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Role of a 19S Proteasome Subunit- PSMD10(Gankyrin) in Neurogenesis of Human Neural Progenitor Cells

Sahu I, Nanaware P, Mane M, Mulla SW, Roy S, Venkatraman P

PSMD10(Gankyrin), a proteasome assembly chaperone, is a widely known oncoprotein which aspects many hall mark properties of cancer. However, except proteasome assembly chaperon function its role in normal cell function...
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Neurogenesis and Regulation of Olfactory Epithelium

Kim JS, Kim BG

The olfactory epithelium is capable of structural and functional recovery after injury through neurogenesis. Neurogenesis occurs via stem cells in the olfactory epithelium. Horizontal basal cells and globose basal cells...
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Neurogenesis and neuronal migration of dopaminergic neurons during mesencephalon development in mice

Kim MK, Lee SJ, Vasudevan , Won C

Dopaminergic neurons are one of the major neuronal components in the brain. Mesencephalon dopamine (DA) neurogenesis takes place in the ventricular zone of the floor plate, when DA progenitors divide...
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Toll-like receptor 2 promotes neurogenesis from the dentate gyrus after photothrombotic cerebral ischemia in mice

Seong KJ, Kim HJ, Cai B, Kook MS, Jung JY, Kim WJ

The subgranular zone (SGZ) of hippocampal dentate gyrus (HDG) is a primary site of adult neurogenesis. Toll-like receptors (TLRs), are involved in neural system development of Drosophila and innate immune...
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Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function

Han MH, Lee EH, Koh SH

Neurological diseases such as Alzheimer, Parkinson, and ischemic stroke have increased in occurrence and become important health issues throughout the world. There is currently no effective therapeutic strategy for addressing...
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Neurourological Application of Neurogenesis and Inflammation and Pain Mechanisms of Rocuronium Bromide

Kim KH

No abstract available.
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Adult Neurogenesis and Gliogenesis: Possible Mechanisms for Neurorestoration

Rusznák Z, Henskens W, Schofield , Kim WS, Fu Y

The subgranular zone (SGZ) and subventricular zone (SVZ) are developmental remnants of the germinal regions of the brain, hence they retain the ability to generate neuronal progenitor cells in adult...
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Epigallocatechin-3-gallate rescues LPS-impaired adult hippocampal neurogenesis through suppressing the TLR4-NF-kappaB signaling pathway in mice

Seong KJ, Lee HG, Kook MS, Ko HM, Jung JY, Kim WJ

Adult hippocampal dentate granule neurons are generated from neural stem cells (NSCs) in the mammalian brain, and the fate specification of adult NSCs is precisely controlled by the local niches...
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Centella asiatica enhances neurogenesis and protects neuronal cells against H2O2-induced oxidative injury

Kim H, Hong JT, Park MH

Traditionally, Centella asiatica leaf extracts are used to treat neurodegenerative diseases in India. Centella asiatica is reportedly used to enhance memory and treat dementia, but its promoting effect on neural...
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An Aminopropyl Carbazole Derivative Induces Neurogenesis by Increasing Final Cell Division in Neural Stem Cells

Shin JY, Kong SY, Yoon HJ, Ann J, Lee J, Kim HJ

P7C3 and its derivatives, 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(p-tolylamino)propan-2-ol (1) and N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-hydroxypropyl)-N-(3-methoxyphenyl)-4-methylbenzenesulfonamide (2), were previously reported to increase neurogenesis in rat neural stem cells (NSCs). Although P7C3 is known to increase neurogenesis by protecting...
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The 5-hydroxytryptamine 4 Receptor Agonist-induced Actions and Enteric Neurogenesis in the Gut

Takaki M, Goto K, Kawahara I

  • KMID: 2381146
  • J Neurogastroenterol Motil.
  • 2014 Jan;20(1):17-30.
We explored a novel effect of 5-hydroxytryptamine 4 receptor (5-HT4R) agonists in vivo to reconstruct the enteric neural circuitry that mediates a fundamental distal gut reflex. The neural circuit insult...
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New Perspectives of Dyrk1A Role in Neurogenesis and Neuropathologic Features of Down Syndrome

Park J, Chung KC

Down syndrome (DS) is one of the most common genetic disorders accompanying with mental retardation, cognitive impairment, and deficits in learning and memory. The brains with DS also display many...
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Increase of Angiogenesis and Neurogenesis, and Neurobehavioral Recovery by Transplanted Mesenchymal Stem Cells in the Ischemic Rat Brain

Lee WS, Huh PW

  • KMID: 2089923
  • Korean J Cerebrovasc Surg.
  • 2007 Dec;9(4):277-285.
OBJECT: In this study, murine mesechymal stem cells (MSC) was grafted to cerebral ischemia rats, the differentiation of the transplanted MSC was assessed, and at that time, the association of...
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Effects of electromagnetic stimulation on neurogenesis and neuronal proliferation in rat hippocampal slice culture

Kim DS, Choi ES, Chae SA

PURPOSE: Transcranial electromagnetic stimulation(TMS) is a noninvasive method which stimulates the central nervous system through pulsed magnetic fields without direct effect on the neurons. Although the neurobiologic mechanisms of magnetic...
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Hippocampal Neurogenesis and Its Phenotypic Differentiation after Kainic Acid-induced Seizures in Mice

Choi ES, Jeong SW, Jang HO, Hong KS, Kim DW

  • KMID: 2185339
  • J Korean Neurol Assoc.
  • 2005 Aug;23(4):503-509.
BACKGROUND: Proliferation and survival of dentate granule cells are influenced by epileptic seizures. Dentate granule cells might play an important role in the pathogenesis of temporal lobe epilepsy. However, most...
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Endogenous Neurogenesis in Postnatal Brain

Chang YS

  • KMID: 1629573
  • Korean J Pediatr.
  • 2005 Aug;48(8):806-812.
Repair mechanisms in the postnatal and mature central nervous system (CNS) have long been thought to be very limited. However recent works have shown that the mature CSN contains neural...
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Neurogenesis and Epilepsy

Jeong SW, Kim DW

  • KMID: 1640563
  • J Korean Epilepsy Soc.
  • 2004 Dec;8(2):97-102.
Data accumulated over the past four decades have dispelled the long-held dogma that the adult mammalian brain cannot generate new neurons. Although neurogenesis, the birth of new neurons, is confined...
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The Effect of Transient Global Ischemia on the Rat Dentate Gyrus: Apoptosis in the Granular Zone and Neurogenesis in the Subgranular Zone

Jung Y, Hong S

  • KMID: 2092843
  • Korean J Anat.
  • 2004 Oct;37(5):467-479.
It has been known that granule neurons of the dentate gyrus (DG) are born in adulthood as well as during development. Apoptotic cell death also occurs normally throughout the life...
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Neurogenesis and Psychiatry: Focusing on Mood Disorders

Lee JS, Yang BH

  • KMID: 2340755
  • J Korean Neuropsychiatr Assoc.
  • 2002 Sep;41(5):796-804.
Up to now, the adult brain has been considered largely refractory to regeneration and new neuronal birth(neurogenesis). However, recent studies have clearly revealed that the adult hippocampus, specifically the dentate...
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