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The Role of Visfatin in Diabetic Nephropathy

Kang YS, Cha DR

As a result of the energy overload in obesity, insulin resistance, type 2 diabetes, dyslipidemia, hypertension, and atherosclerosis develop, which together comprise the metabolic syndrome. Although the kidney becomes a...
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Inhibition of Nicotinamide Phosphoribosyltransferase Induces Apoptosis in Estrogen Receptor-Positive MCF-7 Breast Cancer Cells

Alaee M, Khaghani S, Behroozfar K, Hesari Z, Ghorbanhosseini SS, Nourbakhsh M

PURPOSE: Tumor cells have increased turnover of nicotinamide adenine dinucleotide (NAD⁺), the main coenzyme in processes including adenosine diphosphate-ribosylation, deacetylation, and calcium mobilization. NAD⁺ is predominantly synthesized in human cells...
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Elevated Serum Levels of Visfatin in Patients with Henoch-Schonlein Purpura

Cao N, Chen T, Guo ZP, Li MM, Jiao XY

  • KMID: 2368149
  • Ann Dermatol.
  • 2014 Jun;26(3):303-307.
BACKGROUND: Henoch-Schonlein purpura (HSP) is an immune complex-mediated disease predominantly characterized by the deposition of circulating immune complexes containing immunoglobulin A (IgA) on the walls of small vessels. Although the...
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Association of Adipokines with Development and Progression of Nonalcoholic Fatty Liver Disease

Boutari C, Perakakis , Mantzoros

Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease affecting 30% of the general population and 40% to 70% of obese individuals. Adipose tissue plays a crucial role in...
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Clinical Utility of Pre-B-Cell Colony-Enhancing Factor in Bronchoalveolar Lavage Fluid of Acute Critical Ill Patients with Lung Infiltrates

Lee K, Hong SB

  • KMID: 2319276
  • Tuberc Respir Dis.
  • 2009 Nov;67(5):402-408.
BACKGROUND: Pre-B-cell colony enhancing factor (PBEF) has been suggested as a novel biomarker in sepsis and acute lung injury. We measured the PBEF in bronchoalveolar lavage (BAL) fluid of acute...
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NAMPT enzyme activity regulates catabolic gene expression in gingival fibroblasts during periodontitis

Park KH, Kim DK, Huh YH, Lee G, Lee SH, Hong Y, Kim SH, Kook MS, Koh JT, Chun JS, Lee SE, Ryu JH

Periodontal disease is one of the most prevalent chronic disorders worldwide. It is accompanied by inflammation of the gingiva and destruction of periodontal tissues, leading to alveolar bone loss. Here,...
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Adipokines, the obesity and metabolic complications in the postmenopausal women

Lee SW, Kim MR, You YO

  • KMID: 2273810
  • Korean J Obstet Gynecol.
  • 2009 Dec;52(12):1204-1211.
During the menopausal transition there are changes in body fat and its disrtribution, and central adiposity is associated with the metabolic complications such as insulin resistance and dyslipidemia. Adipose tissue is...
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Obesity Associated Hypertension: New Insights into Mechanism

Kang YS

With excess nutrition, the burden of obesity is a growing problem worldwide. The imbalance between energy intake and expenditure leads to variable disorders as all major risk factors for cardiovascular...
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Meta-analysis of Circulating Adiponectin, Visfatin, and Ghrelin Levels in Patients with Systemic Lupus Erythematosus

Lee YH, Song GG

OBJECTIVE: To evaluate the association between circulating adiponectin, visfatin, and ghrelin levels and systemic lupus erythematosus (SLE). METHODS: We conducted a meta-analysis to compare serum/plasma adiponectin, visfatin, and ghrelin levels in...
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Gingival crevicular fluid levels of visfatin in patients with chronic periodontitis and polycystic ovary syndrome

Saljoughi , Nasri K, Bayani M

OBJECTIVE: Recently, the association between periodontal diseases and polycystic ovary syndrome (PCOS) has been established, and it has been revealed that visfatin levels increase in chronic periodontitis (CP) and PCOS....
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Serum visfatin levels in non-obese women with polycystic ovary syndrome and matched controls

