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Effect of levetiracetam on rocuronium duration in patients undergoing cerebrovascular surgery

Jeon YJ, Kim MH

BACKGROUND: It has long been held that antiepileptics reduce the duration of action, and increase the requirement for, neuromuscular blocking agents. However, levetiracetam, a relatively novel antiepileptic agent, possesses different...
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The Effect of Succinylcholine on the Neuromuscular Block Induced with Mivacurium in the abbits

Kwon OK, Shim JY, Kim YT

BACKGROUND: There were many reports about the effect of succinylcholine on the action of nondepolarizing muscle relaxants. The results are inconsistent depend on the nondepolarizing muscles relaxants used, time when...
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A survey of current concepts and practices related to use of neuromuscular blockers with antagonists and neuromuscular monitoring among Korean anesthesiologists

Choi S, Jung M, Kim KM, Lee S, Yang HS, Lee JS

BACKGROUND: The goal of this nationwide survey was to investigate the current concepts and practices of the use of neuromuscular blockers and their antagonists, and the availability and clinical practice...
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Nefopam does not influence onset and recovery profiles of rocuronium-induced neuromuscular block: a prospective, double-blinded, randomized, controlled study

So KY, Moon HM, Kim SH

BACKGROUND: We investigated the hypothesis that pretreatment with nefopam 20 mg would influence the onset and recovery profiles of rocuronium-induced neuromuscular block. METHODS: After Institutional Review Board approval, 134 patients, aged...
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Cardiac arrest following reversal of muscle relaxation by pyridostigmine: A case report

Jo JY, Yi JM, Lee YK, Ku SW, Park PH

  • KMID: 1908529
  • Anesth Pain Med.
  • 2014 Jul;9(3):205-208.
The anticholinesterase pyridostigmine is usually used as a reversal agent of non-depolarizing muscle relaxants in general anesthesia. Most adverse muscarinic effects of anticholinesterases are controlled by anticholinergics; however, there is...
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The Train-of-Four Ratio Profile During Onset and Offset Following Administration of Neuromuscular Blocking Agents

Kim SC, Lee JS, Yoon CS, Kim MH, Park W, Kim SY, Choi SJ

BACKGROUND: The train of four (TOF) stimulation is valuable to study pharmacodynamics associated with the interaction between muscle relaxants and receptors in the neuromuscular junction. TOF fade expresses presynaptic effect...
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Predicting Recovery from Deep Neuromuscular Block by Rocuronium During Sevoflurane versus Propofol Anesthesia

Jeong JS, Lee SH, Jeon YH, Moon C, Kim SO, Baek WY

BACKGROUND: The use of volatile anesthetics for the maintenance of anesthesia can enhance the action and prolong the duration of non-depolarizing muscle relaxants. The objective of this study was to...
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Effects of Ondansetron on the Neuromuscular Block of Vecuronium, Rocuronium or Atracurium in a Rat Phrenic Nerve-Hemidiaphragm Preparation

Ok SY, Kim SC, Kim SI, Lee JS, Jung JY, Hwang KH, Kim SY

BACKGROUND: Ondansetron, a 5-HT3 receptor antagonist, is widely used for the prevention of postoperative nausea and vomiting. However, the interaction of ondansetron with non-depolarizing muscle relaxants have not been reported...
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Streptozotocin Diabetes Attenuates the Effects of Nondepolarizing Neuromuscular Relaxants on Rat Muscles

Huang L, Chen D, Li S

The hypothesis of this study was that diabetes-induced desensitization of rat soleus (SOL) and extensor digitorum longus (EDL) to non-depolarizing muscle relaxants (NDMRs) depends on the stage of diabetes and...
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Neuromuscular and hemodynamic effects of mivacurium and succinylcholine in adult patients during nitrous oxide-propofol-fentanyl anesthesia

Hwang KH, Kim SC, Kim SY, Ueda N, Muteki T

The neuromuscular and hem+odynamic effects of mivacurium 0.15 mg/kg and succinylcholine 1 mg/kg were compared in 26 adult patients (ASA I and II) during nitrous oxide-oxygen-propofol-fentanyl anesthesia. Neuromuscular block was...
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Recovery from Rocuronium-induced Neuromuscular Blockade during Sevoflurane or Propofol Anesthesia in Pediatric Patients

