- A Comparative Study of Magnetic-Activated Cell Sorting, Cytotoxicity and Preplating for the Purification of Human Myoblasts
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Park YG, Moon JH, Kim J
- KMID: 1110739
- Yonsei Med J.
- 2006 Apr;47(2):179-183.
- doi: 10.3349/ymj.2006.47.2.179
Although cultured myoblast transplantation has been extensively studied as a gene complementation approach to muscular dystrophy treatment, clinical success has still been limited. The inability to adequately isolate and purify... -
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- Cytoskeletons of Cultured Rat Fetal Muscle Cells
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Uhm CS, Lee DH, Kim H, Suh YS
- KMID: 2224595
- Korean J Anat.
- 1999 Feb;32(1):65-71.
Myoblasts fuse together to form multinucleated myotubes. However, only a few studies have been reported on the cytoskeletal changes during the fusion process. To understand the change of cytoskeleton during... -
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- Alteration of mitochondrial DNA content modulates antioxidant enzyme expressions and oxidative stress in myoblasts
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Min KH, Lee W
- KMID: 2461045
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):519-528.
- doi: 10.4196/kjpp.2019.23.6.519
Mitochondrial dysfunction is closely associated with reactive oxygen species (ROS) generation and oxidative stress in cells. On the other hand, modulation of the cellular antioxidant defense system by changes in... -
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- Isolation and Characterization of Human Muscle Cells
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Lee IH, Hung KP, Kim DY, Kim TH, Jun JB, Jung SS, Bae SC, Yoo DH, Kim SY
- KMID: 2025511
- J Korean Rheum Assoc.
- 1996 Jan;3(1):64-69.
OBJECTIVES: To isolate and culture of human muscle cells by manipulating culture conditions. METHODS: Muscle samples were obtained during total hip replacement or bedside muscle biopsy. We isolated myoblasts from freshly... -
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- Mitochondrial dysfunction reduces the activity of KIR2.1 K⺠channel in myoblasts via impaired oxidative phosphorylation
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Woo J, Kim HJ, Nam YR, Kim YK, Lee EJ, Choi I, Kim SJ, Lee W, Nam JH
- KMID: 2430092
- Korean J Physiol Pharmacol.
- 2018 Nov;22(6):697-703.
- doi: 10.4196/kjpp.2018.22.6.697
Myoblast fusion depends on mitochondrial integrity and intracellular Ca²⺠signaling regulated by various ion channels. In this study, we investigated the ionic currents associated with [Ca²âº]i regulation in normal and... -
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- A Possible Role of Kainate Receptors in C2C12 Skeletal Myogenic Cells
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Park JY, Han J, Hong SG
- KMID: 1607524
- Korean J Physiol Pharmacol.
- 2003 Dec;7(6):375-379.
Ca2+ influx appears to be important for triggering myoblast fusion. It remains, however, unclear how Ca2+ influx rises prior to myoblast fusion. Recently, several studies suggested that NMDA receptors may... -
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- Acetylcholine Induces Hyperpolarization Mediated by Activation of K (Ca) Channels in Cultured Chick Myoblasts
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Lee D, Han J, Park JY
- KMID: 2285308
- Korean J Physiol Pharmacol.
- 2005 Feb;9(1):37-43.
Our previous report demonstrated that chick myoblasts are equipped with Ca2+-permeable stretch- activated channels and Ca2+-activated potassium channels (KCa), and that hyperpolarization-induced by KCa channels provides driving force for Ca2+... -
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- Effects on Myoblast Proliferation by Fibroblast Growth Factor, Leukemia Inhibitory Factor and Interleukin-1
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Park YG
- KMID: 2136615
- J Korean Acad Rehabil Med.
- 2002 Aug;26(4):426-431.
OBJECTIVE: Recently, cultured myoblast transplantation has been extensively studied as a gene complementation approach in such genetic diseases as Duchenne muscular dystrophy (DMD). In the present work we investigated the... -
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- Expression and Localization of Laminin on Rectus Femoris Muscle in the Developing Rats
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Chung HS, Suh YK, Youn J, Kim WK, Paik DJ, Kim CK, Shin KS
- KMID: 2224570
- Korean J Anat.
- 2000 Jun;33(3):353-363.
Laminin is an extracellular matrix-associated protein, which is largely present in the basement membranes of the human placenta, striated muscle and Schwann cell. Laminin has been proposed to promote attachment,... -
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- TRPC3 cation channel plays an important role in proliferation and differentiation of skeletal muscle myoblasts
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Woo JS, Cho CH, Kim DH, Lee EH
- KMID: 983954
- Exp Mol Med.
- 2010 Sep;42(9):614-627.
- doi: 10.3858/emm.2010.42.9.061
During membrane depolarization associated with skeletal excitation-contraction (EC) coupling, dihydropyridine receptor [DHPR, a L-type Ca2+ channel in the transverse (t)-tubule membrane] undergoes conformational changes that are transmitted to ryanodine receptor... -
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- Injection of porous polycaprolactone beads containing autologous myoblasts in a dog model of fecal incontinence
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Kang SB, Lee HS, Lim JY, Oh SH, Kim SJ, Hong SM, Jang JH, Cho JE, Lee SM, Lee JH
- KMID: 2212466
- J Korean Surg Soc.
