- A Case of Erythropoietic Protoporphyria Screened by RBC Fluorescence Microscopy
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Heo EP, Kim SE, Lee WS, Yoon TJ, Kim TH
- KMID: 2146443
- Korean J Dermatol.
- 2002 Jan;40(1):63-67.
Erythropoietic protoporphyria (EPP), caused by decreased activity of the enzyme ferrochelatase, is characterized clinically by burning photosensitivity beginning from childhood, and chemically by excessive amounts of red blood cell protoporphyrins.... -
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- Protoporphyrin IX Synthesis Induced by 5-aminolevulinic Acid and Its Esters in Normal Mouse Skin
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Kim HS, Na EY, Yun SJ, Kim SJ, Lee SC, Won YH, Park HR, Lee JB
- KMID: 2247815
- Korean J Dermatol.
- 2009 Jun;47(6):683-689.
BACKGROUND: Photodynamic therapy with using 5-aminolevulinic acid (ALA) is a good noninvasive treatment modality that can treat several cutaneous diseases. Yet hydrophilic ALA is not able to easily penetrate the... -
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- Effectiveness of zinc protoporphyrin/heme ratio for screening iron deficiency in preschool-aged children
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Yu KH
- KMID: 2313497
- Nutr Res Pract.
- 2011 Feb;5(1):40-45.
Hemoglobin and zinc protoporphyrin (ZPP) tests are commonly used to screen for iron deficiency, but little research has been done to systematically evaluate the sensitivity and specificity of these two... -
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- Photodynamic therapy using topically applied 5-aminolevulinic acid for treatment of cervical cancer
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Youn MH, Cho HC, Ahn JC, Park CH, Park JW
- KMID: 2037510
- Korean J Obstet Gynecol.
- 2010 Dec;53(12):1092-1099.
- doi: 10.5468/kjog.2010.53.12.1092
OBJECTIVE: The purpose of this study was to investigate the treatment effects of a topical application of 5-aminolevulinic acid (5-ALA) for photodynamic therapy (PDT) to treat cervical cancer. METHODS: We first... -
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- Occupational Health Management in the Lead Industry: The Korean Experience
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Lee BK
- KMID: 2317005
- Saf Health Work.
- 2011 Jun;2(2):87-96.
In 1967, the problem of occupational lead exposure came to public attention in Korea. Since then, regular progress has been made in lowering workplace lead exposures, instituting new workplace controls,... -
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- Heme Oxygenase-1 Induced by Aprotinin Inhibits Vascular Smooth Muscle Cell Proliferation Through Cell Cycle Arrest in Hypertensive Rats
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Choi HC, Lee KY, Lee DH, Kang YJ
- KMID: 2071686
- Korean J Physiol Pharmacol.
- 2009 Aug;13(4):309-313.
- doi: 10.4196/kjpp.2009.13.4.309
Spontaneous hypertensive rats (SHR) are an established model of genetic hypertension. Vascular smooth muscle cells (VSMC) from SHR proliferate faster than those of control rats (Wistar-Kyoto rats; WKY). We tested... -
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- Aprotinin Inhibits Vascular Smooth Muscle Cell Inflammation and Proliferation via Induction of HO-1
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Lee DH, Choi HC, Lee KY, Kang YJ
- KMID: 2071661
- Korean J Physiol Pharmacol.
- 2009 Apr;13(2):123-129.
- doi: 10.4196/kjpp.2009.13.2.123
Aprotinin is used clinically in cardiopulmonary bypass surgery to reduce transfusion requirements and the inflammatory response. The mechanism of action for the anti-inflammatory effects of aprotinin is still unclear.... -
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- A Case of Lead Poisoning by Ingesting Herbal Pills Tainted by Lead during the Manufacturing Process
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Shin YH, Son JS, Kim YW, Chae CH, Kim JH, Kim CW, Lee JH
- KMID: 2028508
- Korean J Occup Environ Med.
- 2010 Sep;22(3):271-277.
BACKGROUND: This is a case report of lead poisoning after herbal pill ingestion. We report this case here as a reminder that contamination during the manufacturing process is an important... -
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- Assessment of Iron Parameters in Children with Acute Infectious Disease
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Hwang HY, Kim JS, Lee JH, Hong YR, Park JS
- KMID: 2049274
- Clin Pediatr Hematol Oncol.
- 2012 Oct;19(2):72-78.
BACKGROUND: As some parameters reflecting iron status were known to change with infection or inflammation, we examined the changes of these parameters in children with minor illnesses. METHODS: Hematologic tests were... -
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- Protective Effect of Heme Oxygenase-1 on High Glucose-Induced Pancreatic beta-Cell Injury
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Lee EM, Lee YE, Lee E, Ryu GR, Ko SH, Moon SD, Song KH, Ahn YB
- KMID: 1857502
- Diabetes Metab J.
- 2011 Oct;35(5):469-479.
- doi: 10.4093/dmj.2011.35.5.469
BACKGROUND: Glucose toxicity that is caused by chronic exposure to a high glucose concentration leads to islet dysfunction and induces apoptosis in pancreatic beta-cells. Heme oxygenase-1 (HO-1) has been identified... -
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- Effect of quercetin on the production of nitric oxide in murine macrophages stimulated with lipopolysaccharide from Prevotella intermedia
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Cho YJ, Kim SJ
- KMID: 2027815
- J Periodontal Implant Sci.
- 2013 Aug;43(4):191-197.
- doi: 10.5051/jpis.2013.43.4.191
PURPOSE: Nitric oxide (NO) is a short-lived bioactive molecule that is known to play an important role in the pathogenesis of periodontal disease. In the current study, we investigated the... -
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- Cholestyramine resin for erythropoietic protoporphyria with severe hepatic disease: a case report
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Yoo DJ, Lee HC, Yu E, Jin YJ, Shim JH, Kim KM, Lim YS, Chung YH, Lee YS, Suh DJ
- KMID: 1782225
- Korean J Hepatol.
- 2010 Mar;16(1):83-88.
- doi: 10.3350/kjhep.2010.16.1.83
Erythropoietic protoporphyria (EPP) is a rare disorder of heme biosynthesis caused by mutations in the gene encoding the enzyme ferrochelatase. In EPP, deficient ferrochelatase activity leads to the excessive production... -
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- Effects of Heme Oxygenase-1 Inducer and Inhibitor on Experimental Autoimmune Uveoretinitis
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Jang JU, Lee SH, Choi CU, Bahk SC, Chung HT, Yang YS
- KMID: 754643
- Korean J Ophthalmol.
- 2007 Dec;21(4):238-243.
- doi: 10.3341/kjo.2007.21.4.238
PURPOSE: Experimental autoimmune uveoretinitis (EAU) is an animal model of posterior uveitis and heme oxygenase-1 (HO-1) is a well-known anti-oxidant factor. However, there is no report a protective role... -
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- Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells
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Pae HO, Jeong GS, Jeong SO, Kim HS, Kim SA, Kim YC, Yoo SJ, Kim HD, Chung HT
- KMID: 1047077
- Exp Mol Med.
- 2007 Jun;39(3):267-277.
In vascular smooth muscle cells (VSMCs), induction of the heme oxygenase-1 (HO-1) confers vascular protection against cellular proliferation mainly via its up-regulation of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1) that is... -
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