- Dissecting the molecular mechanism of nuclear receptor action: transcription coactivators and corepressors
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Lee JW, Cheong JH, Lee YC, Na SY, lee SK
- KMID: 1109302
- Exp Mol Med.
- 2000 Jun;32(2):53-60.
No abstract available. -
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- Neuroprotection Signaling of Nuclear Akt in Neuronal Cells
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Ahn JY
- KMID: 2165523
- Exp Neurobiol.
- 2014 Sep;23(3):200-206.
- doi: 10.5607/en.2014.23.3.200
Akt is one of the central kinases that perform a pivotal function in mediating survival signaling in a wide range of neuronal cell types in response to growth factor stimulation.... -
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- The Elevated Expression of the High Mobility Group-I(Y) Proteins in Thyroid Cancer using Semi-Quantitation RT-PCR
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Ryu JW, Kim SJ
- KMID: 2206271
- J Korean Surg Soc.
- 1998 Jan;54(1):23-27.
High Mobility Group I(HMG-I) proteins are nuclear proteins that are required for induction of the human IFN-beta gene by virus and for the regulation of the tumor necrosis-beta factor and... -
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- Expression of p21, p53 and bcl-2 Proteins in Invasive Ductal Carcinoma of the Breast
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Jo HJ, Yun KJ, Moon HB
- KMID: 1979367
- Korean J Pathol.
- 2003 Dec;37(6):393-399.
BACKGROUND: This study was designed to investigate the prognostic significance of p21, p53, and bcl-2 proteins in invasive ductal carcinoma of the breast. METHODS: Seventy-two cases of invasive ductal carcinoma... -
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- Usefulness of Nuclear Protein in Testis (NUT) Immunohistochemistry in the Cytodiagnosis of NUT Midline Carcinoma: A Brief Case Report
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Park HS, Bae YS, Yoon SO, Lim BJ, Hong HJ, Ro JY, Hong SW
- KMID: 1719573
- Korean J Pathol.
- 2014 Aug;48(4):335-338.
- doi: 10.4132/KoreanJPathol.2014.48.4.335
No abstract available. -
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- O-GlcNAc Modification: Friend or Foe in Diabetic Cardiovascular Disease
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Karunakaran U, Jeoung NH
- KMID: 2029873
- Korean Diabetes J.
- 2010 Aug;34(4):211-219.
- doi: 10.4093/kdj.2010.34.4.211
O-Linked beta-N-acetyl glucosaminylation (O-GlcNAcylation) is a dynamic post-translational modification that occurs on serine and threonine residues of cytosolic and nuclear proteins in all cell types, including those involved in the... -
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- Morphological and biochemical analysis of anti-nuclear matrix protein antibodies in human sera
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Yu E, Lee H, Oh W, Yu B, Moon H, Lee I
- KMID: 1062193
- J Korean Med Sci.
- 1999 Feb;14(1):27-33.
- doi: 10.3346/jkms.1999.14.1.27
Autoimmune sera have been used in the diagnosis of autoimmune diseases as well as the analysis of nuclear substructures. In an attempt to study the biological characteristics of the nuclear... -
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- Expression of p53 and MDM2 Proteins in Thyroid Carcinomas
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Lee CH
- KMID: 2037282
- Korean J Pathol.
- 1998 Apr;32(4):255-260.
The nuclear protein p53 is a tumor suppressor gene product that functions in pathways of cell cycle control and in the repair of damaged DNA. The MDM2 gene codes for... -
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- Expression and roles of NUPR1 in cholangiocarcinoma cells
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Kim KS, Jin DI, Yoon S, Baek SY, Kim BS, Oh SO
- KMID: 1447449
- Anat Cell Biol.
- 2012 Mar;45(1):17-25.
- doi: 10.5115/acb.2012.45.1.17
Nuclear protein-1 (NUPR1) is a small nuclear protein that is responsive to various stress stimuli. Although NUPR1 has been associated with cancer development, its expression and roles in cholangiocarcinoma have... -
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- The Assessment of Proliferating Cell Nuclear Antigen (PCNA) in Cervical Tumors
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Kim SN, Park TK, Song KC, Kim HG, Park CI
- KMID: 2245109
- Korean J Gynecol Oncol Colposc.
- 1994 Jun;5(2):1-9.
Proliferating cell nuclear ntigen (FCNA) iis a nuclear protein that is syntheaimd in late Gl and S phases of cell cycle and is correlated with the cell proliferative stale. The... -
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- Detection of O-Linked-N-Acetylglucosamine Modification and Its Associated Enzymes in Human Degenerated Intervertebral Discs
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Nikolaou G, Zibis AH, Fyllos AH, Katsioulis A, Sotiriou S, Kotrotsios A, Sgantzos M, Vassiou A, Arvanitis
- KMID: 2397623
- Asian Spine J.
- 2017 Dec;11(6):863-869.
