Korean J Thorac Cardiovasc Surg.  2016 Dec;49(6):472-474. 10.5090/kjtcs.2016.49.6.472.

Catastrophic Bronchial Spasm Due to a Severe Anaphylactic Reaction to Protamine

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Dongsan Medical Center, Keimyung University School of Medicine, Korea. juggang@dsmc.or.kr

Abstract

Fatal anaphylactic reactions to protamine sulfate during cardiac surgery are very rare. We report a case of catastrophic bronchial spasm due to an anaphylactic reaction to protamine. The patient was managed successfully using a bronchodilator, steroid treatment, and extracorporeal membrane oxygenation.

Keyword

Protamines; Bronchial spasm; Extracorporeal menbrane oxygenation

MeSH Terms

Anaphylaxis*
Bronchial Spasm*
Extracorporeal Membrane Oxygenation
Humans
Protamines
Thoracic Surgery
Protamines
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