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Applications of kidney organoids derived from human pluripotent stem cells

Kim YK, Nam SA, Yang CW

The establishment of protocols to differentiate kidney organoids from human pluripotent stem cells provides potential applications of kidney organoids in regenerative medicine. Modeling of renal diseases, drug screening, nephrotoxicity testing...
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Implication of Porphyromonas gingivalis in colitis and homeostasis of intestinal epithelium

Seo Y, Oh SJ, Ahn JS, Shin YY, Yang JW, Kim HS

Emerging evidences have reported that periodontitis can be a risk factor for the pathogenesis of various systemic diseases. Porphyromonas gingivalis (Pg), one of the crucial pathogens in chronic periodontitis, has...
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Organoid as a culture system for viral vaccine strains

Hong KJ, Seo SH

Organoid is an in vitro multicellular form mimicking in vivo organ. Its similarity to human organ including cellular organization, molecular expression patterns, as well as genetic signatures enables to study...
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The Present and Future of the Cancer Microenvironment Bioprinting

Cho MJ, Chi BH, Kim MJ, Whang YM, Chang IH

Cancer is the tissue complex consisted with heterogeneous cellular compositions, and microenvironmental cues. During the various stages of cancer initiation, development, and metastasis, cell–cell interactions as well as cell-extracellular matrix...
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A Case of Organoid Nevus on the Knee

Koh JK, Jung S, Hwang S, Seol JE, Kim H, Sung H, Kim YM, Yoon S, Seo JK

  • KMID: 1802087
  • Korean J Dermatol.
  • 2014 Apr;52(4):283-284.
No abstract available.
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Stem cell-based therapy for inflammatory bowel disease

Shimizu H, Suzuki K, Watanabe M, Okamoto R

Inflammatory bowel disease (IBD) is an idiopathic, multi-etiological disease characterized by inflammation and mucosal destruction of the gastrointestinal tract. Despite the remarkable advance in immunomodulating therapies, there still remains a...
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3-Dimensional Culture of Prostate Organoid under Microgravity-Simulated Growth Conditions: Cell-Cell Interactions Favoring Cancer Growth and Progression

Rhee HW, Chung LW

  • KMID: 2289913
  • Korean J Urol.
  • 1999 Sep;40(9):1157-1168.
PURPOSE: Three-dimensional(3-D) organization is critical for both the normal development and, tumor growth and progression. Cell-cell and cell-matrix interactions determine normal prostate development and its subsequent neoplastic transformation. To understand...
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Human ex vivo and in vitro disease models to study food allergy

Hung L, Obernolte , Sewald K, Eiwegger T

Food allergy is a growing global public health concern. As treatment strategies are currently limited to allergen avoidance and emergency interventions, there is an increasing demand for appropriate models of...
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Apocrine Adenocarcinoma and Three Different Benign Skin Tumors Probably Arising in an Organoid Nevus

Hwang SW, Kim HJ, Park CS

We herein present a case of simultaneous occurrence of apocrine adenocarcinoma, syringocystadenoma papilliferum, syringoma, and eccrine hydrocystoma arising in an organoid nevus (nevus sebaceus of Jadassohn) which had been present...
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Sebaceous Carcinoma and Basal Cell Epithelioma Developed in Organoid Nevus

Jang KA, Ahn SJ, Choi JH, Koh JK

In about 20 to 30 percent of cases with organoid nevus (nevus sebaceus), benign and/or ma-al lignant tumors of the epidermis and adnexae may develop. We describe a 71-year-old woman...
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Keratoacanthoma in Co-existence with Nevus Sebaceus

Ahn SW, Chun TJ, Seo SJ, Hong CK

Nevus sebaceus of Jadassohn has been referred to as a organoid nevus that classically evolves through three stages and may be associated with a range of skin tumors, and of...
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A Case of Dilated Pore of Winer

Jang JG, Kim SC, Yoon MS, Chun SI

  • KMID: 1680328
  • Korean J Dermatol.
  • 1989 Feb;27(1):108-111.
We report a case of dilated pare of Winer occuring in a 33-year-oid female patient. Dilated pore belongs to adenoma or organoid group of benign hair differentiation tumors. The patient...
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Generation of Organotypic Multicellular Spheres by Magnetic Levitation: Model for the Study of Human Hematopoietic Stem Cells Microenvironment

Mejía-Cruz CC, Barreto-Durán E, Pardo-Pérez MA, Jimenez MC, Rincón J, Vanegas K, Rodríguez JL, Jaramillo-Garcia LF, Ulloa JC, Díaz RM, Leal-García E, Pérez-Núñez R, Barreto A, Rodríguez-Pardo VM

BACKGROUND AND OBJECTIVE: The characteristics of human hematopoietic stem cells are conditioned by the microenvironment of the bone marrow, where they interact with other cell populations, such as mesenchymal stem...
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Clinical Implementation of Precision Medicine in Gastric Cancer

Jeon J, Cheong JH

Gastric cancer (GC) is one of the deadliest malignancies in the world. Currently, clinical treatment decisions are mostly made based on the extent of the tumor and its anatomy, such...
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Organoid culture of bladder cancer cells

Yoshida T, Singh AK, Bishai WR, McConkey D, Bivalacqua TJ

No abstract available.
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A Case of Sebaceous Adenoma

Lee KY, Kim KJ, Choi YH, Choi KC

  • KMID: 2231531
  • Korean J Dermatol.
  • 1986 Dec;24(6):868-871.
Sebaceous adenoma is a benign organoid tumor of proliferating, incornpletely differentiated sebaceous glands. We report a case of sebaceous adenoma in a 15-year-old male. He had a 1.7 x 2.2...
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A Cases of Nevus Sebaceus of Jandassohn Associated with Tubular Apocrine Adenoma

Chang J, Kim MN, Song KY, Ro BI, Chang CY

  • KMID: 2231287
  • Korean J Dermatol.
  • 1990 Feb;28(1):103-106.
The nevus sebaceus of Jadsssohn is an organoid nevus generally noted on the scalp or the face as a single lesion. A 26-year-old man has suffered from a pea sized,...
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Histopathologic Resemblance of Ovarian Dermoid Cyst to Various Skin Tumors

Hwang SW, Lee KM

BACKGROUND: The wall of ovarian dermoid cysts shows various kinds of morphologic patterns. Some of them resemble the features of epidermal and epidermal appendageal tumors. OBJECTIVE: The purpose of this study...
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Protruding Type of Fibrous Hamartoma of Infancy

Park O, Lee SM, Won CH, Chang SE, Lee MW, Choi JH, Moon KC, Sung KJ

  • KMID: 2247593
  • Korean J Dermatol.
  • 2011 Apr;49(4):357-359.
Fibrous hamartoma of infancy (FHI) is a rare benign soft tissue tumor that is composed of an organoid pattern of fibrous tissue and primitive mesenchyme and adipose tissue. The majority...
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Coincidence of Dermal Melanocyte Hamartoma and Becker's Nevus in a Patient with Neurofibromatosis Type 1

Kim YJ, Choi ME, Lee MW, Choi JH, Chang SE

  • KMID: 2470219
  • Korean J Dermatol.
  • 2019 Dec;57(10):632-634.
Dermal melanocytosis is characterized by an increased number of ovoid to elongated melanocytes situated between collagen fibers in the dermis, including blue nevus, Mongolian spots, nevus of Ota and Ito...
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