean J Pediatr.
- 2014 Apr;57(4):157-163.
- doi: 10.3345/kjp.2014.57.4.157
Respiratory distress syndrome (RDS) among preterm infants is typically due to a quantitative deficiency of pulmonary surfactant. Aside from the degree of prematurity, diverse environmental and genetic factors can affect... -
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- Lysis of RBc Membrane and Type II Alveolar Epithelial Cell Toxicity by Various Artificial Pulmonary Surfactants Used in Korea
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Park EA, Lee KE, Kim GH
- KMID: 1566089
- J Korean Soc Neonatol.
- 1998 Nov;5(2):151-157.
PURPOSE: Surfactant replacement therapy is now recognized as a life saving and safe intervention in small premature infants with respiratory distress syndrome. The incidence of pulmonary hemorrhage is increased in... -
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- A case of acute respiratory distress syndrome due to maternal blood aspiration
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Park JH, Kim CS, Lee SL
- KMID: 1980199
- Korean J Perinatol.
- 2009 Mar;20(1):74-77.
Blood was known as a potent inhibitor of pulmonary surfactant, and maternal blood aspiration is a rare cause of respiratory distress syndrome in neonates. We experienced a neonate with a... -
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- New Medical Drugs for Care of Premature Infants
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Bae CW
- KMID: 1469553
- J Korean Med Assoc.
- 2009 Feb;52(2):191-198.
- doi: 10.5124/jkma.2009.52.2.191
Several advances in premature and neonatal care, such as, development in new drugs and equipments, and improvement of medical skills, have also undoubtedly contributed to the reductions in morbidity and... -
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- Comparison of in vitro Surface Physical Properties of Four Artificial Exogenous Pulmonary Surfactant Preparations
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Bae CW, Choi YM, Lee SC, Kang JH, Kim KL, Hahm KS
- KMID: 2335435
- J Korean Pediatr Soc.
- 1999 Sep;42(9):1215-1223.
PURPOSE: We conducted this study to compare the surface physical properties of four commercial preparations of artificial exogenous pulmonary surfactants in vitro which have been used in both the prevention... -
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- Effects of Two Different Surfactants on RBC Membrane and Type II Alveolar Epithelial Cell in Vitro
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Park EA, Kim GH
- KMID: 1946321
- J Korean Pediatr Soc.
- 1999 Jan;42(1):32-39.
PURPOSE: Respiratory distress syndrome(RDS) is a major cause of death in premature babies. For the treatment of RDS, various artificial pulmonary surfactants have been used. The incidence of pulmonary hemorrhage... -
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- Surfactant Therapy in Severe Meconium Aspiration Syndrome
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Lee SL, Kim CS
- KMID: 2312944
- Neonatal Med.
- 2013 Aug;20(3):318-322.
Meconium is a strong inactivator of pulmonary surfactant. The deficiency of surfactant or surfactant dysfunction may contribute to respiratory failure in a wide group of disorders, including meconium aspiration syndrome... -
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- History of Pulmonary Surfactant Replacement Therapy for Neonatal Respiratory Distress Syndrome in Korea
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Bae CW, Kim CY, Chung SH, Choi YS
- KMID: 2450454
- J Korean Med Sci.
- 2019 Jul;34(25):e175.
- doi: 10.3346/jkms.2019.34.e175
Neonatal respiratory distress syndrome (RDS) is a disease that is unique to newborn infants. It is caused by a deficiency of pulmonary surfactant (PS), which is usually ready to be... -
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- Exogenous Surfactant Therapy in Neonates with Respiratory Failure Due to Pulmonary Hemorrhage
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Choi HJ, Sin YH, Kim SM
- KMID: 2280840
- Korean J Perinatol.
- 2011 Dec;22(4):319-328.
PURPOSE: The study assessed the effect of exogenous surfactant on oxygen and ventilator requirements and long-term prognosis of neonates with respiratory deterioration due to pulmonary hemorrhage. METHODS: From March 2007 to... -
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- Comparisons of Physical and Biological Activities between Newfactan(R), Surfacten(R) and Exosurf(R)
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Lee DW, Park MS, Jeon JH, Choi EN, Park KI, Namgung R, Lee C
- KMID: 2188541
- J Korean Soc Neonatol.
- 2006 May;13(1):1-8.
PURPOSE: Neonatal respiratory distress syndrome (RDS) is caused by the deficiency of pulmonary surfactants in the newborn. We aim to determine and compare the physical and biological activities of the... -
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- The Effects of Surfactant Therapy using High Frequency Jet Ventilation on Lung Lavaged Dogs
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Kwoen OK
- KMID: 2239271
- Korean J Anesthesiol.
- 1991 Jun;24(3):465-470.
- doi: 10.4097/kjae.1991.24.3.465
The effects of exogenous surfactant replacement therapy using high frequency jet ventilation (HFJV) on arterial blood gases changes, pulmonary and hemodynamic variables were observed in lungs lavaged dogs with saline.... -
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- A Case of Neonatal Massive Pulmonary Heomorrhage Treated With Pulmonary Surfactant Replacement
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Cho YJ, Lee HJ, Lee SL
- KMID: 2099004
- J Korean Soc Neonatol.
- 1999 Nov;6(2):258-262.
Massive pulmonary hemorrhage in neonates is defined as an acute onset of severe endotracheal bleeding with an acute drop in hematocrit and the development of multilobar infiltrates on chest radiograph.... -
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- Purification and Analysis of Amino Acid Sequences of Pulmonary Surfactant Proteins
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Bae CW, Choi YM
- KMID: 2188741
- J Korean Soc Neonatol.
- 1999 May;6(1):1-7.
PURPOSE: For the synthesis of surfactant protein(SP) peptides and production of next generation artificial pulmonary surfactant(PS), we have isolated SP-B, C from bovine PS, and studied the biochemical properties and amino... -
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- Effect of Nebulized Bovine Surfactant for Experimental Otitis Media with Effusion
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Jang CH, Cho YB, Oh SE, Choi JU, Park H, Choi CH
- KMID: 2278638
- Clin Exp Otorhinolaryngol.
- 2010 Mar;3(1):13-17.
OBJECTIVES: In this study, we evaluated the efficacy of nebulized bovine pulmonary surfactant on experimentally induced otitis media with effusion (OME) in guinea pigs. METHODS: Twenty guinea pigs were divided into... -
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- Changes in dead space/tidal volume ratio and pulmonary mechanics after surfactant replacement therapy in respiratory distress syndrome of the newborn infants
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Chung EH, Ko SY, Kim IY, Chang YS, Park WS
- KMID: 1066494
- J Korean Med Sci.
- 2001 Feb;16(1):51-56.
- doi: 10.3346/jkms.2001.16.1.51
This study was performed to elucidate the mechanism of improved oxygenation after surfactant replacement therapy in respiratory distress syndrome (RDS) of the newborn infants. In 26 newborns with RDS, end... -
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- In vitro inhibition of biophysical surface properties and change in ultrastructures of exogenous pulmonary surfactant by albumin or fibrinogen
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Park J, Bae CW, Choi YM
- KMID: 1064958
- J Korean Med Sci.
- 1998 Apr;13(2):123-130.
- doi: 10.3346/jkms.1998.13.2.123
In order to observe the effects of serum albumin and fibrinogen on biophysical surface properties and the morphology of pulmonary surfactant in vitro, we measured the surface adsorption rate,... -
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