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Deep Learning-Assisted Diagnosis of Pediatric Skull Fractures on Plain Radiographs

Choi JW, Choi JW, Cho YJ, Ha JY, Lee YY, Koh SY, Seo JY, Choi YH, Cheon JE, Phi JH, Kim I, Yang J, Kim WS

Objective: To develop and evaluate a deep learning-based artificial intelligence (AI) model for detecting skull fractures on plain radiographs in children. Materials and Methods: This retrospective multi-center study consisted of a...
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Clinicopathological Features of Primary Solitary Spinal Cord Tumors in Pediatric Patients : A 32-Year Single Institution Experience

Choi HY, Kim KH, Cho BK, Wang KC, Phi JH, Lee JY, Park SH, Kim SK

Objective : Few studies exist on primary spinal cord tumors (PSCTs) in pediatric patients. The purpose of this study was to perform descriptive analysis and detailed survival analysis for PSCTs. Methods...
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Sacrococcygeal Teratoma : A Tumor at the Center of Embryogenesis

Phi JH

Sacrococcygeal teratoma (SCT) is an extragonadal germ cell tumor (GCT) that develops in the fetal and neonatal periods. SCT is a type I GCT in which only teratoma and yolk...
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Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System in Children under the Age of 3 Years

Park M, Han JW, Hahn SM, Lee JA, Kim JY, Shin SH, Kim DS, Yoon HI, Hong KT, Choi JY, Kang HJ, Shin HY, Phi JH, Kim SK, Lee JW, Yoo KH, Sung KW, Koo HH, Lim DH, Shin HJ, Kim H, Koh KN, Im HJ, Ahn SD, Ra YS, Baek HJ, Kook H, Jung TY, Choi HS, Kim CY, Park HJ, Lyu CJ

Purpose Atypical teratoid/rhabdoid tumor (ATRT) is a highly aggressive malignancy with peak incidence in children aged less than 3 years. Standard treatment for central nervous system ATRT in children under...
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Characteristics and Treatment Outcome of Intracranial Aneurysms in Children and Adolescents

Nam SM, Jang D, Wang KC, Kim SK, Phi JH, Lee JY, Cho WS, Kim JE, Kang HS

OBJECTIVE: Intracranial aneurysms are not common in young age patients. We sought to find the characteristics of the intracranial aneurysms in patients under 20 years of age. METHODS: We reviewed 23...
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Epilepsy Surgery in 2019: A Time to Change

Phi JH, Cho BK

Epilepsy has been known to humankind since antiquity. The surgical treatment of epilepsy began in the early days of neurosurgery and has developed greatly. Many surgical procedures have stood the...
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The Present and Future of Vagus Nerve Stimulation

Yang J, Phi JH

Epilepsy is one of the major chronic neurological diseases affecting many patients. Resection surgery is the most effective therapy for medically intractable epilepsy, but it is not feasible in all...
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Clinical Pearls and Advances in Molecular Researches of Epilepsy-Associated Tumors

Phi JH, Kim SK

Brain tumors are the second most common type of structural brain lesion that causes chronic epilepsy. Patients with low-grade brain tumors often experience chronic drug-resistant epilepsy starting in childhood, which...
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Antiepileptic Drug Withdrawal after Surgery in Children with Focal Cortical Dysplasia: Seizure Recurrence and Its Predictors

Choi SA, Kim SY, Kim WJ, Shim YK, Kim H, Hwang H, Choi JE, Lim BC, Chae JH, Chong S, Lee JY, Phi JH, Kim SK, Wang KC, Kim KJ

BACKGROUND AND PURPOSE: This study investigated the seizure recurrence rate and potential predictors of seizure recurrence following antiepileptic drug (AED) withdrawal after resective epilepsy surgery in children with focal cortical...
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Surgical Outcomes of Thalamic Tumors in Children: The Importance of Diffusion Tensor Imaging, Neuro-Navigation and Intraoperative Neurophysiological Monitoring