Kim JJ, Choi YM, Hong MA, Kim MJ, Chae SJ, Kim SM, Hwang KR, Yoon SH, Ku SY, Suh CS, Kim SH

OBJECTIVE: The purpose of the current study was to compare the circulating levels of visfatin between women with polycystic ovary syndrome (PCOS) and those without PCOS and to assess the...
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Long-term study of the association of adipokines and glucose variability with diabetic complications

Cha JJ, Min HS, Kim K, Lee MJ, Lee MH, Kim JE, Song HK, Cha DR, Kang YS

BACKGROUND/AIMS: Recent studies have suggested an important role of adipokines in the development of insulin resistance and diabetes mellitus. The clinical relevance of adipokines on long-term outcomes in patients with...
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The Relationship between Plasma Visfatin Level, Obesity and Metabolic Syndrome in Women Without Diabetes

Kim JH, Cho GJ, Choi KM, Han JH, Yoon D, Kim SM

  • KMID: 2270812
  • Korean J Obes.
  • 2009 Mar;18(1):15-23.
BACKGROUND: Visfatin is known to be secreted from visceral adipose tissue and have insulin-mimetic effect. Therefore, visfatin is considered to be related to obesity, especially central obesity, insulin resistance and...
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Change of Circulating Leptin, Adiponectin, Resistin, and Visfatin Level after Treatment of Patients with Active Inflammatory Bowel Disease

Hwangbo Y, Kim HJ, Shim J, Jang JY, Dong SH, Kim BH, Chang YW

BACKGROUND/AIMS: The aim of this study was to evaluate the change in circulating levels of adipokines, including leptin, adiponectin, resistin, and visfatin, after induction therapy of patients with active inflammatory...
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Effects of Sodium Intake on the Association between the Salt-Sensitive Gene, Alpha-Adducin 1 (ADD1), and Inflammatory Cytokines in the Prevalence of Children Obesity

Park MY, Lee MS

OBJECTIVE: To examine the effects of sodium intake on the correlations between the salt-sensitive gene α-adducin 1 (ADD1) and inflammatory cytokines in Korean childhood obesity. METHODS: A total of 2,070 students...
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Relationship between AHI and Insulin Resistance, Serum Adiponectin, and Visfatin

Suh YS, Ahn BH, Hwang SH, Cho YW

  • KMID: 1485445
  • Korean J Obes.
  • 2008 Jun;17(2):65-72.
BACKGROUND: Obstructive sleep apnea (OSA) is closely related to insulin resistance. Adipocytokines, adiponectin and visfatin, may induce the development of insulin resistance among OSA patients. Therefore, we examined the relationships...
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The Effect of Onion Peel Extract on Inflammatory Mediators in Korean Overweight and Obese Women

Kim KA, Yim JE

Quercetin, found abundantly in onion peel, has been known to have antioxidant and anti-obesity effects and improves endothelial function. The purpose of this study was to evaluate the effects of...
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The Relationship of Plasma Visfatin Level and Anorexia in Terminal Cancer Patients

Lee SJ, Lee JY, Choi YS, Lee JY

PURPOSE: Anorexia is a common symptom in terminal cancer patients. Some data have suggested a role of visfatin in regulating feeding behavior. We studied the relationship of a serum visfatin...
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Association of Adipokines, Insulin Resistance, Hypertension and Dyslipidemia in Patients with Psoriasis Vulgaris

Coban M, Tasli L, Turgut S, Ozkan S, Tunc Ata M, Akin F

BACKGROUND: Systemic inflammation in psoriasis causes insulin resistance and cardiovascular diseases. Adipokines are adipose-tissue-derived factors that are involved in metabolic processes. It is thought that these adipokines are associated with...
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Serum Visfatin and Fetuin-A Levels and Glycemic Control in Patients with Obese Type 2 Diabetes Mellitus

Gunduz FO, Yildirmak , Temizel M, Faki Y, Cakmak M, Durmuscan , Sezgin F

BACKGROUND: Visfatin is an adipokine produced by visceral adipose tissue and has insulin-mimicking effects. Fetuin-A is a hepatic secretory protein that binds the insulin receptor and inhibits insulin action both...
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