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The Morphological Studies on the Effects of Nerve Growth Factor on the Schwann Cell in the Diabetic Neuropathy in the Rats

Ahn SK, Lee JE, Lee WT, Park SH, Park KA

  • KMID: 2224534
  • Korean J Anat.
  • 2000 Dec;33(6):723-731.
Diabetic neuropathy is a broad term that encompasses many destructive syndromes that various kinds of neuronal population is affected in diabetes mellitus. Diabetic neuropathy has been postulated to occur by...
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Expression of Neurotrophic Factors and Their Receptors mRNAs in the Rat Dorsal Root Ganglion Following Peripheral Nerve Injury

Baek SY, Yang MS, Moon YS, Kim BS, Kim JB, Kim JJ

  • KMID: 2224583
  • Korean J Anat.
  • 1999 Apr;32(2):221-229.
Degenerative and regnerative changes are occurred in the dorsal root ganglion (DRG) cells after the peripheral nerve injury. This experiment aimed to study the changes of neurotrophic factors and their...
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A Correlation between Peripheral and Penile Serum Levels of Nerve Growth Factor in Healthy potent Controls

Cho JS, Lee SK, Kim JW, Lee HS, Park HW

  • KMID: 2327934
  • J Korean Androl Soc.
  • 1996 Dec;14(2):87-90.
Nerve growth factor (NGF) is a potent neurotrophin signaling protein, the best-known member of a family of similar neurotrophins. Specific neuronal populations depends upon the neurotrophins for normal function...
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Sciatic nerve leachate of cattle causes neuronal differentiation of PC12 cells via ERK1/2 signaling pathway

Zhang Z, Liu Y, Zhu X, Wei L, Zhu J, Shi K, Wang G, Pan L

Previous studies have shown that the sciatic nerve has neurotrophic activity, and nerve regeneration, differentiation, and axon outgrowth can be modulated by different sciatic nerve preparations. However, numerous animals may...
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Effect of Midkine (MK) on Cultured Spinal Motor Neurons Damaged by Oxidative Stress

Park ST, Chung YT

To evaluate the effect of midkine (MK), neurotrophic factor on cultured mouse spinal motor neuron, NSC-19 which was inhibited by glucose oxidase (GO)-induced oxygen radicals, MTT assay and neurofilament enzymeimmunoassay...
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Rat Peripheral Nerve Regeneration Using Nerve Guidance Channel by Porcine Small Intestinal Submucosa

Yi JS, Lee HJ, Lee HJ, Lee IW, Yang JH

OBJECTIVE: In order to develop a novel nerve guidance channel using porcine small intestinal submucosa (SIS) for nerve regeneration, we investigated the possibility of SIS, a tissue consisting of acellular...
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Effect of Platelet Rich Plasma on Facial Nerve Regeneration in Acute Nerve Injury Model

Cho HH, Lee SC, Jang SJ, Kim SH, Jeong HS, Park JS, Han JY, Lee KH, Cho YB

BACKGROUND AND OBJECTIVES: The object of this study was to evaluate the effect of platelet rich plasma (PRP) on facial nerve regeneration from an axotomy injury in the guinea pig...
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Tyrosine Protein Kinase (trk) Receptors Expression in Malignant Melanoma Cells

Lee JY, Park YL, Whang KU

  • KMID: 2425606
  • Korean J Dermatol.
  • 1997 Dec;35(6):1151-1158.
BACKGROUND: Nerve growth factor(NGF), brain derived neurotrophic factor(BDNF), neurotropin 3(NT-3) and neurotropir-4/5 are neurotrophic factors necessary for the development and maintenance of specific neurors. The tyrosine protein kinase(trk) receptors exhibit...
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Effect of Nerve Growth Factor on Cultured Rat Schwann Cells in Hyperglycemic Condition

Hyung GY, Kim KH, Baek SH, Jang GY, Cho CG

  • KMID: 1539926
  • J Korean Diabetes Assoc.
  • 2000 Feb;24(1):10-18.
BACKGROUND: Nerve growth factor (NGF) is produced in tissues innervafed by its responsive neurons. In the peripheral nervous system, NGF messenger RNA (mRNA) is produced in target fields of small...
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Expression of the mRNA of Growth Factor Receptors and Neurotrophic Factors in Porcine Vesical Submucosa and Acellular Matrix

