- Mitochondrial dysfunction reduces the activity of KIR2.1 K⺠channel in myoblasts via impaired oxidative phosphorylation
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Woo J, Kim HJ, Nam YR, Kim YK, Lee EJ, Choi I, Kim SJ, Lee W, Nam JH
- KMID: 2430092
- Korean J Physiol Pharmacol.
- 2018 Nov;22(6):697-703.
- doi: 10.4196/kjpp.2018.22.6.697
Myoblast fusion depends on mitochondrial integrity and intracellular Ca²⺠signaling regulated by various ion channels. In this study, we investigated the ionic currents associated with [Ca²âº]i regulation in normal and... -
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- Gardenia jasminoides extract and its constituent, genipin, inhibit activation of CD3/CD28 co-stimulated CD4+ T cells via ORAI1 channel
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Kim HJ, Nam YR, Woo J, Kim WK, Nam JH
- KMID: 2503329
- Korean J Physiol Pharmacol.
- 2020 Jul;24(4):363-372.
- doi: 10.4196/kjpp.2020.24.4.363
Gardenia jasminoides (GJ) is a widely used herbal medicine with antiinflammatory properties, but its effects on the ORAI1 channel, which is important in generating intracellular calcium signaling for T cell... -
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- Luteolin reduces fluid hypersecretion by inhibiting TMEM16A in interleukin-4 treated Calu-3 airway epithelial cells
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Kim HJ, Woo J, Nam YR, Seo Y, Namkung W, Nam JH, Kim WK
- KMID: 2503326
- Korean J Physiol Pharmacol.
- 2020 Jul;24(4):329-338.
- doi: 10.4196/kjpp.2020.24.4.329
Rhinorrhea in allergic rhinitis (AR) is characterized by the secretion of electrolytes in the nasal discharge. The secretion of Cl– and HCO3 – is mainly regulated by cystic fibrosis transmembrane... -
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- Anti-obesity and LDL-cholesterol lowering effects of silkworm hemolymph in C57BL/6N mice fed high fat diet
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Nam YR, Ko YE, Ly SY
- KMID: 2415216
- J Nutr Health.
- 2018 Jun;51(3):201-207.
- doi: 10.4163/jnh.2018.51.3.201
PURPOSE: Obesity, a worldwide epidemic, is associated with insulin resistance, hyperlipidemia, hypertension, cardiovascular disease, and certain cancers. Many strategies, including natural alternative anti-obesity agents, are used widely to prevent obesity.... -
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- Antioxidant activity of ethanol extract of Lycium barbarum's leaf with removal of chlorophyll
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Kim JE, Bae SM, Nam YR, Bae EY, Ly SY
- KMID: 2466680
- J Nutr Health.
- 2019 Feb;52(1):26-35.
- doi: 10.4163/jnh.2019.52.1.26
PURPOSE: The aim of this study was to estimate the antioxidant activities of 50%, 70%, and 100% ethanol extracts of Lycium barbarum leaf and chlorophyll removal extract. METHODS: The antioxidant activities... -
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- Inhibitory effects of Doenjang, Korean traditional fermented soybean paste, on oxidative stress and inflammation in adipose tissue of mice fed a high-fat diet
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Nam YR, Won SB, Chung YS, Kwak CS, Kwon YH
- KMID: 2313835
- Nutr Res Pract.
- 2015 Jun;9(3):235-241.
- doi: 10.4162/nrp.2015.9.3.235
BACKGROUND/OBJECTIVES: Doenjang, Korean traditional fermented soybean paste has been reported to have an anti-obesity effect. Because adipose tissue is considered a major source of inflammatory signals, we investigated the protective... -
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