- Catastrophic Bronchial Spasm Due to a Severe Anaphylactic Reaction to Protamine
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Kim JB, Kim JH, Song KS
- KMID: 2362168
- Korean J Thorac Cardiovasc Surg.
- 2016 Dec;49(6):472-474.
- doi: 10.5090/kjtcs.2016.49.6.472
Fatal anaphylactic reactions to protamine sulfate during cardiac surgery are very rare. We report a case of catastrophic bronchial spasm due to an anaphylactic reaction to protamine. The patient was... -
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- Hypo-osmotic swelling test as a predictor for nuclear maturity of sperms assessed by aniline blue staining
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Jee BC, Moon SY
- KMID: 2269756
- Korean J Obstet Gynecol.
- 1999 Aug;42(8):1782-1788.
OBJECTIVE: Many cases of fertilization failure after ICSI is attributed to decondensation defect of sperm head, therefore, selection of sperm with well-condensed, fully-matured nucleus is critical for successful fertilization. During... -
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- Protamine Induced Anaphylactic Reaction after Cardiopulmonary Bypass: A case report
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Baek JH, Lee DH, Han SS, Lee JC, Jung TE, Lee JH
- KMID: 2062705
- Korean J Thorac Cardiovasc Surg.
- 2004 Jul;37(7):606-608.
Anaphylactic reaction to protamine sulfate, which is used widely to reverse the anticoagulative effect of heparin after cardiopulmonary bypass, is very rare. But the result of anaphylactic reaction can be... -
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- Effects of the Dose of Protamine Sulfate Calculated by the Dose Response Curve Method or the Fixed Dose Method on the Activated Coagulation Time
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Kim SK, Lee SK
- KMID: 2145922
- Korean J Anesthesiol.
- 1993 Jun;26(3):493-498.
- doi: 10.4097/kjae.1993.26.3.493
We studied 37 patients in order to evaluate the heparin-neutralizing efficacy of the protamine dose calculated by either the fixed dose method or the dose response curve method on... -
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- Acute Pulmonary Hypertension Associated with Protamine Neutralization of Systemic Heparinization during Open Heart Surgery
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Hwang KS, Cho MW
- KMID: 2237793
- Korean J Anesthesiol.
- 1996 Aug;31(2):269-274.
- doi: 10.4097/kjae.1996.31.2.269
Protamine sulfate, a strong polycationic polypeptide, combined with acidic heparin to form a neutral salt, eliminates the anticoagulating properties of heparin. Heparin reversal with protamine after cardiopulmonary bypass may complicate... -
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- Circulatory Changes and Blood Gas Analysis of Protamine Administration after Cardiopulmonary Bypass
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Kim TH, Koo BU, Park JW, Kim BK
- KMID: 2349611
- Korean J Anesthesiol.
- 1985 Dec;18(4):403-409.
Systemic hypotension is commonly observed in association with the administration of protamine after cardiopulmonary bypass. To elucidate the circulatory changes and arterial blood gas changes of protamine sulfate administration,... -
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- In Vitro Aprotinin Enhanced Anticoagulation Synergistically to Heparinized Blood on Thromboelastography
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Woo S, Sung KS, Hur CH, Kim MC, Cho KH
- KMID: 2091045
- Korean J Anesthesiol.
- 1997 Jan;32(1):74-78.
- doi: 10.4097/kjae.1997.32.1.74
BACKGROUND: Aprotinin is a potent, nonspecific broad serine protease inhibitor. It's inhibitory effects on intrinsic pathway of coagulation cascade can augment anticoagulation by heparin. This study designed to demonstrate augmented... -
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- Evaluation of sperm protamine deficiency and apoptosis in infertile men with idiopathic teratozoospermia
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Dehghanpour F, Tabibnejad N, Fesahat F, Yazdinejad F, Talebi AR
- KMID: 2405153
- Clin Exp Reprod Med.
- 2017 Jun;44(2):73-78.
- doi: 10.5653/cerm.2017.44.2.73
OBJECTIVE: Sperm morphology plays an important role in infertility, especially in cases of defects in the heads of spermatozoa. Tapered-head or elongated-head spermatozoa are examples of morphological abnormalities. The aim... -
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- Evaluation of Optimal Combination of Commercially Available Superparamagnetic Iron Oxide Nanoparticles and Transfection Agents for Labelling of Human Mesenchymal Stem Cells
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Kim SH, Oh SN, Park YH, Kang WK, Ahn KJ, Chung SK
- KMID: 2099835
- J Korean Soc Magn Reson Med.
