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Irreversible Parkinsonism due to Acute Organophosphate Intoxication

Kwak JG, Kwon SB, Jung HW, Lee HE, Jung S, Hwang SH

  • KMID: 1572471
  • J Korean Neurol Assoc.
  • 2006 Jun;24(3):298-300.
Only a few case studies describe reversible parkinsonism after organophosphate poisoning and their brain imagings are found to be normal. However, we experienced chronic, irreversible parkinsonism by acute organophosphate poisoning...
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The First Outbreak of Botulism in Korea

Chung GT, Kang DH, Yoo CK, Choi JH, Seong WK

  • KMID: 1611062
  • Korean J Clin Microbiol.
  • 2003 Sep;6(2):160-163.
Botulism is a rare neuroparalytic disease caused by neurotoxins of Clostridium species. A ten-year-old girl and her mother were admitted to a hospital with symptoms of progressive dizziness, blurred vision,...
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Acute Cerebral Infarction after FK 506 Administration in a Kidney Transplantation Recipient: A Case Report

Lim JK, Byun WM, Kim JW

FK506 is widely used as a potent immunosuppressive agent following organ transplantation. However, the use of FK506 is associated with a wide spectrum of neurotoxicity. FK506-induced cerebral infarctions have rarely...
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Occupational Neurologic Disorders in Korea

Kim Y, Jeong KS, Yun YH, Oh MS

This article presents a schematic review of the clinical manifestations of occupational neurologic disorders in Korea and discusses the toxicologic implications of these conditions. Vascular encephalopathy, parkinsonism, chronic toxic encephalopathy,...
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A Case of Hemoperitoneum due to Spontaneous Rupture of Visceral Artery Aneurysm after Ingestion of Puffer Fish

Lee DW, Kim HK, Lee HJ, Hong JM, Kwon JY

Ingestion of puffer fish can cause intoxication, which produces a wide range of symptoms due to the presence of neurotoxins, such as tetrodotoxin, in puffer fish. Abdominal pain is just...
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Paralytic Shellfish Poisoning by Saxitoxin: Two case reports

Choi SC, Park JS, Jung YS

  • KMID: 2331331
  • J Korean Soc Emerg Med.
  • 2001 Dec;12(4):518-522.
Paralytic shellfish poisoning results from consumption of mollusks that have fed on dinoflagellates capable of producing neurotoxins such as saxitoxin. The saxitoxin is concentrated in the shellfish and acts by...
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Botulism

Kim JS

Botulism is a life threatening disorder caused by a neurotoxin produced from the anaerobic, spore-forming bacterium Clostridium botulinum. There are seven antigenically distinct types of botulinum neurotoxins (types A through...
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Toxic Encephalopathy

Kim Y, Kim JW

  • KMID: 2317069
  • Saf Health Work.
  • 2012 Dec;3(4):243-256.
This article schematically reviews the clinical features, diagnostic approaches to, and toxicological implications of toxic encephalopathy. The review will focus on the most significant occupational causes of toxic encephalopathy. Chronic...
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Clostridium botulinum spores in Polish honey samples

Grenda T, Grabczak M, Sieradzki , Kwiatek K, Pohorecka , Skubida M, Bober A

The aim of this study was an examination of 240 multifloral honey samples collected from Polish apiaries to determine Clostridium botulinum occurrence. Honey was collected from apiaries directly after the...
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Exploring the Potential of Flunarizine for Cisplatin-Induced Painful Uremic Neuropathy in Rats

Muthuraman A, Singla SK, Peters A

  • KMID: 2232807
  • Int Neurourol J.
  • 2011 Sep;15(3):127-134.
PURPOSE: The present study was designed to explore the potential of flunarizine for cisplatin induced painful uremic neuropathy in rats. METHODS: Cisplatin (2 mg/kg; i.p., for 5 consecutive days) was administered...
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Temporal Lobe Epilepsy by Insulinoma: A Case of Persistent Abnormalities in Post-Operative EEG

Choi HK, Kim JG

  • KMID: 2340449
  • J Korean Neuropsychiatr Assoc.
  • 2000 Mar;39(2):456-462.
Authors experienced a case of insulinoma which was initially misdiagnosed as idopathic temporal lobe epilepsy with automatism. This patients did not show other hypoglycemic symptoms except seizure. It has been...
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Occupational Neurotoxic Diseases in Taiwan

