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Analysis of Changes in Retinal Photoreceptors Using Optical Coherence Tomography in a Feline Model of Iodoacetic Acid-induced Retinal Degeneration

Noh GM, Lim JW, Lee MS, Lee SU, Lee SJ

PURPOSE: We investigated structural changes in the retina by using optical coherence tomography (OCT) in a feline model of retinal degeneration using iodoacetic acid (IAA). METHODS: We examined 22 eyes of...
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Generation of Retinal Progenitor Cells from Human Induced Pluripotent Stem Cell-Derived Spherical Neural Mass

Yun C, Oh J, Lee B, Lee JM, Ariunaa T, Huh K

Spherical neural mass (SNM) is a mass of neural precursors that have been used to generate neuronal cells with advantages of long-term passaging capability with high yield, easy storage, and...
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A Case of Transient Color Anomaly and Persistent Visual Field Defect after Sildenafil Citrate Overdose

Kim P, Kim SY

PURPOSE: Sildenafil citrate, is an oral tablet demonstrating efficacy for maintaining an erection in males with erectile dysfunction by inhibiting phosphodiesterase type 5 (PDE5). In the present study, we report...
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Na, K-ATPase beta2 isoform (atp1b2) expressed in the retina of Xenopus

Rahman MM, Park BY

The ubiquitous Na, K-ATPase is a membrane-bound ion pump located in the plasma membrane in all animal cells and plays an essential role in a variety of cellular functions. Studies...
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A Case of Oxaliplatin-Related Ocular Toxicity

Park HS, Kim YJ, Song SJ, Bae JH

  • KMID: 2338604
  • J Korean Ophthalmol Soc.
  • 2014 Jan;55(1):143-148.
PURPOSE: To report a case of oxaliplatin (Eloxatin(R))-related ocular toxicity in a patient with advanced stomach cancer. CASE SUMMARY: A 43-year-old female with advanced stomach cancer experienced visual symptoms during the...
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Morphologic Characteristics of the Outer Retina in Cone Dystrophy on Spectral-domain Optical Coherence Tomography

Cho SC, Woo SJ, Park KH, Hwang JM

PURPOSE: To investigate the morphologic changes in the outer retina of patients with cone dystrophy, using spectral-domain optical coherence tomography (SD-OCT). METHODS: The medical records of 15 cone dystrophy patients examined...
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Photoreceptor Disruption Related to Persistent Submacular Fluid after Successful Scleral Buckle Surgery

Woo SJ, Lee KM, Chung H, Park KH

PURPOSE: To investigate serial changes in photoreceptor status and associated visual outcome in patients with persistent submacular fluid after successful scleral buckle surgery for macula-off rhegmatogenous retinal detachment. METHODS: This was...
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Immunohistochemical localization of cyclic AMP-responsive element binding protein (CREB)-binding protein in the pig retina during postnatal development

Oh H, Kim H, Ahn M, Jeong C, Jeong J, Moon C, Shin T

This study evaluated the cellular localization of cyclic AMP-responsive element binding protein-binding protein (CBP) expression in pig retinas during postnatal development. Immunohistochemistry and Western blot analysis were performed on retinal...
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Characterization of Peripapillary Atrophy Using Spectral Domain Optical Coherence Tomography

Na JH, Moon BG, Sung KR, Lee Y, Kook MS

PURPOSE: To characterize the features of peripapillary atrophy (PPA), as imaged by spectral-domain optical coherence tomography (SD-OCT). METHODS: SD-OCT imaging of the optic disc was performed on healthy eyes, eyes...
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Stem Cell Based Strategies for the Treatment of Degenerative Retinal Diseases

Park JH, Ku SY, Cho MS, Lee H, Choi YM, Moon SY, Yu HG

  • KMID: 2070997
  • Korean J Reprod Med.
  • 2010 Sep;37(3):199-206.
Stem-cell therapy has the potential to improve vision in patients with untreatable retinal disease. Various types of cell source including fetal, embryonic and adult stem cells, intrinsic and extrinsic factors...
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Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes

