- The Proteomics Approach to Find Biomarkers in Gastric Cancer
-
Ryu JW, Kim HJ, Lee YS, Myong NH, Hwang CH, Lee GS, Yom HC
- KMID: 648901
- J Korean Med Sci.
- 2003 Aug;18(4):505-509.
- doi: 10.3346/jkms.2003.18.4.505
Gastric cancer is a very serious disease and is naturally resistant to many anticancer drugs. To reduce the mortality and improve the effectiveness of therapy, many studies have tried to... -
- CITED
-
- Close
- SHARE
-
- Close
- Evaluation and comparison of native and recombinant LipL21 protein-based ELISAs for diagnosis of bovine leptospirosis
-
Joseph S, Thomas N, Thangapandian E, Singh VP, Verma R, Srivastava SK
- KMID: 1365009
- J Vet Sci.
- 2012 Mar;13(1):99-101.
- doi: 10.4142/jvs.2012.13.1.99
A 21-kDa leptospiral lipoprotein (LipL21) was evaluated for its diagnostic potential to detect bovine leptospirosis by ELISA. Both native LipL21 (nLipL21) and recombinant LipL21 (rLipL21) proteins were tested and compared... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of CD99 in Pleomorphic Carcinomas of the Lung
-
Yoo SH, Han J, Kim TJ, Chung DH
- KMID: 1781724
- J Korean Med Sci.
- 2005 Feb;20(1):50-55.
- doi: 10.3346/jkms.2005.20.1.50
Pleomorphic carcinoma of the lung (PCL) is characterized by a mixture of sarcomatoid and carcinoma components, and a poor prognosis. However, no immunophenotype of tumor markers has been characterized in... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression and localization of human papillomavirus type 16 E6 and E7 open reading frame proteins in human epidermal keratinocyte
-
Kim KH, Yoon DJ, Moon YA, Kim YS
- KMID: 1381212
- Yonsei Med J.
- 1994 Mar;35(1):1-9.
- doi: 10.3349/ymj.1994.35.1.1
Over 60 different types of human papillomavirus (HPV) have been identified, and they are classified into high and low risk groups based on the risk for malignant progression of HPV... -
- CITED
-
- Close
- SHARE
-
- Close
- Fas-mediated apoptosis and expression of related genes in human malignant hematopoietic cells
-
Kim KM, Lee KH, Hong YS, Park HY
- KMID: 755108
- Exp Mol Med.
- 2000 Dec;32(4):246-254.
Fas transduces apoptotic signals upon cross-linking with the Fas ligand (FasL), which is experimentally replaced by agonistic anti-Fas monoclonal antibodies (mAb). Of eight human malignant hematopoietic cell lines... -
- CITED
-
- Close
- SHARE
-
- Close
- Suppression of NF-kappaB activation in normal T cells by supernatant fluid from human renal cell carcinomas
-
Kim HJ, Park JK, Kim YG
- KMID: 646309
- J Korean Med Sci.
- 1999 Jun;14(3):299-303.
- doi: 10.3346/jkms.1999.14.3.299
T lymphocytes from patients with renal cell carcinoma (RCC) show reduced immune function and impaired activation of the transcription factor, NF-kappaB. We determined the mechanism of NF-kappaB suppression in T... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of Cell Cycle Regulators During Smooth Muscle Cell Proliferation After Balloon Catheter Injury of Rat Artery
-
Chung JK, Lee T, Jung IM, Kim YK, Min SK, Suh JW, Kim SJ
- KMID: 1786807
- J Korean Med Sci.
- 2004 Jun;19(3):327-332.
- doi: 10.3346/jkms.2004.19.3.327
Intimal hyperplasia is defined as the abnormal migration and proliferation of vascular smooth muscle cells (VSMCs) with deposition of extracellular matrix. However, the cell cycle regulatory mechanisms of injury-induced VSMC... -
- CITED
-
- Close
- SHARE
-
- Close
- Prognostic significance of E-cadherin/catenin complex expression in gastric cancer
-
Joo YE, Park CS, Kim HS, Choi SK, Rew JS, Kim SJ
- KMID: 2157546
- J Korean Med Sci.
- 2000 Dec;15(6):655-666.
- doi: 10.3346/jkms.2000.15.6.655
Abnormal expression of E-cadherin/catenin complex in cancer has been associated with poor differentiation and acquisition of invasiveness, suggesting a possible role of this protein as an invasion suppressor. In this... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of allyl sulfur compounds and garlic extract on the expression of Bcl-2, Bax, and p53 in non small cell lung cancer cell lines
-
Hong YS, Ham YA, Choi JH, Kim JG
- KMID: 755076
- Exp Mol Med.
- 2000 Sep;32(3):127-134.
Allyl sulfur compounds play a major role in the chemoprevention against carcinogenesis. The present study compared the antiproliferative effects of diallyl sulfide (DAS), diallyl disulfide (DADS) and garlic... -
- CITED
-
- Close
- SHARE
-
- Close
- Microarray Analysis of Thyroid Stimulating Hormone, Insulin-Like Growth Factor-1, and Insulin-Induced Gene Expression in FRTL-5 Thyroid Cells
-
Lee YJ, Park DJ, Shin CS, Park KS, Kim SY, Lee HK, Park YJ, Cho BY
- KMID: 1713298
- J Korean Med Sci.
- 2007 Oct;22(5):883-890.
- doi: 10.3346/jkms.2007.22.5.883
To determine which genes are regulated by thyroid stimulating hormone (thyrotropin, TSH), insulin and insulin-like growth factor-1 (IGF-1) in the rat thyroid, we used the microarray technology and observed the... -
- CITED
-
- Close
- SHARE
-
- Close
- Cholera toxin mediated regulation of the expression of Gq alpha and G11 alpha GTP binding proteins
-
Shah BH
- KMID: 1029937
- Exp Mol Med.
