- Diphenyleneiodonium Inhibits Apoptotic Cell Death of Gastric Epithelial Cells Infected with Helicobacter pylori in a Korean Isolate
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Cho SO, Lim JW, Kim H
- KMID: 2366360
- Yonsei Med J.
- 2015 Jul;56(4):1150-1154.
- doi: 10.3349/ymj.2015.56.4.1150
NADPH oxidase produces a large amount of reactive oxygen species (ROS) in Helicobacter pylori (H. pylori)-induced gastric epithelial cells. Even though ROS mediate apoptotic cell death, direct involvement of NADPH... -
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- Calyculin A modulates activation of the NADPH-oxidase in Me2SO-differentiated HL-60 cells
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Park JI, Uhlinger D, Chung BS, Kim IH, Kwak JY
- KMID: 755011
- Exp Mol Med.
- 1998 Dec;30(4):214-220.
Human promyelocytic leukemia cells (HL-60) have been used as a model system in which to study the effects of protein phosphatase inhibitors on NADPH-oxidase activation. Since O2- is generated by... -
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- Phagocytosis induces superoxide formation and apoptosis in macrophages
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Park JB
- KMID: 1093604
- Exp Mol Med.
- 2003 Oct;35(5):325-335.
Phagocytosis by inflammatory cells is an essential step and a part of innate immunity for protection against foreign pathogens, microorganism or dead cells. Phagocytosis, endocytotic events sequel to binding particle... -
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- Activation of nicotinic acetylcholine receptor prevents the production of reactive oxygen species in fibrillar beta amyloid peptide (1-42)-stimulated microglia
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Moon JH, Kim SY, Lee HG, Kim SU, Lee YB
- KMID: 1103583
- Exp Mol Med.
- 2008 Feb;40(1):11-18.
- doi: 10.3858/emm.2008.40.1.11
Recent studies have reported that the "cholinergic anti-inflammatory pathway" regulates peripheral inflammatory responses via alpha7 nicotinic acetylcholine receptors (alpha7 nAChRs) and that acetylcholine and nicotine regulate the expression of proinflammatory... -
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- Effect of Bilirubin on Triglyceride Synthesis in Streptozotocin-Induced Diabetic Nephropathy
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Xu J, Lee ES, Baek SH, Ahn SY, Kim S, Na KY, Chae DW, Chin HJ
- KMID: 2069807
- J Korean Med Sci.
- 2014 Sep;29(Suppl 2):S155-S163.
- doi: 10.3346/jkms.2014.29.S2.S155
We aimed to elucidate the effect of bilirubin on dyslipidemia and nephropathy in a diabetes mellitus (DM) type I animal model. Sprague-Dawley rats were separated into control, DM, and bilirubin-treated... -
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- Sodium tanshinone IIA sulfonate attenuates angiotensin II-induced collagen type I expression in cardiac fibroblasts in vitro
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Yang L, Zou XJ, Gao X, Chen H, Luo JL, Wang ZH, Liang QS, Yang GT
- KMID: 1058025
- Exp Mol Med.
- 2009 Jul;41(7):508-516.
- doi: 10.3858/emm.2009.41.7.056
Cardiac fibrosis occurs after pathological stimuli to the cardiovascular system. One of the most important factors that contribute to cardiac fibrosis is angiotensin II (Ang II). Accumulating studies have suggested... -
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- Involvement of betaPIX in angiotensin II-induced migration of vascular smooth muscle cells
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Shin EY, Lee CS, Park MH, Kim DJ, Kwak SJ, Kim EG
- KMID: 756231
- Exp Mol Med.
- 2009 Jun;41(6):387-396.
- doi: 10.3858/emm.2009.41.6.044
Angiotensin II (Ang II) stimulates migration of vascular smooth muscle cell (VSMC) in addition to its contribution to contraction and hypertrophy. It is well established that Rho GTPases regulate cellular... -
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- Granulocyte Colony Stimulating Factor Attenuates Hyperoxia-Induced Lung Injury by Down-Modulating Inflammatory Responses in Neonatal Rats
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Jeon GW, Sung DK, Jung YJ, Koo SH, Choi SH, Chang YS, Sin JB, Park WS
- KMID: 1106439
- Yonsei Med J.
- 2011 Jan;52(1):65-73.
- doi: 10.3349/ymj.2011.52.1.65
PURPOSE: Granulocyte colony stimulating factor (G-CSF) has been known to increase neutrophil production and have anti-inflammatory properties, but the effect of G-CSF on pulmonary system is in controversy. We investigated... -
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