Kim JH, Phi JH, Lee JY, Kim KH, Park SH, Choi YH, Cho BK, Kim SK

BACKGROUND: Recently, modern technology such as diffusion tensor imaging (DTI), neuro-navigation and intraoperative neurophysiological monitoring (IOM) have been actively adopted for the treatment of thalamic tumors. We evaluated surgical outcomes...
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Aberrant Promoter Hypomethylation of Sortilin 1: A Moyamoya Disease Biomarker

Sung HY, Lee JY, Park AK, Moon YJ, Jo I, Park EM, Wang KC, Phi JH, Ahn JH, Kim SK

BACKGROUND AND PURPOSE: The pathogenesis of moyamoya disease (MMD) remains poorly understood, and no reliable molecular biomarkers for MMD have been identified to date. The present study aimed to identify...
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Cavernous Malformations at Optic Apparatus: Three Cases

Kim HS, Phi JH, Kim JE, Lee JY, Kim SK, Wang KC, Cho WS

Cavernous malformations (CMs) are angiographically occult vascular lesions, and their clinical presentations vary widely according to location of the lesion. Here, we reviewed three cases of CM located at the...
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Postoperative Transient Neurologic Dysfunction: A Proposal for Pathophysiology

Phi JH, Lee SJ, Kang HS, Kim JE, Kim SK, Cho WS, Lee SY

BACKGROUND AND PURPOSE: Sudden neurological deterioration which cannot be explained by structural change, ischemia or seizure is often observed among neurosurgical patients. We aimed to provide new insight into the...
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Thyroid dysfunction in patients with childhood-onset medulloblastoma or primitive neuroectodermal tumor

Jin SY, Choi JY, Park KD, Kang HJ, Shin HY, Phi JH, Kim SK, Wang KC, Kim IH, Lee YA, Shin CH, Yang SW

PURPOSE: We investigated the clinical characteristics of patients who developed thyroid dysfunction and evaluated the risk factors for hypothyroidism following radiotherapy and chemotherapy in pediatric patients with medulloblastoma or primitive...
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Intraoperative Neurophysiological Monitoring : A Review of Techniques Used for Brain Tumor Surgery in Children

Kim K, Cho C, Bang MS, Shin HI, Phi JH, Kim SK

Intraoperative monitoring (IOM) utilizes electrophysiological techniques as a surrogate test and evaluation of nervous function while a patient is under general anesthesia. They are increasingly used for procedures, both surgical...
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Intracranial Germ Cell Tumor in the Molecular Era

Phi JH, Wang KC, Kim SK

Intracranial germ cell tumors (iGCTs) are a heterogeneous group of tumors with peculiar characteristics clearly distinguished from other brain tumors of neuroepithelial origin. Diverse histology, similarity to gonadal GCT, predilection...
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Coexistence of Radiation-Induced Meningioma and Moyamoya Syndrome 10 Years after Irradiation against Medulloblastoma: a Case Report

Han JY, Choi JW, Wang KC, Phi JH, Lee JY, Chae JH, Park SH, Cheon JE, Kim SK

Radiotherapy is one of the standard treatments for medulloblastoma. However, therapeutic central nervous system irradiation in children may carry delayed side effects, such as radiation-induced tumor and vasculopathy. Here, we...
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Endoscopic Endonasal Approach for Suprasellar Lesions in Children: Complications and Prevention

Kim YH, Wang KC, Phi JH, Kim SK

The endoscopic endonasal approach (EEA) has been popularized in adults and has been applied to an expanding range of surgical modules and indications in this population. However, its clinical application...
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Prevention of Complications in Endoscopic Third Ventriculostomy

Jung TY, Chong S, Kim IY, Lee JY, Phi JH, Kim SK, Kim JH, Wang KC

A variety of complications in endoscopic third ventriculostomy have been reported, including neurovascular injury, hemodynamic alterations, endocrinologic abnormalities, electrolyte imbalances, cerebrospinal fluid leakage, fever and infection. Even though most complications...
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Minimally Invasive Suturectomy and Postoperative Helmet Therapy : Advantages and Limitations

Chong S, Wang KC, Phi JH, Lee JY, Kim SK

Various operative techniques are available for the treatment of craniosynostosis. The patient's age at presentation is one of the most important factors in the determination of the surgical modality. Minimally...
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