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Effects of Pertussis Toxin on the Differentiation of B Lymphocytes in Lymph Node

Kim JG, Ko SH

  • KMID: 1573003
  • Korean J Immunol.
  • 2000 Jun;22(2):71-80.
No abstract available.
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Investigation on the Immunity to Pertussis in the Korea

Kim HH, Shin KH, Kim SN, Lee MS, Yoo SH, Kim JY, Kang JH

  • KMID: 2099318
  • J Korean Soc Microbiol.
  • 1999 Dec;34(6):583-589.
Acellular pertussis vaccine has been used widely in Korea since 1984. However, because many of the former generations were not inoculated with pertussis vaccine, they may infect infants with pertussis....
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Role of pertussis toxin sensitive G-proteins on signal transduction of thyrotropin and insulin-like growth factor-I for the growth of thyrocytes

Cho BY, Lee DS, Yi KH, Shong MH, Lee HK, Koh CS, Min HK

  • KMID: 1697933
  • Korean J Intern Med.
  • 1991 Jul;41(1):94-102.
No abstract available.
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Pertussis Seroprevalence in Korean Adolescents and Adults Using Anti-Pertussis Toxin Immunoglobulin G

Lee SY, Han SB, Bae EY, Kim JH, Kang JH, Park YJ, Ma SH

This study was conducted to evaluate age-specific seroprevalence of pertussis in Korea and to formulate a strategy to prevent and reduce the incidence of pertussis. Residual serum samples of healthy...
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Enzyme-linked immunosorbent assay for detecting anti-pertussis toxin antibody in mouse

Choi GS, Huh DH, Han SB, Ahn DH, Kang KR, Kim JA, Choi BM, Kim HR, Kang JH

PURPOSE: Although the DTaP and Tdap vaccines used to prevent pertussis have been used for a long time, there is no standard method for measuring pertussis antigens. Therefore, this preliminary...
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Effects of pertussis and cholera toxin on oxidized low density lipoprotein induced apoptosis in cultured bovine aortic endothelial cells

Chang SA, Choi YH, Moon SD, Ahn YB, Son HS, Yoon KH, Kang MI, Cha BY, Lee KW, Son HY, Kang SK

  • KMID: 1985577
  • Korean J Med.
  • 1999 May;56(5):598-605.
OBJECTIVES: Oxidized LDL is thought to play a key role in atherogenesis. Among their wide variety of biological properties, oxidized LDL injures the endothelium as an early event of atherogenesis. However, the...
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Preliminary study on the immunogenicity of a newly developed GCC Tdap vaccine and its protection efficacy against Bordetella pertussis in a murine intranasal challenge model

Han SB, Kang KR, Huh DH, Lee HC, Lee SY, Kim JH, Hur JK, Kang JH

PURPOSE: Active reduced dose tetanus-diphtheria-acellular pertussis (Tdap) vaccination for adolescents and adults is necessary because waning immunity after primary diphtheria-tetanus-pertussis vaccination is related to the recent emergence of pertussis. This...
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G-protein Effects on [ 3H]RX821002 Binding to Alpha-2 Adrenoceptor in Rat Brain

Chung IW, Shin JY, Shin CJ

  • KMID: 1985334
  • Korean J Psychopharmacol.
  • 2001 Dec;12(4):301-309.
OBJECTIVE: This study is to explore the effects on specific bindings between [ 3H]RX821002, alpha-2 adrenergic receptor antagonist and alpha-2 adrenergic receptor in rat brain by G-protein modulation. METHODS: The radioligand...
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The immunogenicity and safety of three-component DTaP vaccine in Korean infants

Kang JH, Kim JH, Lee JH, Lee SY, Hong YJ, Kim CH

PURPOSE: We conducted the study to evaluate the immunogenicity and safety of three component DTaP vaccine (Infanrix(R)) in a group of Korean healthy infants on a three-dose primary vaccination. And...
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Recent Trends of Antigenic Variation in Bordetella pertussis Isolates in Korea

Kim SH, Lee J, Sung HY, Yu JY, Kim SH, Park MS, Jung SO

Pertussis is a representative vaccine-preventable disease. However, there have been recent outbreaks in countries where even higher vaccination against the disease. One reason is the emergence of antigenic variants, which...
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Development and implementation of standardized method for detecting immunogenicity of acellular pertussis vaccines in Korea

Park C, Huh DH, Han SB, Choi GS, Kang KR, Kim JA, Kang JH

PURPOSE: There is no standard method for confirming the immunogenicity of acellular pertussis vaccines. We tried to develop a local standard method for evaluating the immunogenicity of the three-component of...
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Immunoassay of Pertussis According to Ages