Chung SE, Lim DH, Kang SW, Yoon YH, Chae JB, Roh IH

PURPOSE: To identify the correlation between preoperative optical coherence tomography (OCT) features and postoperative visual outcomes in eyes with idiopathic macular holes (MHs). METHODS: Data from 55 eyes with idiopathic...
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Edema of the Photoreceptor Layer in Vogt-Koyanagi-Harada Disease Observed Using High-Resolution Optical Coherence Tomography

Lee JE, Park SW, Lee JK, Choi HY, Oum BS, Kim HW

PURPOSE: To evaluate the characteristics of fluid accumulation in the uveitic stage of Vogt-Koyanagi-Harada (VKH) disease using high resolution optical coherence tomography (OCT3). METHODS: Twenty-eight eyes in 14 patients with...
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Ophthalmologic Findings of Boucher-Neuhauser Syndrome

Yu SI, Kim JL, Lee SG, Kim HW, Kim SJ

To report a case of Boucher-Neuhauser syndrome, which is an autosomal recessive disorder characterized by the triad of spinocerebellar ataxia, chorioretinal dystrophy, and hypogonadotropic hypogonadism. An 18-year-old man was seen...
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Reorganization of Photoreceptor Layer on Optical Coherence Tomography Concurrent with Visual Improvement after Macular Hole Surgery

Lee JE, Lee SU, Jea SY, Choi HY, Oum BS

To report three cases in which reorganization of the photoreceptor layer on optical coherence tomography (OCT) was concurrent with long-term visual recovery after macular hole surgery. Serial OCT scans of...
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Structural Alterations of Retinal Detachment After Intravitreal Triamcinolone Injection in Rabbit Eyes

Kim M, Lee YC, Park YH

PURPOSE: To investigate the effect of localized retinal detachment on both the detached and attached regions, and to determine the effect of triamcinolone on Muller cell gliosis. METHODS: Pars plana vitrectomy...
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Early Reversible Changes on ERG in Pharmaceutically Induced Retinal Degeneration in Rats

Roh KH, Park TK, Ohn YH

  • KMID: 2208439
  • J Korean Ophthalmol Soc.
  • 2006 Jul;47(7):1117-1125.
PURPOSE: To evaluate the early ERG (electroretinogram) changes in N-methyl-N-nitrosourea (MNU)-induced retinal degeneration in rats. METHODS: Thirty-six 6-week-old male rats were injected intraperitoneally with 60mg/kg MNU and divided into 6 groups....
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The Changes on Electroretinogram Following Sildenafil Ingestion

Lee G, Kim S, Park Y

  • KMID: 2206747
  • J Korean Ophthalmol Soc.
  • 2003 Dec;44(12):2804-2810.
PURPOSE: Sildenafil citrate (Viagra(R)) acts as a relatively specific inhibitor of the type 5 phosphodiesterase isoenzyme (PDE5) in the corpus cavernosum. But, it also has a mild inhibitory effect on...
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Enzyme Histochemical Identification of a Subtype of Cone Photoreceptor in the Mammalian Retina

Choi GH, Cho NC

  • KMID: 2125264
  • J Korean Ophthalmol Soc.
  • 2002 Nov;43(11):2323-2328.
PURPOSE: To identify a subtype of cone photoreceptor in the mammalian retina using enzyme histochemical method. METHODS: In human, rabbits and cats, identification of cone photoreceptor was tried with carbonic anhydrase...
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Expression of Vascular Endothelial Growth Factor after Laser Induced Retinal Vein Occlusion in the Rat Eye

Kim YJ, Oh JH, Han JA, Cho HK

  • KMID: 2109301
  • J Korean Ophthalmol Soc.
  • 2002 Mar;43(3):589-598.
PURPOSE: To examine the effects of retinal vein occlusion (RVO) on VEGF expression and the ultrastructural change of the various ocular tissues in the rat. METHODS: Sprauge Dawley rats were grouped...
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Immunohistochemical localization of heme oxygenase isozymes in the aged rat retina

Lee HY

  • KMID: 1558433
  • Korean J Anat.
  • 2001 Apr;34(2):169-179.
Heme oxygenase (HO)-1 and -2 isozymes are important markers for the oxidative stress. We localized HO-1 and HO-2 immunoreactivities and assessed the effect of aging on distribution of HO in...
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