J Korean Soc Neonatol.
1999 Nov;6(2):258-262.
A Case of Neonatal Massive Pulmonary Heomorrhage Treated With Pulmonary Surfactant Replacement
- Affiliations
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- 1Department of Pediatrics, Keimyung University, School of Medicine, Taegu, Korea.
- 2Department of Diagnostic Radiology, Keimyung University, School of Medicine, Taegu, Korea.
Abstract
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Massive pulmonary hemorrhage in neonates is defined as an acute onset of severe endotracheal bleeding with an acute drop
in hematocrit and the development of multilobar infiltrates on chest radiograph. It results from a wide etiologic spectrum
and is a potentially life-threatening disorder. We experienced a case of massive pulmonary hemorrhage in 1-day-old male
who was small for gestational age and whose mother was complicated with severe pregnancy induced hypertension. He was
hospitalized due to tachypnea and poor feeding 24 hours after birth, and bright bloody fluid was continually suctioned
from the trachea 4 hours after admission. Packed red blood cell and fresh frozen plasma was transfused. Respiratory failure
was refractory to conventional mechanical ventilation. He received surfactant replacement therapy 12 hours after pulmonary
hemorrhage, and subsequently chest x-ray findings and oxygenation index improved. He was discharged on the 20th day of life
without any problem.