- Spinal Nitric Oxide Synthase Type II Increases Neurosteroid-metabolizing Cytochrome P450c17 Expression in a Rodent Model of Neuropathic Pain
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Choi SR, Beitz AJ, Lee JH
- KMID: 2458549
- Exp Neurobiol.
- 2019 Aug;28(4):516-528.
- doi: 10.5607/en.2019.28.4.516
We have previously demonstrated that the neurosteroid dehydroepiandrosterone sulfate (DHEAS) induces functional potentiation of N-methyl-D-aspartate (NMDA) receptors via increases in phosphorylation of NMDA receptor GluN1 subunit (pGluN1). However, the modulatory... -
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- Inhibitory Effect of a Sesquiterpene from Artemisia iwayomogi on Expression of Inducible Nitric Oxide Synthase by Suppression of I-κBα Degradation in LPS-stimulated RAW 264.7 Cells
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Kim NY, Koh HJ, Li H, Lee HJ, Ryu JH
- KMID: 2387057
- Nat Prod Sci.
- 2017 Jun;23(2):92-96.
- doi: 10.20307/nps.2017.23.2.92
A sesquiterpene was purified from Artemisia iwayomogi methanolic extract during the course of searching anti-inflammatory principle from medicinal plants. A sesquiterpene identified as armefolin inhibited the production of nitric oxide... -
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- Inducible Nitric Oxide Synthase (iNOS) Expression in the Hypoxic Injury to Pancreatic Beta (MIN6) Cells
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Ko SH, Kim SB, Ryu KR, Kim JW, Ahn YB, Moon SD, Kim SR, Lee JM, Kwon HS, Yoon KH, Song KH
- KMID: 2008263
- J Korean Diabetes Assoc.
- 2006 Sep;30(5):336-346.
- doi: 10.4093/jkda.2006.30.5.336
BACKGROUND: Islet transplantation is an alternative potential strategy to cure type 1 diabetes mellitus. However, two or more donors are usually needed for one recipient because a substantial part of... -
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- The Effect of Hypothermia on Lung Inducible Nitric Oxide Synthase Gene Expression in Intestinal Ischemia-Reperfusion Injury
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Kim K, Lee JH, Suh GJ, Youn YK, Kang YJ, Kim MA, Cho SK, Shin HK
- KMID: 2096952
- J Korean Soc Traumatol.
- 2006 Jun;19(1):14-20.
PURPOSE: Although hypothermia has been used in many clinical situations, such as post cardiopulmonary resuscitation, stroke, traumatic brain injury, septic shock, and hemorrhagic shock, the mechanism by which it works... -
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- Nitric oxide production and inducible nitric oxide synthase expression induced by Porphyromonas gingivalis lipopolysaccharide
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Paek EY, Choi EY, Choi JI, Lee JY, Kim SJ
- KMID: 1999714
- J Korean Acad Periodontol.
- 2005 Dec;35(4):1081-1095.
- doi: 10.5051/jkape.2005.35.4.1081
No abstract available. -
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- Correlation Between Neuronal Apoptosis and Expression of Inducible Nitric Oxide Synthase after Transient Focal Cerebral Ischemia
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Yi BY, Hwang SK, Kang KS, Quan HH, Lee YM, Kim JW, Kwak EK, Park JY, Sohn YK
- KMID: 2277690
- Korean J Pathol.
- 2004 Dec;38(6):364-371.
BACKGROUND: Neuronal death in acute-phase cerebral ischemic injury is caused by necrosis. However, neuronal injury after reperfusion can be associated with apoptosis. METHODS: We used Sprague-Dawley rats whose brains were... -
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- The Effect of Sevoflurane and Propofol on Expression of Inducible Nitric Oxide Synthase in Endotoxemic Rats
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Kim CH, Park JH, Baek SH, Baik SW
- KMID: 2228517
- Korean J Crit Care Med.
- 2004 Dec;19(2):106-114.
BACKGROUND: It is a well-known phenomenon that alveolar and peritoneal macrophages exposed to bacterial lipopolysaccharide (LPS) induce a large output of nitric oxide (NO) and an inducible nitric oxide synthase... -
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- Inhibitory Effect of Inducible Nitric Oxide Synthase Gene Transfer on Intimal Hyperplasia and Fibronectin Expression Induced by Carotid Artery Denudation
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Kye BH, Hong SY, Yang KH, Park SC, Park JS
- KMID: 1941030
- J Korean Soc Vasc Surg.
- 2004 Dec;20(2):192-199.
PURPOSE: Intimal hyperplasia is a pathologic condition that is commonly observed with the atherosclerotic change of blood vessels; this condition is usually observed after arterial operation and interventions such as... -
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- Inhibition of Inducible Nitric Oxide Synthase Expression by YS 49, a Synthetic Isoquinoline Alkaloid, in ROS 17/2.8 Cells Activated with TNF-alpha, IFN-gamma and LPS
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Kang YJ, Kang SY, Lee YS, Park MK, Kim HJ, Seo HG, Lee JH, Yun-Choi H, Chang KC
- KMID: 1611431
- Korean J Physiol Pharmacol.
- 2004 Oct;8(5):273-280.
Nitric oxide (NO) has been suggested to act as a mediator of cytokine-induced effects of turn over of bone. Activation of the inducible nitric oxide synthase (iNOS) by inflammation has... -
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- Expression of Tumor Necrosis Factor-alpha, Interleukin-1beta and Inducible Nitric Oxide Synthase after Stereotaxic Injection of Lipopolysaccharide in Rat Hippocampus
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Oh HK, Kang KS, Kim JY, Kwak EK, Kim JW, Park JY, Sohn YK
- KMID: 2275496
- Korean J Pathol.
- 2004 Jun;38(3):157-164.
