- Tactics of Mycobacterium avium subsp. paratuberculosis for intracellular survival in mononuclear phagocytes
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Woo SR, Czuprynski CJ
- KMID: 1102947
- J Vet Sci.
- 2008 Mar;9(1):1-8.
- doi: 10.4142/jvs.2008.9.1.1
Johne's disease is a condition that refers to chronic granulomatous enteritis in ruminants. It is believed that survival and replication of Mycobacterium (M.) paratuberculosis in mononuclear phagocytes plays an important... -
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- Development of vaccines to Mycobacterium avium subsp. paratuberculosis infection
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Park HT, Yoo HS
- KMID: 2421557
- Clin Exp Vaccine Res.
- 2016 Jul;5(2):108-116.
- doi: 10.7774/cevr.2016.5.2.108
Johne's disease or paratuberculosis is a chronic debilitating disease in ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). The disease causes significant economic losses in livestock industries worldwide. There are... -
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- Immunohistochemical localization of galectin-3 in the granulomatous lesions of paratuberculosis-infected bovine intestine
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Lee J, Moon C, Kim J, Jung C, Lee KH, Joo HG, Ahn M, Shin T
- KMID: 1726915
- J Vet Sci.
- 2009 Sep;10(3):177-180.
- doi: 10.4142/jvs.2009.10.3.177
The presence of galectin-3 was immunohistochemically quantified in bovine intestines infected with paratuberculosis (Johne's disease) to determine whether galectin-3 was involved in the formation of granulation tissue associated with the... -
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- Rapid visual detection of Mycobacterium avium subsp. paratuberculosis by recombinase polymerase amplification combined with a lateral flow dipstick
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Zhao G, Wang H, Hou P, He C, He H
- KMID: 2407623
- J Vet Sci.
- 2018 Mar;19(2):242-250.
- doi: 10.4142/jvs.2018.19.2.242
Paratuberculosis (Johne's disease) is a chronic debilitating disease of domestic and wild ruminants. However, widespread point-of-care testing is infrequent due to the lack of a robust method. The isothermal recombinase... -
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- Effective DNA extraction method to improve detection of Mycobacterium avium subsp. paratuberculosis in bovine feces
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Park HT, Shin MK, Sung KY, Park HE, Cho YI, Yoo HS
- KMID: 1700792
- Korean J Vet Res.
- 2014 Mar;54(1):55-57.
Paratuberculosis caused by Mycobacterium avium subsp. paratuberculosis (MAP) has extended latent periods of infection. Due to this property, difficulties in the detection of fecal shedder have been raised. A newly... -
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- Estimation of Paratuberculosis Prevalence in Dairy Cattle in a Province of Korea using an Enzyme-linked Immunosorbent Assay: Application of Bayesian Approach
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Pak SI, Kim D, Salman M
- KMID: 1099821
- J Vet Sci.
- 2003 Apr;4(1):51-56.
To draw inferences about the sensitivity and specificity of the newly developed ELISA test for bovine paratuberculosis (PTB) diagnosis and posterior distribution on the prevalence of PTB in a province... -
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- Analysis of the seroprevalence of bovine paratuberculosis and the application of modified absorbed ELISA to field sample testing in Korea
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Park KT, Ahn J, Davis WC, Koo HC, Kwon NH, Jung WK, Kim JM, Hong SK, Park YH
- KMID: 1089482
- J Vet Sci.
- 2006 Dec;7(4):349-354.
- doi: 10.4142/jvs.2006.7.4.349
Paratuberculosis (PTB) is a major disease problem worldwide, and causes major economic losses in the dairy industry. Although PTB has been reported in Korea, no studies have been conducted to... -
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- A novel low-cost method for Mycobacterium avium subsp. paratuberculosis DNA extraction from an automated broth culture system for real-time PCR analysis
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Salgado M, Verdugo C, Heuer C, Castillo P, Zamorano P
- KMID: 1784644
- J Vet Sci.
- 2014 Jun;15(2):233-239.
- doi: 10.4142/jvs.2014.15.2.233
PCR is a highly accurate technique for confirming the presence of Mycobacterium avium subsp. paratuberculosis (Map) in broth culture. In this study, a simple, efficient, and low-cost method of harvesting... -
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- Genetic diversity of bovine Mycobacterium avium subsp. paratuberculosis discriminated by IS1311 PCR-REA, MIRU-VNTR, and MLSSR genotyping
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Park HT, Park HE, Park WB, Kim S, Hur TY, Jung YH, Yoo HS
- KMID: 2420931
- J Vet Sci.
- 2018 Sep;19(5):627-634.