Moon HC, Joo KJ, Park HJ

  • KMID: 2293814
  • Korean J Urol.
  • 2005 Dec;46(12):1344-1347.
PURPOSE: Several naturally-derived biopolymers have been introduced as implantable biomaterial for tissue reconstruction, and some of them are already being applied in various clinical fields. They serve as backbones for...
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The effect of 4-Methylcatechol treatment in chronic constrictive injury of the rat sciatic nerve on the allodynia and spinal neurotrophic factors

Choi SH, Shin SW, Kim HJ, Kim WS

BACKGROUND: The effect of chronic administration of 4-methylcatechol known as a neurotrophic factor inducer on the allodynia and spinal neurotrophic factors was investigated in chronic constrictive injury of sciatic nerve...
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Mitogen Activated Protein Kinase Family Proteins and c-jun Signaling in Injury-induced Schwann Cell Plasticity

Lee HJ, Shin YK, Park HT

Schwann cells (SCs) in the peripheral nerves myelinate axons during postnatal development to allow saltatory conduction of nerve impulses. Well-organized structures of myelin sheathes are maintained throughout life unless nerves...
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Roles of Matrix Metalloproteinases and Their Targets in Epileptogenesis and Seizures

Mizoguchi , Yamada K

  • KMID: 2171153
  • Clin Psychopharmacol Neurosci.
  • 2013 Aug;11(2):45-52.
Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) remodel the pericellular environment by regulating the cleavage of extracellular matrix proteins, cell surface components, neurotransmitter receptors, and growth factors, which...
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Arrhythmogenic Gene Change and Nerve Sprouting after Acute Myocardial Infarction in Mice

Oh YS, Kim JH, Choi YS, Park HW, Lee DH, Shin WS, Youn HJ, Lee MY, Chung WS, Rho TH, Kim JH, Chen PS, Choi KB

BACKGROUND AND OBJECTIVES: Myocardial infarction (MI) elicits nerve sprouting. However, the time course and spatial distribution of this nerve sprouting and its relationship to the expression of neurotrophic factors is...
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Neurotoxic Effect of Streptozotocin and Neuroprotective Effect of Insulin Growth Factor-II to the Cultured Mouse Schwann Cells

Jang CH, Park ST

  • KMID: 2012698
  • Korean J Otolaryngol-Head Neck Surg.
  • 2000 Jun;43(6):577-581.
BACKGROUND: The sensorineural hearing loss due to diabetes is progressive and bilateral, and predominantly occurs in the old, although its accurate pathogenesis is still unknown. Objectives: The purpose of this...
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Valproic Acid Effect in Nerve Regeneration Using Gore-Tex(R) Tube Filled with Skeletal Muscle

Kang NH, Oh HB, Lee KH, Kim JG

  • KMID: 2203385
  • J Korean Soc Plast Reconstr Surg.
  • 2006 Mar;33(2):213-218.
As the large defect of peripheral nerve occurs, the autologous nerve graft is the most ideal method but it has many limitations due to donor site morbidities. Various materials have...
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Clinical Application of Fat Tissue Wraparound Splint after Facial Nerve Repair

Lee YJ, Ha WH

Facial deformity after nerve injury changes ones' social life. We experienced a few patients with healthy early recovery of muscle contraction after the operation with soft tissue wraparound splint. Under...
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Neural Ablation and Regeneration in Pain Practice

Choi EJ, Choi YM, Jang EJ, Kim JY, Kim TK, Kim KH

A nerve block is an effective tool for diagnostic and therapeutic methods. If a diagnostic nerve block is successful for pain relief and the subsequent therapeutic nerve block is effective...
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Xenotransplant of human bone marrow stromal cells: effect on the regeneration of axotomized infraorbital nerve in rats

Park EJ, Kim ES, Kim JM, Kim HO, Yum KW

  • KMID: 2190394
  • J Korean Assoc Oral Maxillofac Surg.
  • 2005 Jun;31(3):239-247.
This study demonstrated that xenogenic human marrow mesenchymal stem cells (hMSCs) could elicit the regeneration of the sensory nerve after axotomy in the adult rats'infraorbital nerves without immunosuppression. For this,...
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Immunohistochemical Study of TrkA Neurotrophin Receptor Expression during Thymic Regeneration

Kim SH, Jun EJ, Baek SY, Sung SC, Yoon S

  • KMID: 2224562
  • Korean J Anat.
  • 2000 Jun;33(3):263-270.
Numerous studies have demonstrated interactions between the nervous/endocrine and the immune system. Increasing evidence suggests that some members of neurotrophins such as nerve growth factor (NGF) are involved in the...
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