Kang SY, Kim CH, Han JI, Lee GY

BACKGROUND: Potent inhalation anesthetics potentiate the neuromuscular blocking effects of non-depolarizing muscle relaxants. Therefore, sevoflurane may increase the safety margin at the end of anesthesia by reducing the muscle relaxant...
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Effect of Administration of Vecuronium or Rocuronium on Recovery from Pancuronium and Vice Versa in Isolated Forearm

Kang KS, Song JE, Lee JS, Hwang KH, Kim SY

BACKGROUND: It is important to consider the sequential administration of long- and short-acting non-depolarizing muscle relaxants. The purpose of this study is to evaluate the interaction between non-depolarizing muscle relaxants...
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The Influence of Gallamine , d-Tubocurarine and Pancuronium on Intracranial Pressure and Blood Pressure of Rabbits

Ha IH, Kim WT

  • KMID: 2357750
  • Korean J Anesthesiol.
  • 1978 Dec;11(4):324-328.
Arterial pressure increased from normal to 80~90 mrn Hg, 90~100 mm Hg & 110 ~130 mmHg when the intracrania1 pressure was mechanically elevated to 20~40, mm Hg, 50~70 mm...
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The infusion rate of mivacurium or atracurium for cesarean section compared with gynecological procedures

Kim JH, Min KT, Ahn EK, Kim KH, Shin YS

Mivacurium is mainly metabolized by plasma cholinesterase, whereas atracurium is removed by Hofman elimination. The purpose of this study was to compare the infusion rate of atracurium and...
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Effects of adenosine receptor agonist on the rocuronium-induced neuromuscular block and sugammadex-induced recovery

Kim YB, Lee S, Choi HR, In J, Chang YJ, Kim HJ, Ro YJ, Yang HS

BACKGROUND: Several types of receptors are found at neuromuscular presynaptic membranes. Presynaptic inhibitory A1 and facilitatory A2A receptors mediate different modulatory functions on acetylcholine release. This study investigated whether adenosine...
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Succinylcholine-Induced Fasciculation is Prevented by Mivacurium-Precurarization

Chung KH, Kang JW, Lee JY

  • KMID: 2228733
  • Korean J Crit Care Med.
  • 1999 Jun;14(1):31-36.
BACKGOUND: Succinylcholine (SCC) injection may be associated with adverse effects including elevated serum potassium (K ) and creatinine phosphokinase (CPK) level, and postoperative myalgia. Many studies have been made to...
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The Influence of Succinylcholine and Tracheal Tube Lubrication on Postoperative Sore Throat

Lim CH, Kim JH, Jeon EH, Lim HJ, Chae BK, Kim NS, Chang SH

BACKGROUND: Sore throat has been reported to occur in 24-90% of intubated patients after general anesthesia. This study was done to evaluate the influence of succinycholine and tracheal tube lubrication...
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A Changes in Blood Pressure with Varying Rates of Adminstration of d-Tubocurarine

Kim HS, Kim W, Shin OY, Kwon MI

  • KMID: 2237196
  • Korean J Anesthesiol.
  • 1981 Sep;14(3):264-270.
d-tubocurarine is one of the non-depolarizing muscle relaxants which is most commonly used in clinical situations d-Tc is used as a selective muscle relaxant in hypertensive patients or patients for...
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Comparison of Train-of-four Response between Adductor Pollicis and Orbicularis Oculi to Determine the Optimal Time for Endotracheal Intubation after Vecuronium Administration

Lee HS, Chung CK, Cha YD, Park DH, Song CH, Lee SK

BACKGROUND: Ideal condition of endotracheal intubation after administration of non-depolarizing muscle relaxants like vecuronium is the time when the diaphragm and upper airway muscles are completely relaxed. But these muscles...
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Influence of Midazolam on Serum Potassium and Creatine Phosphokinase Levels

Kim JY, Suh JK, Kim YJ, Shim JC, Hwang YH, Yoo HK, Park DH, Suh BT, Kim WS

  • KMID: 1932837
  • Korean J Anesthesiol.
  • 1983 Sep;16(3):221-228.
Succinylcholine is used most widely for tracheal intubation during induction for general anesthesia. However adverse effects following the administration of succinylcholine which include an increase of serum potassium, creatine...
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