- doi: 10.4142/jvs.2018.19.5.627
The aim of this study was to describe the genetic diversity of Mycobacterium avium subsp. paratuberculosis (MAP) obtained from individual cows in Korea. Twelve MAP-positive fecal DNA samples and 19... -
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- Potential biomarkers as an indicator of vertical transmission of Johne's disease in a Korean native cattle farm
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Park HT, Park HE, Cho YI, Kim EH, Jung M, Shin SW, Lee SH, Kim DY, Yoo HS
- KMID: 2412559
- J Vet Sci.
- 2017 Aug;18(S1):343-349.
- doi: 10.4142/jvs.2017.18.S1.343
Paratuberculosis (PTB) is caused by Mycobacterium avium subsp. paratuberculosis (MAP) and is one of the most widespread and economically important diseases in cattle. After birth, calves are raised with natural... -
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- Comparative antibody response of five recombinant antigens in related to bacterial shedding levels and development of serological diagnosis based on 35 kDa antigen for Mycobacterium avium subsp. paratuberculosis
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Shin SJ, Yoo HS, McDonough , Chang YF
- KMID: 1120066
- J Vet Sci.
- 2004 Jun;5(2):111-117.
Eighty-five complex (85A, 85B and 85C), 35-kDa and superoxide dismutase (SOD) were cloned, expressed and purified as antigens in an enzyme-linked immunosorbent assay (ELISA) to compare the serological reactivity of... -
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- Discovery of antigens for early detection of Mycobacterium avium subsp. paratuberculosis and analysis of characteristics using bioinformatics tools
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Park HT, Park HE, Shin MK, Cho YI, Yoo HS
- KMID: 1807796
- Korean J Vet Res.
- 2015 Jun;55(2):89-95.
- doi: 10.14405/kjvr.2015.55.2.89
Johne's disease, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is one of the most widespread and economically important diseases in cattle. Current diagnostic methods are based on the detection of... -
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- Gene Expression Profiles of Th1-type Chemokines in Whole Blood of Mycobacterium avium subsp. paratuberculosis-Infected Cattle
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Shin MK, Park HE, Park HT, Jung M, Kang HL, Baik SC, Lee WK, Jung YH, Yoo HS
- KMID: 2452065
- J Bacteriol Virol.
- 2018 Dec;48(4):130-136.
- doi: 10.4167/jbv.2018.48.4.130
Johne's disease (JD) is a chronic, debilitating disease of ruminants including cows, and is caused by Mycobacterium avium subsp. paratuberculosis (MAP). MAP is not only important in animal husbandry, but... -
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- A biosensor assay for the detection of Mycobacterium avium subsp. paratuberculosis in fecal samples
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Kumanan V, Nugen SR, Baeumner A, Chang YF
- KMID: 1089344
- J Vet Sci.
- 2009 Mar;10(1):35-42.
- doi: 10.4142/jvs.2009.10.1.35
A simple, membrane-strip-based lateral-flow (LF) biosensor assay and a high-throughput microtiter plate assay have been combined with a reverse transcriptase polymerase chain reaction (RT-PCR) for the detection of a small... -
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- Case report of Johne's disease in Korean black goat (Capra hircus aegagrus)
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Rhyoo MY, Jung JY, Lee KH, Her JW, Bae YC, Lee HK, Baek KH, Lee BR, Jean YH, Kim JM, Lee MH, Yoon SS
- KMID: 1790578
- Korean J Vet Res.
- 2013 Dec;53(4):273-276.
Two Korean black goat (approx. 2 and 3 years old) showing diarrhea and chronic weight loss were submitted to Animal and Plant Quarantine Agency. At necropsy, there were thickening of... -
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- The Role of Bacteria in the Pathogenesis of Inflammatory Bowel Disease
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Friswell M, Campbell B, Rhodes J
- KMID: 1974129
- Gut Liver.
- 2010 Sep;4(3):295-306.
Crohn's disease (CD) and ulcerative colitis (UC) have features that suggest bacterial involvement, and all genetic models of inflammatory bowel disease (IBD) require the presence of commensal bacteria. CD is... -
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- The Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein, a toll-like receptor 4 agonist, enhances dendritic cell-based cancer vaccine potency
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Noh KT, Shin SJ, Son KH, Jung ID, Kang HK, Lee SJ, Lee EK, Shin YK, You JC, Park YM
- KMID: 1383795
- Exp Mol Med.
- 2012 May;44(5):340-349.
In this study, we showed the direct interaction between Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein (FAP) and toll-like receptor4 (TLR4) via co-localization and binding by using confocal microscopy and... -
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