- 2013 Apr;84(4):216-224.
- doi: 10.4174/jkss.2013.84.4.216
PURPOSE: Few studies have examined whether bioengineering can improve fecal incontinence. This study designed to determine whether injection of porous polycaprolactone beads containing autologous myoblasts improves sphincter function in a... -
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- The maintenance ability and Ca²⺠availability of skeletal muscle are enhanced by sildenafil
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Huang M, Lee KJ, Kim KJ, Ahn MK, Cho CH, Kim DH, Lee EH
- KMID: 2367554
- Exp Mol Med.
- 2016 Dec;48(12):e278.
- doi: 10.1038/emm.2016.134
Sildenafil relaxes vascular smooth muscle cells and is used to treat pulmonary artery hypertension as well as erectile dysfunction. However, the effectiveness of sildenafil on skeletal muscle and the benefit... -
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- Selective Removal of Fibroblast with Using Proline Analogue and Cytosine Arabinoside in Myoblast Culture
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Park YG, Kim J, Shin JS, Moon JH
- KMID: 2323624
- J Korean Acad Rehabil Med.
- 2001 Jun;25(3):431-437.
OBJECTIVE: The phenomenon of fibroblast overgrowth is one of the major problems encountered during long-term culture such as myoblast culture. The first goal of the study is to determine the... -
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- p38 MAPK Participates in Muscle-Specific RING Finger 1-Mediated Atrophy in Cast-Immobilized Rat Gastrocnemius Muscle
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Kim J, Won KJ, Lee HM, Hwang BY, Bae YM, Choi WS, Song H, Lim KW, Lee CK, Kim B
- KMID: 2285386
- Korean J Physiol Pharmacol.
- 2009 Dec;13(6):491-496.
- doi: 10.4196/kjpp.2009.13.6.491
Skeletal muscle atrophy is a common phenomenon during the prolonged muscle disuse caused by cast immobilization, extended aging states, bed rest, space flight, or other factors. However, the cellular mechanisms... -
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- The Expression of Cytokines and Chemokine mRNA by Human Skeletal Muscle Cell Line (SKM14)
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Joo IS, Huh K, Lee YB, Kim SU
- KMID: 1616354
- J Korean Neurol Assoc.
- 2003 Feb;21(1):89-96.
BACKGROUND: Muscle is a target of immunological injury in several muscle diseases, such as idiopathic inflammatory myopathy. However, it is also a target for gene therapy. Therefore, it is important... -
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- Stem Cell Research in Cardiovascular System
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Choi SC, Lim DS
- KMID: 2030757
- Korean J Anat.
- 2004 Apr;37(2):133-140.
Myocardial infarction leads to loss of tissue and impairment of cardiac performance. Because cardiomyocytes have a limited ability to self-renewal, and thus the transplantation of adult stem cells into infarcted... -
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- Ultrastructural Study on the Development of Ciliary Body in Human Fetuses
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Lee MK, Park YG, Lim IS, Park BI, Yoon JR
- KMID: 2147828
- J Korean Ophthalmol Soc.
- 1995 Feb;36(2):253-264.
Morphological development of the ciliary body was studied by electron microscope in human fetuses from 50 to 260 mm crown-rump length(11-30 weeks of gestational age). At a 50 mm(11 weeks)... -
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- Sumoylation of histone deacetylase 1 regulates MyoD signaling during myogenesis
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Joung H, Kwon S, Kim KH, Lee YG, Shin S, Kwon DH, Lee YU, Kook T, Choe N, Kim JC, Kim YK, Eom GH, Kook H
- KMID: 2438357
- Exp Mol Med.
- 2018 Jan;50(1):e427.
- doi: 10.1038/emm.2017.236
Sumoylation, the conjugation of a small ubiquitin-like modifier (SUMO) protein to a target, has diverse cellular effects. However, the functional roles of the SUMO modification during myogenesis have not been... -
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- S100 and p65 expression are increased in the masseter muscle after botulinum toxin-A injection
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Park YW, Kim SG, Jo YY
- KMID: 2351667
- Maxillofac Plast Reconstr Surg.
- 2016 Aug;38(8):33.
- doi: 10.1186/s40902-016-0079-8
BACKGROUND: The purpose of this study was to compare the expression levels of p65 and S100 in the rat masseter muscle after the injection of different concentrations of botulinum toxin-A... -
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- Current Concepts in Stem Cell Therapy for Cardiovascular Diseases: What We Know and Don't Know
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Jeon KH
- KMID: 2129478
- Hanyang Med Rev.
- 2015 Nov;35(4):242-249.
- doi: 10.7599/hmr.2015.35.4.242
Medical therapies and mechanical interventions for the treatment of myocardial infarction (MI) and ischemic heart failure have seen great progress. However, current therapies only slow the progression to heart failure,... -
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