- 2012 Apr;16(1):31-39.
- doi: 10.13104/jksmrm.2012.16.1.31
PURPOSE: To determine the optimal combination of commercially available superparamagnetic iron oxide (SPIO) nanoparticles with transfection agents (TA). MATERIALS AND METHODS: Protamine sulfate (Pro) and poly-L-lysin (PLL) were incubated with ferumoxide... -
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- Comparison of Superparamagnetic Iron Oxide Labeling Efficiency between Poly-L-Lysine and Protamine Sulfate for Human Mesenchymal Stem Cells: Quantitative Analysis Using Multi-Echo T2* Magnetic Resonance Imaging
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Suh JY, Lee JH, Lee CK, Shin JH, Choi CG, Kim JK
- KMID: 2097996
- J Korean Soc Radiol.
- 2013 Feb;68(2):175-185.
- doi: 10.3348/jksr.2013.68.2.175
PURPOSE: To quantify in vitro labeling efficiency of protamine sulfate (PS) and poly-L-lysine (PLL) for labeling of human mesenchymal stem cells (hMSCs) with superparamagnetic iron oxide (SPIO) using multi-echo T2*... -
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- Effects of Intravesical Instillation of Antimuscarinics on Bladder Overactivity Induced by Intravesical Instillation of Adenosine Triphosphate in Rats
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Lee SB, Lee JW, Kim YT
- KMID: 2311867
- Korean J Urol.
- 2009 Apr;50(4):396-400.
PURPOSE: Adenosine triphosphate (ATP) from the urothelium acts as a sensory neurotransmitter and is augmented in many diseases, such as overactive bladder. We investigated the effects of intravesical instillation of... -
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- Effect of Calcium Chloride on Protamine Sulfate-Induced Systemic Hypotension in Adult Open-Heart Patients
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Kim SJ, Jeong CY, Chung SS, Ha IH, Yoo KY
- KMID: 2236758
- Korean J Anesthesiol.
- 2002 Aug;43(2):157-164.
- doi: 10.4097/kjae.2002.43.2.157
BACKGROUND: Protamine sulfate (PS), used to neutralize the anticoagulant effect of heparin, is often associated with systemic hypotension. The present study was aimed to investigate the protective effects of... -
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- The Effect of Calcium Chloride on Hemodynamic Responses to Protamine Sulfate in the Dog
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Yoo KY, Jeong CW, Park JU, Jeong SW, Park CH, Ha IH
- KMID: 2239927
- Korean J Anesthesiol.
- 2003 Sep;45(3):377-384.
- doi: 10.4097/kjae.2003.45.3.377
BACKGROUND: Protamine sulfate (PS), used to neutralize the effect of heparin, is often associated with systemic hypotension. The present study was aimed to investigate the protective effects of CaCl2 on... -
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- The Effect of Inhaled Nitric Oxide on Protamine Sulfate-Induced Hypotension in Dogs
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Yoo KY, Jeong CW, Kwak SH, Yoon MH
- KMID: 1860695
- Korean J Anesthesiol.
- 2003 Jan;44(1):103-110.
- doi: 10.4097/kjae.2003.44.1.103
BACKGROUND: Protamine sulfate has been found to produce systemic hypotension secondary to acute pulmonary vasoconstriction and subsequent right heart failure in pigs and sheep. Nitric oxide (NO) is a potent... -
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- Mechanism of the Hypotension Produced Protamine Sulfate in Dogs
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Yoo KY, Rim SJ, Shim SJ, Chung SS, Im WM
- KMID: 2032339
- Korean J Anesthesiol.
- 1998 Jan;34(1):27-38.
- doi: 10.4097/kjae.1998.34.1.27
INTRODUCTION: Protamine reversal of heparin anticoagulation often produces profound hypotension. However, the precise mechanisms of its hypotensive effect have not been fully elucidated. Using a canine model, we explored the... -
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- Effects of Twice-Daily Injections of Premixed Insulin Analog on Glycemic Control in Type 2 Diabetic Patients
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Shimizu H, Monden T, Matsumura , Domeki N, Kasai K
- KMID: 1779629
- Yonsei Med J.
- 2010 Nov;51(6):845-849.
- doi: 10.3349/ymj.2010.51.6.845
PURPOSE: Premixed insulin is effective to improve glycemic control; however, clinicians may be less likely to know which premixed insulin is appropriate for which patients. This study aimed to evaluate... -
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