Investig Clin Urol.  2018 May;59(3):149-151. 10.4111/icu.2018.59.3.149.

Organoid culture of bladder cancer cells

• Yoshida T
• Singh AK
• Bishai WR
• McConkey D
• Bivalacqua TJ

• KMID: 2410586
• DOI: http://doi.org/10.4111/icu.2018.59.3.149

Abstract

No abstract available.

MeSH Terms

Organoids*
Urinary Bladder Neoplasms*
Urinary Bladder*

Reference

1. Okuyama H, Yoshida T, Endo H, Nakayama M, Nonomura N, Nishimura K, et al. Involvement of heregulin/HER3 in the primary culture of human urothelial cancer. J Urol. 2013; 190:302–310.

2. Yoshida T, Kates M, Sopko NA, Liu X, Singh AK, Bishai WR, et al. Ex vivo culture of tumor cells from N-methyl-N-nitrosourea-induced bladder cancer in rats: development of organoids and an immortalized cell line. Urol Oncol. 2018; 36:160.e23–160.e32.

3. Yoshida T, Sopko NA, Kates M, Liu X, Joice G, McConkey DJ, et al. Three-dimensional organoid culture reveals involvement of Wnt/β-catenin pathway in proliferation of bladder cancer cells. Oncotarget. 2018; 9:11060–11070.

4. Yoshida T, Okuyama H, Nakayama M, Endo H, Nonomura N, Nishimura K, et al. High-dose chemotherapeutics of intravesical chemotherapy rapidly induce mitochondrial dysfunction in bladder cancer-derived spheroids. Cancer Sci. 2015; 106:69–77.

5. Lee SH, Hu W, Matulay JT, Silva MV, Owczarek TB, Kim K, et al. Tumor evolution and drug response in patient-derived organoid models of bladder cancer. Cell. 2018; 173:515–528.

6. Mullenders J, de Jongh E, Brousali A, Roosen M, Jonges T, Meijer R, et al. Urothelial organoids: a novel culture method for bladder cancer. Urol Oncol. 2017; 35:616.

7. Yoshida T, Okuyama H, Nakayama M, Endo H, Tomita Y, Nonomura N, et al. Dynamic change in p63 protein expression during implantation of urothelial cancer clusters. Neoplasia. 2015; 17:574–585.

8. Cheung KJ, Padmanaban V, Silvestri V, Schipper K, Cohen JD, Fairchild AN, et al. Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters. Proc Natl Acad Sci U S A. 2016; 113:E854–E863.

9. Vlachogiannis G, Hedayat S, Vatsiou A, Jamin Y, Fernández-Mateos J, Khan K, et al. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science. 2018; 359:920–926.