- 1999 Jun;31(2):89-94.
Previously it has been shown that persistent activation of the stimulatory adenylyl cyclase pathway with cholera toxin (CT) downregulates the Gs alpha polypeptide (80%) in a cAMP-independent manner in C6 glioma cells... -
- CITED
-
- Close
- SHARE
-
- Close
- Primary Intraosseous Malignant Fibrous Histiocytoma of the Skull: A Case Report
-
Joo M, Lee GJ, Koh YC, Kwon OK, Park YK
- KMID: 648920
- J Korean Med Sci.
- 2003 Aug;18(4):609-613.
- doi: 10.3346/jkms.2003.18.4.609
Malignant fibrous histiocytoma(MFH) is a rare primary neoplasm that constitutes less than 1% of the malignant tumors of bone, and involvement of the skull is very rare. We present a... -
- CITED
-
- Close
- SHARE
-
- Close
- Distribution of Adenoviral Vector in Brain after Intravenous Administration
-
Jin JY, Moon CI, Moon CI, Kang WS, Jeong DC
- KMID: 1099803
- J Korean Med Sci.
- 2003 Feb;18(1):108-111.
- doi: 10.3346/jkms.2003.18.1.108
The delivery of transgenes to the central nervous system (CNS) can be a valuable tool to treat CNS diseases. Various systems for the delivery to the CNS have been developed;... -
- CITED
-
- Close
- SHARE
-
- Close
- Enhanced immune response with foot and mouth disease virus VP1 and interleukin-1 fusion genes
-
Park JH, Kim SJ, Oem JK, Lee KN, Kim YJ, Kye SJ, Park JY, Joo YS
- KMID: 1089910
- J Vet Sci.
- 2006 Sep;7(3):257-262.
- doi: 10.4142/jvs.2006.7.3.257
The capsid of the foot and mouth disease (FMD) virus carries the epitopes that are critical for inducing the immune response. In an attempt to enhance the specific immune response,... -
- CITED
-
- Close
- SHARE
-
- Close
- Reconstitution of class I MHC molecules expressed in E. coli and complexed with single antigenic peptides
-
Kim J, Kim MY, Chwae YJ, Park JH
- KMID: 1081047
- J Korean Med Sci.
- 1997 Aug;12(4):280-285.
- doi: 10.3346/jkms.1997.12.4.280
The HLA-Cw3 heavy chain has been expressed at high level as insoluble protein aggregates in E. coli. The protein aggregates dissolved in strong denaturant solution were efficiently reconstituted by... -
- CITED
-
- Close
- SHARE
-
- Close
- NF-kappaB Binding Activity and Cyclooxygenase-2 Expression in Persistent betaCCI(4)-Treated Rat Liver Injury
-
Kim SH, Chu HJ, Kang DH, Song GA, Cho M, Yang US, Kim HJ, Chung HY
- KMID: 648675
- J Korean Med Sci.
- 2002 Apr;17(2):193-200.
- doi: 10.3346/jkms.2002.17.2.193
The involvement of NF-kappaB binding activity is known to be important in the mechanism of acute liver injury and in the induction of cyclooxygenase (COX-2). This study was performed to... -
- CITED
-
- Close
- SHARE
-
- Close
- Apoptotic Effects of Genistein, Biochanin-A and Apigenin on LNCaP and PC-3 Cells by p21 through Transcriptional Inhibition of Polo-like Kinase-1
-
Seo YJ, Kim BS, Chun SY, Park YK, Kang KS, Kwon TG
- KMID: 1123450
- J Korean Med Sci.
- 2011 Nov;26(11):1489-1494.
- doi: 10.3346/jkms.2011.26.11.1489
Natural isoflavones and flavones are important dietary factors for prostate cancer prevention. We investigated the molecular mechanism of these compounds (genistein, biochanin-A and apigenin) in PC-3 (hormone-independent/p53 mutant type) and... -
- CITED
-
- Close
- SHARE
-
- Close
- EGFR and KRAS Mutations in Patients With Adenocarcinoma of the Lung
-
Jang TW, Oak CH, Chang HK, Suo SJ, Jung MH
- KMID: 1785642
- Korean J Intern Med.
- 2009 Mar;24(1):48-54.
- doi: 10.3904/kjim.2009.24.1.48
BACKGROUND/AIMS: Mutations of the epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) are important in the pathogenesis of lung cancer, and recent reports have revealed... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of Recombinant Porcine Interleukin-2 and Application of Its Antibody to Immunoassays
-
Choi IS, Yoo HS
- KMID: 1095123
- J Vet Sci.
- 2002 Sep;3(3):207-212.
Interleukin-2 plays an important role in T lymphocyte proliferation and immune response regulations. In this study, porcine IL-2 cDNA was cloned from peripheral blood mononuclear cells, and recombinant porcine IL-2... -
- CITED
-
- Close
- SHARE
-
- Close
- Langerhans Cell Sarcoma Arising from Langerhans Cell Histiocytosis: A Case Report
-
Lee JS, Ko GH, Kim HC, Jang IS, Jeon KN, Lee JH
- KMID: 1778449
- J Korean Med Sci.
- 2006 Jun;21(3):577-580.
- doi: 10.3346/jkms.2006.21.3.577
Langerhans cell sarcoma (LCS) is a neoplastic proliferation of Langerhans cells that have overtly malignant cytologic features. It is a very rare disease and theoretically, it can present de novo... -
- CITED
-
- Close
- SHARE
-
- Close
