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Effect of Panax Ginseng Alcohol Extract on Cardiovascular System

Hah JS, Kang BS, Kang DH

The effects of the alcohol extract of Panax ginseng on the myocardial contractility particularly with respect to Bowditch and Woodworth phenomena and the norepinephrine induced contraction of the vascular smooth...
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Myocardial Velocity Gradient during Low-dose Dobutamine Stress Echocardiography in the Predietion of viable Myoeardium in the Infarct Zone

Park DG, Sohn DW, Lee MY, Rhee MY, Chai IH, Seo JD, Lee YW

BACKGROUND: Clinical importance of predicting viability in the infarct zone has been well recognized and low dose dobutamine stress echocardiography has been used in this regards. Several experimental and clinical...
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Myocardial Functions Estimated by Pulsed Doppler Echocardiography in Patients with Chronic Renal Failure

Huh HJ, Choi BH, Hyun MC, Lee SB

  • KMID: 1662466
  • J Korean Pediatr Soc.
  • 1996 Dec;39(12):1717-1728.
PURPOSE: The objectives of this study were to estimate myocardial functions in patients with chronic renal failure by pulsed Doppler echocardiography, and investigate correlation between Doppler and disease parameters. METHODS: We...
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Segmental Tissue Doppler Image-Derived Tei Index in Patients With Regional Wall Motion Abnormalities

Baek HK, Park TH, Park JS, Seo JM, Park SY, Kim BG, Kim SO, Cha KS, Kim MH, Kim YD

BACKGROUND AND OBJECTIVES: Although the Tei index is a useful predictor of global ventricular function, it has not been investigated at the level of regional myocardial function. We therefore investigated...
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Relationship between sarcoplasmic reticular calcium release and Na+-Ca2+ exchange in the rat myocardial contraction

Kim EG, Kim SJ, Ko CM

  • KMID: 1580806
  • Korean J Physiol Pharmacol.
  • 2000 Jun;4(3):197-210.
Suppressive role of Na+-Ca2+ exchange in myocardial tension generation was examined in the negative frequency-force relationship (FFR) of electric field stimulated left atria (LA) from postnatal developing rat heart and in the whole-cell...
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The Direct Myocardial Depressant Effect of Naloxone in Vitro: Mechanical and Electrophysiological Actions

Kim KJ, Lee HC, Lee KY, Kim JY, Joo ST, Park WK

  • KMID: 2228619
  • Korean J Crit Care Med.
  • 2002 Nov;17(2):107-118.
BACKGROUND: Naloxone,an opioidant agonist, has been s hown t o have a c ar di ovascular pressor effect in states of hemorrhagic and endotoxic shock.We determined the direct inotropic effect...
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Acetaminophen Induced Cytotoxicity and Altered Gene Expression in Cultured Cardiomyocytes of H9C2 Cells

Jin SM, Park K

  • KMID: 2380178
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012011.
OBJECTIVES: Hepatotoxicity of acetaminophen has been widely studied. However, the adverse effects on the heart have not been sufficiently evaluated. This study was performed to investigate cytotoxicity and alterations of...
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Coronary Microembolization with Normal Epicardial Coronary Arteries and No Visible Infarcts on Nitrobluetetrazolium Chloride-Stained Specimens: Evaluation with Cardiac Magnetic Resonance Imaging in a Swine Model

Jin H, Yun H, Ma J, Chen Z, Chang S, Zeng M

OBJECTIVE: To assess magnetic resonance imaging (MRI) features of coronary microembolization in a swine model induced by small-sized microemboli, which may cause microinfarcts invisible to the naked eye. MATERIALS AND METHODS:...
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Catecholamines May Play an Important Role in the Pathogenesis of Transient Mid- and Basal Ventricular Ballooning Syndrome

Kim EM, Park JH, Park YS, Lee JH, Choi SW, Jeong JO, Seong IW

The exact pathogenesis of transient mid- and basal ventricular ballooning, a new variant of transient left ventricular (LV) ballooning, remains unknown. We report two cases of transient mid- and basal...
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Myocardial Depressant Effects of Sevoflurane: A comparative Study with Isoflurane on Mechanical and Electrophysiologic Effects In Vitro