Lee SY, Choi UY, Kim JS, Ahn JH, Choi JH, Ma SH, Park JS, Kim HM, Kang JH

  • KMID: 1439526
  • Korean J Pediatr Infect Dis.
  • 2012 Aug;19(2):55-60.
PURPOSE: We conducted the immunoassay of pertussis according to ages, in order to evaluate protective immunity against pertussis in Korean populations. METHODS: Healthy subjects were enrolled at four university hospitals in...
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Intracellular signal transduction of interleukin-6 production bylipopolysaccharide-stimulated fibroblasts

Joo JH, Ki SY, Moon SH, Jung SH, Kim HT, Uh ST, Kim YH, Park CS

  • KMID: 2143163
  • Korean J Med.
  • 1998 Mar;54(3):415-422.
OBJECTIVES: Stimulation of cell results in a variety of early biochemical events, known as signal transduction pathway and ultimately leads to final outcome like cell proliferation or cytokine production. The...
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alpha-Adrenergic and cholinergic receptor agonists modulate voltage-gated Ca2+ channels

Nah SY, Kim JH, Kim CH

  • KMID: 1554758
  • Korean J Physiol Pharmacol.
  • 1997 Oct;1(5):485-493.
We investigated the effect of alpha-adrenergic and cholinergic receptor agonists on Ca2+ current in adult rat trigeminal ganglion neurons using whole-cell patch clamp methods. The application of acetylcholine, carbachol, and oxotremorine (50 muM...
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Effect of pertussis toxin pretreated centrally on blood glucose level induced by stress

Suh HW, Sim YB, Park SH, Sharma N, Im HJ, Hong JS

In the present study, we examined the effect of pertussis toxin (PTX) administered centrally in a variety of stress-induced blood glucose level. Mice were exposed to stress after the pretreatment...
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Allergic Rhinitis Model Using Brown-Norway Rats

Kim HY, Dhong HJ, Chung SK

  • KMID: 2276512
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Nov;48(11):1341-1346.
BACKGROUND AND OBJECTIVES: The necessity of a well established allergic rhinitis model is needed for the research of pathophysiology and therapeutic trial of allergic rhinitis. We investigated the potential of...
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Phytosphingosine-1-phosphate stimulates chemotactic migration of L2071 mouse fibroblasts via pertussis toxin-sensitive G-proteins

Kim MK, Park KS, Lee H, Kim YD, Yun J, Bae YS

  • KMID: 1094659
  • Exp Mol Med.
  • 2007 Apr;39(2):185-194.
Phytosphingosine-1-phosphate (PhS1P) was found to stimulate an intracellular calcium increase via phospholipase C but not pertussis toxin (PTX)- sensitive G-proteins in L2071 mouse fibroblasts. PhS1P also activated ERK and p38...
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Effect of Oxidezed LDL in Insulin Binding, Internalization and Recycling of Insulin Receptor in Cultured Bovine Aortic Endothelial Cells

Moon SD, Cha BY, Kim HS, Jang SA, An YB, Song KH, Han JH, You SJ, Yoon KH, Kang MI, Lee KW, Son HY, Kang SK

  • KMID: 2063337
  • J Korean Diabetes Assoc.
  • 1999 Jun;23(3):243-255.
BACKGROUND: Endothelial dysfunction is perhaps one of the earliest manifestations of atherosclerosis. This abnormality is in part due to altered membrane signal transduction in endothelial cells. Oxidized LDL that is...
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Role of Pertussis Toxin-sensitive G Protein-coupled Receptor Signaling in the Proliferation of Bone Marrow Mesenchymal Stem Cells

Kim SW, Hwang JH, Jin SA, Yun GW, Yang YJ, Park NW, Lee HJ, Yun HJ, Jo DY, Kim S

BACKGROUND: Bone marrow (BM) mesenchymal stem cells (MSCs) can be expanded over 20~30 cell doublings in vitro even in the absence of any growth factors. However, the mechanisms that govern...
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P2 Receptor-mediated Inhibition of Vasopressin-stimulated Fluid Transport and cAMP Responses in AQP2-transfected MDCK Cells

Kim YH, Choi YJ, Bae HR, Woo JS

We cultured canine kidney (MDCK) cells stably expressing aquaporin-2 (AQP2) on collagen-coated permeable membrane filters and examined the effect of extracellular ATP on arginine vasopressin (AVP)-stimulated fluid transport and cAMP...
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