- Naltrexone-associated Visual Hallucinations: A Case Report
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Lee DB, Woo YS, Bahk WM
- KMID: 2456739
- Clin Psychopharmacol Neurosci.
- 2019 Mar;17(2):329-331.
- doi: 10.9758/cpn.2019.17.2.329
Naltrexone is a competitive antagonist of μ, δ, and κ opioid receptors. Naltrexone has been investigated for use an as anti-obesity agent in both the general population and in patients... -
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- Opioid-induced constipation: a narrative review of therapeutic options in clinical management
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Lang-Illievich K, Bornemann-Cimenti H
- KMID: 2449819
- Korean J Pain.
- 2019 Apr;32(2):69-78.
- doi: 10.3344/kjp.2019.32.2.69
Pain therapy often entails gastrointestinal adverse events. While opioids are effective drugs for pain relief, the incidence of opioid-induced constipation (OIC) varies greatly from 15% to as high as 81%.... -
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- Spinal Gabapentin and Antinociception: Mechanisms of Action
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Yoon MH, Choi JI, Jeong SW
- KMID: 2157631
- J Korean Med Sci.
- 2003 Apr;18(2):255-261.
- doi: 10.3346/jkms.2003.18.2.255
Spinal gabapentin has been known to show the antinociceptive effect. Although several assumptions have been suggested, mechanisms of action of gabapentin have not been clearly established. The present study was... -
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- Cardiopulmonary Effect of Doxapram after Balanced Anesthesia with Pethidine-Diazepam-Nitrous Oxide
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Kim CH
- KMID: 1965118
- Ewha Med J.
- 1992 Jun;15(2):149-155.
- doi: 10.12771/emj.1992.15.2.149
Doxapram is a central and peripheral respiratory stimulant that has been primarily used to counteract postanesthetic respiratory depression. Administration of opioid in doses sufficient to produce anesthesia is invariably associated with... -
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- Treatment of Constipation
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Park MI
- KMID: 2258948
- Korean J Med.
- 2011 May;80(5):510-523.
Constipation is a common gastrointestinal disease affecting approximately 16.5% of the population in Korea. Systemic diseases such as hypothyroidism or colon cancer and drugs can cause constipation in some patients... -
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- Functional activity of the cannabinoid 1 receptor is not affected by opioid antagonists in the rat brain
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Lee H
- KMID: 1767337
- Korean J Anesthesiol.
- 2013 Mar;64(3):257-261.
- doi: 10.4097/kjae.2013.64.3.257
BACKGROUND: WIN55212-2 is a synthetic cannabinoid agonist and selective to cannabinoid 1 (CB1) receptors, which are distributed mainly in the central nervous system. Opioid receptors and CB1 receptors have several... -
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- Differential expression of spinal γ-aminobutyric acid and opioid receptors modulates the analgesic effects of intrathecal curcumin on postoperative/inflammatory pain in rats
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Ju J, Shin JY, Yoon JJ, Yin M, Yoon MH
- KMID: 2436061
- Anesth Pain Med.
- 2018 Jan;13(1):82-92.
- doi: 10.17085/apm.2018.13.1.82
BACKGROUND: Curcumin is traditionally used as an herbal medicine. We explored the efficacy of intrathecal curcumin in relieving both postoperative and inflammatory pain and elucidated the mechanisms of action of... -
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- Effects of Co-Administration of Intrathecal Nociceptin/Orphanin FQ and Opioid Antagonists on Formalin-Induced Pain in Rats
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Lee H
- KMID: 1727895
- Yonsei Med J.
- 2013 May;54(3):763-771.
- doi: 10.3349/ymj.2013.54.3.763
PURPOSE: Nociceptin/orphanin FQ (N/OFQ) as an endogeneous hexadecapeptide is known to exert antinociceptive effects spinally. The aims of this study were to demonstrate the antinociceptive effects of i.t. N/OFQ and... -
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- Effects of Naloxegol on Gastrointestinal Transit and Colonic Fecal Volume in Healthy Participants Receiving Oxycodone
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Olesen AE, Grønlund , Mark EB, Krogh K, Frøkjær , Drewes AM
- KMID: 2460489
- J Neurogastroenterol Motil.
- 2019 Oct;25(4):602-610.
- doi: 10.5056/jnm18079
BACKGROUND/AIMS: Opioids cause gastrointestinal (GI) dysmotility, decrease gut secretion, and affect gut sphincters. Symptoms of opioid-induced bowel dysfunction may be alleviated by peripherally acting opioid antagonists like naloxegol, but detailed... -
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- Analgesic effects of eucalyptus essential oil in mice
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Lee G, Park J, Kim MS, Seol GH, Min SS
- KMID: 2449820
- Korean J Pain.
- 2019 Apr;32(2):79-86.
- doi: 10.3344/kjp.2019.32.2.79
BACKGROUND: The use of aroma oils dates back to at least 3000 B.C., where it was applied to mummify corpses and treat the wounds of soldiers. Since the 1920s, the... -
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- Difference of the Naltrexone's Effects in Social Drinkers by Spicy Food Preference
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Lee JS, Kim SG, Jeong HJ, Kim JH, Yang YH, Jung WY
- KMID: 1786115
- J Korean Med Sci.
- 2014 May;29(5):714-718.
- doi: 10.3346/jkms.2014.29.5.714
The purpose of this study was to investigate the differences in subjective acute effects of alcohol and naltrexone among those who prefer spicy food to varying degrees. Acute biphasic alcohol... -
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- Colorectal Transit and Volume During Treatment With Prolonged-release Oxycodone/Naloxone Versus Oxycodone Plus Macrogol 3350
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Poulsen JL, Mark EB, Brock C, Frøkjær , Krogh K, Drewes AM
- KMID: 2417279
- J Neurogastroenterol Motil.
- 2018 Jan;24(1):119-127.
- doi: 10.5056/jnm17058
BACKGROUND/AIMS: Opioid-induced constipation (OIC) is the most common gastrointestinal (GI) side effect to opioid treatment. Opioid receptor antagonists against OIC have been introduced, but their efficacy has not been directly... -
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- Morphine Postconditioning Attenuates ICAM-1 Expression on Endothelial Cells
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Min TJ, Kim JI, Kim JH, Noh KH, Kim TW, Kim WY, Lee YS, Park YC
- KMID: 1782121
- J Korean Med Sci.
- 2011 Feb;26(2):290-296.
- doi: 10.3346/jkms.2011.26.2.290
The purpose of this study is to determine 1) whether morphine postconditiong (MPostC) can attenuate the intercellular adhesion molecules-1 (ICAM-1) expression after reoxygenation injury and 2) the subtype(s) of the... -
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- Additive Antinociception between Intrathecal Sildenafil and Morphine in the Rat Formalin Test
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Yoon MH, Park KD, Lee HG, Kim WM, An TH, Kim YO, Huang LJ, Hua CJ
- KMID: 1107530
- J Korean Med Sci.
- 2008 Dec;23(6):1033-1038.
- doi: 10.3346/jkms.2008.23.6.1033
The possible characteristics of spinal interaction between sildenafil (phosphodiesterase 5 inhibitor) and morphine on formalin-induced nociception in rats was examined. Then the role of the opioid receptor in the effect... -
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