- doi: 10.4184/asj.2017.11.6.863
STUDY DESIGN: Human herniated discs were obtained from discectomy specimens for the immunohistochemical detection of O-GlcNAc and O-GlcNAcase (OGA)/O-GlcNAc transferase (OGT). PURPOSE: This study aimed to quantify the extent of O-GlcNAcylation... -
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- Prognostic significance of proliferating cell nuclear antigen-positive growth fraction in gastric adenomas
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Kim WH, Choi GY, Kim YI
- KMID: 1421915
- J Korean Med Sci.
- 1992 Sep;7(3):199-203.
- doi: 10.3346/jkms.1992.7.3.199
The proliferative activity of gastric adenomas from 18 patients (42 endoscopic procedures) was compared with follow-up results. These cases were gastric adenomas proven by follow-up with repeated endoscopic procedures... -
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- Screening and Cloning of Genes Preferentially Expressed in Aminopterin-Treated Myeloma Cell Apoptosis
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Lee HC, Kim SJ, Yoon S, Kwon SJ, Chung YH
- KMID: 2175032
- J Korean Cancer Assoc.
- 2000 Jun;32(3):655-664.
PURPOSE: When murine myeloma cells P3-X63-Ag8.653 (V653) of this model treated with amin opterin, an anticancer drug, they can't synthesize nucleic acid via de novo or salvage pathway and selectively eliminated due... -
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- Immunohistochemical detection of p53 protein, c-erbB-2 protein, epidermal growth factor receptor protein and proliferating cell nuclear antigen in gastric carcinoma
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Jang WI, Yang WI, Lee CI, Kim HS, Song KS, Cho MY, Park JK, Shim YH
- KMID: 2157514
- J Korean Med Sci.
- 1993 Aug;8(4):293-304.
- doi: 10.3346/jkms.1993.8.4.293
There is increasing evidence that genes involved in normal cell growth and differentiation (oncogenes) or genes that encode for growth factors are important in determining the development and biologic aggressiveness... -
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- Comparison of bromodeoxyuridine and proliferating cell nuclear antigen labeling in gastric carcinoma
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Kang SM, Kim WH, Kim CW, Kim YI
- KMID: 1422181
- J Korean Med Sci.
- 1994 Feb;9(1):16-20.
- doi: 10.3346/jkms.1994.9.1.16
The proliferative activity of human gastric carcinoma was measured by means of in vitro incorporation of the thymidine analogue, 5-bromo-2'-deoxyuridine (BrdU), into the newly-synthesized DNA of fresh tumors and immunohistochemical... -
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- Pathogenesis and Management of Serrated Polyps: Current Status and Future Directions
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Anderson J
- KMID: 2070073
- Gut Liver.
- 2014 Nov;8(6):582-589.
- doi: 10.5009/gnl14248
Hyperplastic or serrated polyps were once believed to have little to no clinical significance. A subset of these polyps are now considered to be precursors to colorectal cancers (CRC) in... -
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- Two Cases of Nuclear Protein in Testis Midline Carcinomas of Sinonasal Tract
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Lee M, Kang YS, Won TB, Kim HJ
- KMID: 2401409
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2017 Dec;60(12):673-677.
- doi: 10.3342/kjorl-hns.2016.17272
Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare and aggressive tumor that is genetically characterized by chromosomal rearrangement of the NUT gene. NMC predominantly involves the midline... -
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- Langerhans cell protein 1 (LCP1) binds to PNUTS in the nucleus: implications for this complex in transcriptional regulation
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Lee SJ, Lee JK, Maeng YS, Kim YM, Kwon YG
- KMID: 1123466
- Exp Mol Med.
- 2009 Mar;41(3):189-200.
- doi: 10.3858/emm.2009.41.3.022
Protein phosphatase-1 (PP1) nuclear targeting subunit (PNUTS), also called PP1R10, p99, or CAT 53 was originally isolated as a mammalian nuclear PP1-binding protein. In this study, we performed yeast two-hybrid... -
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- Comparison of brain tumor growth kinetics by proliferating cell nuclear antigen (PCNA) and bromodeoxyuridine (BrdU) labeling
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Lee KS, Yang WI
- KMID: 1120238
- Yonsei Med J.
- 1992 Sep;33(3):265-271.
- doi: 10.3349/ymj.1992.33.3.265
The bromodeoxyuridine (BrdU) labeling study provides valuable cell kinetic information for individual tumors that could suggest the prognosis of each patient who had a tumor. Recently, a monoclonal antibody against... -
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- Current Understanding of HMGB1-mediated Autophagy
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Kwak MS, Shin JS
- KMID: 2168685
- J Bacteriol Virol.
- 2013 Jun;43(2):148-154.
- doi: 10.4167/jbv.2013.43.2.148
Reactive oxygen species (ROS) is an oxidative stress to which cells respond by activating various defense mechanisms or cell death. Autophagy associated with oxidative stress response is a process to... -
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