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Stress, Inflammation and Neurogenesis in Major Depression

Kim YK

  • KMID: 2299888
  • Korean J Biol Psychiatry.
  • 2011 Nov;18(4):169-175.
Stress, a risk factor of major depression induces cytokine mediated inflammation and decreased neurogenesis. In patients with major depression, significant increases of pro-inflammatory cytokines have been consistently reported. The pro-inflammatory...
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Adult Neurological Handicap: New Insight from Neurogenesis

Kim KH

  • KMID: 2232827
  • Int Neurourol J.
  • 2012 Jun;16(2):55-56.
No abstract available.
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Neurogenesis and Regulation of Olfactory Epithelium

Kim JS, Kim BG

The olfactory epithelium is capable of structural and functional recovery after injury through neurogenesis. Neurogenesis occurs via stem cells in the olfactory epithelium. Horizontal basal cells and globose basal cells...
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Neurourological Application of Neurogenesis and Inflammation and Pain Mechanisms of Rocuronium Bromide

Kim KH

No abstract available.
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Adult Neurogenesis in the Central and Peripheral Nervous Systems

Kim HJ, Sun W

  • KMID: 2232828
  • Int Neurourol J.
  • 2012 Jun;16(2):57-61.
Neurogenesis occurs during embryonic development and continues throughout adulthood. Although spontaneous adult neurogenesis is restricted to selective germinal regions, including the subventricular zone and dentate gyrus of the hippocampus, neural...
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Adult Neurogenesis and Gliogenesis: Possible Mechanisms for Neurorestoration

Rusznák Z, Henskens W, Schofield , Kim WS, Fu Y

The subgranular zone (SGZ) and subventricular zone (SVZ) are developmental remnants of the germinal regions of the brain, hence they retain the ability to generate neuronal progenitor cells in adult...
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Neurogenesis and Epilepsy

Jeong SW, Kim DW

  • KMID: 1640563
  • J Korean Epilepsy Soc.
  • 2004 Dec;8(2):97-102.
Data accumulated over the past four decades have dispelled the long-held dogma that the adult mammalian brain cannot generate new neurons. Although neurogenesis, the birth of new neurons, is confined...
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Neurogenesis and Psychiatry: Focusing on Mood Disorders

Lee JS, Yang BH

  • KMID: 2340755
  • J Korean Neuropsychiatr Assoc.
  • 2002 Sep;41(5):796-804.
Up to now, the adult brain has been considered largely refractory to regeneration and new neuronal birth(neurogenesis). However, recent studies have clearly revealed that the adult hippocampus, specifically the dentate...
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Neuroprotection in Schizophrenia and Its Therapeutic Implications

Kim YK, Na KS

Schizophrenia is a chronic and debilitating mental disorder. The persisting negative and cognitive symptoms that are unresponsive to pharmacotherapy reveal the impairment of neuroprotective aspects of schizophrenia. In this review,...
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Neural Stem Cells and Ischemic Brain

Zhang Z, Chopp M

Stroke activates neural stem cells in the ventricular-subventricular zone (V/SVZ) of the lateral ventricle, which increases neuroblasts and oligodendrocyte progenitor cells (OPCs). Within the ischemic brain, neural stem cells, neuroblasts...
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Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function

Han MH, Lee EH, Koh SH

Neurological diseases such as Alzheimer, Parkinson, and ischemic stroke have increased in occurrence and become important health issues throughout the world. There is currently no effective therapeutic strategy for addressing...
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Neurogenesis and neuronal migration of dopaminergic neurons during mesencephalon development in mice

Kim MK, Lee SJ, Vasudevan , Won C

Dopaminergic neurons are one of the major neuronal components in the brain. Mesencephalon dopamine (DA) neurogenesis takes place in the ventricular zone of the floor plate, when DA progenitors divide...
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Biological Studies on Alcohol-Induced Neuronal Damage

Tateno M, Saito T

  • KMID: 2315781
  • Psychiatry Investig.
  • 2008 Mar;5(1):21-27.
Alcohol is a well-known cytotoxic agent which causes various kinds of neuronal damage. In spite of thousands of published studies, the true mechanism of alcohol-induced neuronal damage remains unclear. Neurogenesis...
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An Aminopropyl Carbazole Derivative Induces Neurogenesis by Increasing Final Cell Division in Neural Stem Cells

Shin JY, Kong SY, Yoon HJ, Ann J, Lee J, Kim HJ

P7C3 and its derivatives, 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(p-tolylamino)propan-2-ol (1) and N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-hydroxypropyl)-N-(3-methoxyphenyl)-4-methylbenzenesulfonamide (2), were previously reported to increase neurogenesis in rat neural stem cells (NSCs). Although P7C3 is known to increase neurogenesis by protecting...
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Effects of Indomethacin on Ischemia-induced Brain Injury

Jung DY, Baek SY, Cho MK, Han ME, Kim BS, Kim JB, Oh SO

  • KMID: 2224457
  • Korean J Anat.
  • 2007 Sep;40(3):179-191.
Cerebral ischemia can have severe results and disrupt quality of life. Current medicine is not effective at overcoming these problems. To find out more effective therapies, it is necessary to...
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Isolation of Early Neurogenesis Genes with Xenopus cDNA Microarray

Yu SB, Lee OJ, Park YJ, Lee SY, Lee SH, Yoon J, Hwang YS, Kim JI, Lee JY, Park JB, Kim SC, Kim J

Neurogenesis is the process that develops neuroectoderm from ectoderm. Bone morphogenetic protein (BMP) inhibition in ectodermal cells is necessary and sufficient for neurogenesis in Xenopus embryos. To isolate genes involved...
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Effects of 6-hydroxydopamine on the Adult Neurogenesis of Dopaminergic Neurons in the Mouse Midbrain

Kim TW, Kim H, Sun W

Recently, restricted progenitor cells have been identified in the substantia nigra (SN) of the rat and mouse, raising a hope that resident stem/progenitor cells may be useful for the therapy...
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Odor Enrichment Increases Hippocampal Neuron Numbers in Mouse

Rusznák Z, Sengul G, Paxinos G, Kim WS, Fu Y

The hippocampus and olfactory bulb incorporate new neurons migrating from neurogenic regions in the brain. Hippocampal atrophy is evident in numerous neurodegenerative disorders, and altered hippocampal neurogenesis is an early...
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Repeated restraint stress promotes hippocampal neuronal cell ciliogenesis and proliferation in mice

Lee K, Ko HW

Stress severely disturbs physiological and mental homeostasis which includes adult neurogenesis in hippocampus. Neurogenesis in hippocampus is a key feature to adapt to environmental changes and highly regulated by multiple...
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Endogenous Neurogenesis in Postnatal Brain

Chang YS

  • KMID: 1629573
  • Korean J Pediatr.
  • 2005 Aug;48(8):806-812.
Repair mechanisms in the postnatal and mature central nervous system (CNS) have long been thought to be very limited. However recent works have shown that the mature CSN contains neural...
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