Liu CH, Huang CY, Huang CC

  • KMID: 2317070
  • Saf Health Work.
  • 2012 Dec;3(4):257-267.
Occupational neurotoxic diseases have become increasingly common in Taiwan due to industrialization. Over the past 40 years, Taiwan has transformed from an agricultural society to an industrial society. The most...
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Promoting Effect of Hydrogen Peroxide on 1-Methyl-4-phenylpyridinium-induced Mitochondrial Dysfunction and Cell Death in PC12 Cells

Lee DH, Lee CS

  • KMID: 1512942
  • Korean J Physiol Pharmacol.
  • 2006 Feb;10(1):51-58.
The promoting effect of hydrogen peroxide (H2O2) against the cytotoxicity of 1-methyl-4-phenylpyridinium (MPP+) in differentiated PC12 cells was assessed by measuring the effect on the mitochondrial membrane permeability. Treatment of...
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Clinical Analysis of Puffer Fish Poisoning Cases

Hyun SH, Sohn CH, Ryoo SM, Oh BJ, Lim KS

  • KMID: 2101642
  • J Korean Soc Clin Toxicol.
  • 2011 Dec;9(2):95-100.
PURPOSE: Ingestion of puffer fish can be poisonous due to the presence of potent neurotoxins such as tetrodotoxin (TTX) found in its tissues. There are few clinical reports related to...
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Insecticidal Activity of Ethyl Acetate Extracts from Culture Filtrates of Mangrove Fungal Endophytes

Abraham S, Basukriadi A, Pawiroharsono S, Sjamsuridzal W

In the search for novel potent fungi-derived bioactive compounds for bioinsecticide applications, crude ethyl acetate culture filtrate extracts from 110 mangrove fungal endophytes were screened for their toxicity. Toxicity tests...
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Effects of Carbon Monoxide Poisoning on Nitric Oxide Synthase Containing Neurons in Rat Brain

Han SH

  • KMID: 2016239
  • J Korean Neurol Assoc.
  • 1997 Aug;15(4):719-727.
Acute carbon monoxide (CO) poisoning primarily affects the central nervous system(CNS), and survivors of severe CO poisoning often suffer permanent neuropsychiatric sequelae. The most widely recognized long-term sequelae of acute...
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Modeling Parkinson's disease in the common marmoset (Callithrix jacchus): overview of models, methods, and animal care

Yun JW, Ahn JB, Kang BC

The common marmoset (Callithrix jacchus) is a small-bodied, popular New World monkey and is used widely in reproductive biology, neuroscience, and drug development, due to its comparative ease of handling,...
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Increased Poly (ADP-ribose) Polymerase Activation in the 6-Hydroxydopamine Induced Dopaminergic Neuronal Cell Death

Kang JH, Kang SY, Park SY, Kang HK, Park DB, Lee YK, Koh JY

  • KMID: 2343084
  • J Korean Neurol Assoc.
  • 2004 Aug;22(4):352-359.
BACKGROUND: The pathological hallmark of Parkinson's disease (PD) is dopaminergic cell death in the substantia nigra (SN), but the cause of cell death is unknown. 6-Hydroxydopamine (6-OHDA) is one of...
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Comparison of the Protective Effect of Indole beta-carbolines and R-(-)-deprenyl Against Nitrogen Species-Induced Cell Death in Experimental Culture Model of Parkinson's Disease

Han YS, Kim JM, Cho JS, Lee CS, Kim DE

BACKGROUND: The membrane permeability transition of mitochondria has been suggested to be involved in toxic and oxidative forms of cell injury. Mitochondrial dysfunction is considered to play a critical role...
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Botulinum Toxin Type A for Facial Wrinkles and Benign Masseter Hypertrophy in Korean Patients

Rho NK, Kim HS, Kim YS, Kim YJ, Kim CH, Min PK, Suh SB, Lee KS, Lee SJ, Lee WS, Cho HR, Choi SW, Hwang JY, Kim HJ

  • KMID: 2247668
  • Korean J Dermatol.
  • 2010 Oct;48(10):823-831.
BACKGROUND: The utilization of botulinum toxin has rapidly expanded into various aesthetic applications. Achieving success with the aesthetic use of neurotoxins depends on several factors, including an understanding of the...
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