J Korean Soc Neonatol.  1999 Nov;6(2):258-262.

A Case of Neonatal Massive Pulmonary Heomorrhage Treated With Pulmonary Surfactant Replacement

• Cho YJ
• Lee HJ
• Lee SL

Abstract

Massive pulmonary hemorrhage in neonates is defined as an acute onset of severe endotracheal bleeding with an acute drop in hematocrit and the development of multilobar infiltrates on chest radiograph. It results from a wide etiologic spectrum and is a potentially life-threatening disorder. We experienced a case of massive pulmonary hemorrhage in 1-day-old male who was small for gestational age and whose mother was complicated with severe pregnancy induced hypertension. He was hospitalized due to tachypnea and poor feeding 24 hours after birth, and bright bloody fluid was continually suctioned from the trachea 4 hours after admission. Packed red blood cell and fresh frozen plasma was transfused. Respiratory failure was refractory to conventional mechanical ventilation. He received surfactant replacement therapy 12 hours after pulmonary hemorrhage, and subsequently chest x-ray findings and oxygenation index improved. He was discharged on the 20th day of life without any problem.

Keyword

Pulmonary hemorrhage; Pulmonary surfactant; Neonate

MeSH Terms

Erythrocytes
Female
Gestational Age
Hematocrit
Hemorrhage
Humans
Hypertension, Pregnancy-Induced
Infant, Newborn
Male
Mothers
Oxygen
Parturition
Plasma
Pregnancy
Pulmonary Surfactants*
Radiography, Thoracic
Respiration, Artificial
Respiratory Insufficiency
Suction
Tachypnea
Thorax
Trachea
Oxygen
Pulmonary Surfactants