BACKGROUND: Brain inducible nitric oxide synthase (iNOS) might be detectable in several pathologic conditions, and it is thought to play an important role in their pathophysiology. Tumor necrosis factor (TNF)-alpha... -
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- Expression of Inducible Nitric Oxide Synthase (iNOS, NOS2) in Osteosarcoma Correlates with Prognosis
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Jeong J, Kim HS, Kang YK, Kim HS, Lee SH
- KMID: 2399067
- J Korean Orthop Assoc.
- 2003 Oct;38(6):641-645.
PURPOSE: This study was performed to investigate the expression pattern of inducible nitric oxide synthase (iNOS) in osteosarcoma and to determine whether its expression correlates with metastatic potential and prognosis.... -
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- Effect of Inducible Nitric Oxide Synthase Inhibitor on Apoptosis in Hypoxic-Ischemic Injury of the Neonatal Rat Brain: 1H Magnetic Resonance Spectroscopy Study
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Hwang HS, Bang JY, Park PH
- KMID: 2239929
- Korean J Anesthesiol.
- 2003 Sep;45(3):393-401.
- doi: 10.4097/kjae.2003.45.3.393
BACKGROUND: Inducible nitric oxide synthase (iNOS) is expressed during the late stage of ischemia and may play an important role in the delayed progression of ischemic brain injury. This study... -
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- Inducible Nitric Oxide Synthase (iNOS) is Increased in Diabetic Rat Glomeruli: Role of Angiotensin II (AII)
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Choi KH, Noh H, Kim BS, Kang SW, Han DS, Lee HY
- KMID: 1610172
- Korean J Nephrol.
- 2003 Jul;22(4):366-373.
BACKGROUND: This study was designed to examine whether iNOS pathway is pathologically altered in experimental diabetic nephropathy and whether therapy with ACE inhibitor (imidapril: I) or angiotensin II type 1... -
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- Expression of Cyclooxygenase-2 and Inducible Nitric Oxide Synthase in Colorectal Cancer
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Yang KH, Bae BN, Kim JY, Kim KH, Han SH, Kim HJ, Kim YD, Kim HY, Kim SJ
- KMID: 2025800
- J Korean Soc Coloproctol.
- 2003 Jun;19(3):144-150.
PURPOSE: Recently, it has been recognized that both cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) produce important endogeneous factors of human tumor progression. The aims of this study is... -
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- Hemodynamic Change and Hypoxic Inducible Factor-1alpha and Inducible Nitric Oxide Synthase Expression of Ipsilateral Kidney during Acute Stage of Ureteropelvic Junction Obstruction in Adult Rat
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Lee SD, Lee CH, Choi EH
- KMID: 2293340
- Korean J Urol.
- 2003 May;44(5):481-489.
Purpose: This study aimed to evaluate the expression of inducible nitric oxide synthase (iNOS) and hypoxic inducible factor-1alpha (HIF-1alpha) and the hemodynamic changes in the renal medulla and cortex, during... -
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- Expression of Inducible Nitric Oxide Synthase (iNOS) in the Epithelial Cells of the Distended Bile Duct by the Bile Ductal Ligation
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Park SS, Jin GB, Park JW, Jang LC, Sung RH, Choi JW
- KMID: 2004555
- J Korean Surg Soc.
- 2003 May;64(5):365-371.
PURPOSE: Recent studies in an obstructive jaundice rat model showed that the bile duct epithelium is also very important in the bile duct dilatation besides the increased luminal pressure. This... -
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- The Role of Inducible Nitric Oxide Synthase in the Development of Nasal Hyper-responsiveness of the Rhinosinusitis Rat Model
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Kim JP, Jeon SY, Ahn SK, Hwang WH, Sung BG, Kim EA
- KMID: 2275965
- Korean J Otolaryngol-Head Neck Surg.
- 2003 Jan;46(1):35-41.
BACKGROUND AND OBJECTIVES: Hyper-responsiveness to nonspecific stimuli is a characteristic finding of all allergic diseases. It is probably due to eosinophil infiltration, release of cytotoxic proteins, and epithelial damage in... -
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- Role of Inducible Nitric Oxide Synthase as a Mediator of Renal Ischemia/Reperfusion Injury in the Rat
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Moon KH, Cho CK, Jung HC, Park TC, Choi HC, Kim YJ, Choi TS
- KMID: 2292527
- Korean J Urol.
- 2002 Dec;43(12):1070-1077.
PURPOSE: This study was undertaken to elucidate if nitric oxide (NO), produced by inducible nitric oxide synthase (iNOS) following renal ischemia/reperfusion (I/R), contributes to renal injury in rats, and if... -
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- Expression of Inducible Nitric Oxide Synthase and Nitric Oxide Mediated Apoptosis in Neuronal PC12 Cells after Lipopolysaccharide/Tumor Necrosis Factor-/Interferon- Treatment
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Kim J, Kim J, Kang K, Kwak E, Park J, Park T, Sohn Y
- KMID: 1725913
- Korean J Pathol.
- 2002 Aug;36(4):249-256.
BACKGROUND: Inducible nitric oxide synthase (iNOS) has been detected in a number of pathologic conditions in the central nervous system. This study was investigated the patterns of iNOS expression in... -
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- Inhibitory Effects of Paeonia Suffruticosa on the Expression of Inducible Nitric Oxide Synthase Gene in RAW264.7 Macrophages
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Son SY, Sul CK, Onyango I
- KMID: 2292466
- Korean J Urol.
- 2002 Jun;43(6):480-485.
PURPOSE: The aim of the present study was to examine the effect of the root cortex of Paeonia suffruticosa, an anti-inflammatory folk medicine, on nitric oxide (NO) synthesis and the... -
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