Park WK, Suh CK

Dose-related depression of left ventricular function or cardiac output has been reported in humans and in vivo animal studies with sevoflurane (SEVO) anesthesia and myocardial depressant effect of SEVO appeared...
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Effects of Enflurane on the Left Ventricular Function in Isolated Diltiazem-Pretreated Rat Heart

Yoon HD, Lim SH, Yoon SM, Park YC

BACKGROUND: Calcium channel blockers and volatile anesthetics have depressant effects on cardiac function. Both of them appear to exert, qualitatively and quantitatively, different effects on myocardial contractility, coronary flow, and...
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Early Assessment of Myocardial Contractility by Contrast-Enhanced Magnetic Resonance (ceMRI) Imaging after Revascularization in Acute Myocardial Infarction (AMI)

Lim HE, Yong HS, Shin SH, Ahn JC, Seo HS, Oh DJ, Ro YM, Park CG

  • KMID: 1109519
  • Korean J Intern Med.
  • 2004 Dec;19(4):213-219.
BACKGROUND: Recent studies have demonstrated that the size and shape of the hyperenhanced areas on contrast-enhanced magnetic resonance imaging (ceMRI) were nearly identical to areas of irreversible injury, as defined...
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Effects of ryanodine on the intracellular Na+ activity and tension and action potentials of rat and guinea pig cardiac ventricular muscles

Suh CK, Park SR

Ryanodine has different effects on the contractility of rat and guinea pig ventricular muscle. Thus we investigated the effect of ryanodine on the intracellular Ca2+ and Na+ activities of the...
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Alteration of Left Ventricular Function with Dobutamine Challenge in Patients with Myocardial Bridge

Jhi JH, Cho KI, Ha JK, Jung CW, kim BJ, Park SO, Jo AR, Kim SM, Lee HG, Kim TI

BACKGROUND/AIMS: The aim of this study was to identify changes in left ventricular (LV) performance in patients with a myocardial bridge (MB) in the left anterior descending coronary artery during...
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The Effects of Desflurane on Ca2+ Release from the Myocardial Sarcoplasmic Reticulum in Vitro

Bai SJ, Lee YS, Shim JK, Kim JS, Moon JC, Nam YT

BACKGROUND: The purpose of this study is to examine the effect of Desflurane on myocardial contractility and cellular electrophysiologic behabior in isolated guinea pig and rat right ventricular papillary muscle. METHODS:...
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Effects of Inotropic Drugs on Mechanical Function and Oxygen Balance in Postischemic Canine Myocardium: Comparison of Dobutamine, Epinephrine, Amrinone, and Calcium Chloride

Yoo KY, Kim H, Jeong CW, Park HC, Bae HB, Lee JU

Brief ischemic episodes that induce myocardial and coronary endothelial dysfunction may alter the responses to inotropic drugs. To determine the effects of inotropic drugs in stunned myocardium, the coronary blood...
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Acute regional myocarditis with normal ventricular wall motion diagnosed by two-dimensional speckle tracking imaging

Ha SJ, Woo JS, Kwon SH, Oh CH, Kim KS, Bae JH, Kim WS

No abstract available.
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Antitumor profiles and cardiac electrophysiological effects of aurora kinase inhibitor ZM447439

Lee HA, Kwon M, Kim HA, Kim KS

Aurora kinases inhibitors, including ZM447439 (ZM), which suppress cell division, have attracted a great deal of attention as potential novel anti-cancer drugs. Several recent studies have confirmed the anti-cancer effects...
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Lipofundin(R) MCT/LCT 20% increase left ventricular systolic pressure in an ex vivo rat heart model via increase of intracellular calcium level

Park J, Kim YA, Han JY, Jin S, Ok SH, Sohn JT, Lee HK, Chung YK, Shin IW

BACKGROUND: Lipid emulsions have been used to treat various drug toxicities and for total parenteral nutrition therapy. Their usefulness has also been confirmed in patients with local anesthetic-induced cardiac toxicity....
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Impaired Coronary Flow Reserve Is the Most Important Marker of Viable Myocardium in the Myocardial Segment-Based Analysis of Dual-Isotope Gated Myocardial Perfusion Single-Photon Emission Computed Tomography

Lee WW, So Y, Kim KB, Lee DS

OBJECTIVE: The aim of this study was to investigate the most robust predictor of myocardial viability among stress/rest reversibility (coronary flow reserve [CFR] impairment), 201Tl perfusion status at rest, 201Tl...
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