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Antimicrobial Effects of Oleanolic Acid, Ursolic Acid, and Sophoraflavanone G against Enterococcus faecalis and Propionibacterium acnes

Jo E, Choi MH, Kim HS, Park SN, Lim YK, Kang CK, Kook JK

  • KMID: 1737500
  • Int J Oral Biol.
  • 2014 Jun;39(2):75-79.
The aim of this study was to investigate antimicrobial effect of oleanolic acid (OA), ursolic acid (UA), and sophoraflavanone G against Enterococcus faecalis and Propionibacterium acnes, which are the major...
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Antimicrobial Effects of Oleanolic Acid against Streptococcus mutans and Streptococcus sobrinus Isolated from a Korean Population

Kim MJ, Kim CS, Ha WH, Kim BH, Lim YK, Park SN, Cho YJ, Kim M, Ko JH, Kwon SS, Ko YM, Kook JK

  • KMID: 1457212
  • Int J Oral Biol.
  • 2010 Dec;35(4):191-195.
Oleanolic acid is a natural triterpenoid that exists widely in foods and some medicinal herbs. The purpose of this study was to determine the antimicrobial activity of oleanolic acid against...
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Effect of oleanolic acid on the activity, secretion and gene expression of matrix metalloproteinase-3 in articular chondrocytes in vitro and the production of matrix metalloproteinase-3 in vivo

Kang DG, Lee HJ, Kim KT, Hwang SC, Lee CJ, Park JS

In the present study, we tried to examine whether oleanolic acid regulates the activity, secretion and gene expression of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well...
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Antimicrobial Activity of Oleanolic Acid, Ursolic Acid, and Sophoraflavanone G against Periodontopathogens

Park SN, Kook JK

  • KMID: 1709608
  • Int J Oral Biol.
  • 2013 Dec;38(4):149-154.
In general, oleanolic acid (OA) and ursolic acid (UA) have antimicrobial effect against Gram-positive bacteria but not Gram-negative bacteria whereas sophoraflavanone G has antimicrobial activity against both bacterial types. However,...
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Enhancement of Platelet Aggregation by Ursolic Acid and Oleanolic Acid

Kim M, Han CH, Lee MY

  • KMID: 2170644
  • Biomol Ther.
  • 2014 May;22(3):254-259.
The pentacyclic triterpenoid ursolic acid (UA) and its isomer oleanolic acid (OA) are ubiquitous in food and plant medicine, and thus are easily exposed to the population through natural contact...
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Studies on the Chemical Constituents from the Seeds of Zizyphus jujuba var. inermis

Lee NK, Shin HJ, Kim WS, In G, Han CK

This study analyzed the seeds of Zizyphus jujuba var. inermis commonly used as a remedy in traditional Chinese medicine, in order to determine its various biologically active compounds. Through process...
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Oleanolic acid induced autophagic cell death in hepatocellular carcinoma cells via PI3K/Akt/mTOR and ROS-dependent pathway

Shi Y, Song Q, Hu D, Zhuang X, Yu S, Teng D

Oleanolic acid (OA) has a wide variety of bioactivities such as hepatoprotective, anti-inflammatory and anti-cancer activity and is used for medicinal purposes in many Asian countries. In the present study,...
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The Cytotoxic Constituents of Betula platyphylla and their Effects on Human Lung A549 Cancer Cells

Yang EJ, An JH, Son YK, Yeo JH, Song KS

During the screening for cytotoxic compounds from plants grown in Korea, Betula platyphylla (BP) showed potent activity against the adenocarcinomic human alveolar basal epithelial A549 cell line. To identify the...
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Antishigellosis and Cytotoxic Potency of Crude Extracts and Isolated Constituents from Duranta repens

Nikkon F, Habib MR, Karim MR, Hossain MS, Mosaddik M, Haque ME

The crude ethanol extracts (stem and fruits), their fractions and two triterpenes, beta-Amyrin and 12-Oleanene 3beta, 21beta-diol, isolated as a mixture from the chloroform soluble fraction of an ethanolic extract...
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Protective effect of total aralosides of Aralia elata (Miq) Seem (TASAES) against diabetic cardiomyopathy in rats during the early stage, and possible mechanisms

Xi S, Zhou G, Zhang X, Zhang W, Cai L, Zhao C

Total aralosides of Aralia elata (Miq) Seem (TASAES) from Chinese traditional herb Longya Aralia chinensis L was found to improve cardiac function. The present study was to determine the protective...
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