- Regulation of the Collagen Gene Expression
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Lee KS
- KMID: 2230752
- Korean J Dermatol.
- 1995 Dec;33(6):1005-1013.
The genes that codify the subunits of the fibril-forming collagen constitute an evolutionarily related group within the collagen multigene family, Deposition of fibrillar molecules in the extrcellular matrix of several... -
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- Phylogenetically interrelated ETS genes, ETV1, ERM and E1A-F locate on different chromosomes
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Jeon IS, Shapiro DN
- KMID: 1038161
- J Korean Med Sci.
- 1998 Aug;13(4):355-360.
- doi: 10.3346/jkms.1998.13.4.355
ETV1, ERM and E1A-F are members of the multigene ETS domain containing a class of transcription factors, first identified in the genome of the avian retrovirus E26. Based upon... -
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- Regulation of Immune Responses by the Activating and Inhibitory Myeloid-Associate Immunoglobuline-Like Receptors (MAIR) (CD300)
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Shibuya A, Nakahashi-Oda C, Tahara-Hanaoka S
- KMID: 1474593
- Immune Netw.
- 2009 Apr;9(2):41-45.
- doi: 10.4110/in.2009.9.2.41
Activating and inhibitory cell surface receptors play important roles in regulation of immune responses. Recent progress has demonstrated that many inhibitory receptors pair with activating, as well as inhibitory, isoforms,... -
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- Cloning of BNIP3h, a member of proapoptotic BNIP3 family genes
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Farooq M, Kim YH, Im SU, Chung EJ, Hwang SY, Sohn MY, Kim MK, Kim JC
- KMID: 938882
- Exp Mol Med.
- 2001 Sep;33(3):169-173.
Apoptosis is regulated by interaction of antiapoptotic Bcl-2 family proteins with various proapoptotic proteins, several of which are also members of the Bcl-2 family. BNIP3 (formerly NIP3) is a proapoptotic... -
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- Erratum: The Effect of Lowering the Threshold for Diagnosis of Impaired Fasting Glucose
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Kim SH, Shim WS, Kim EA, Kim EJ, Lee SH, Hong SB, Kim YS, Park SG, Leem JH, Lee HJ, Nam M
- KMID: 1793210
- Yonsei Med J.
- 2008 Aug;49(4):687-687.
- doi: 10.3349/ymj.2008.49.4.687
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- Oligoadenylate synthase-like (OASL) proteins: dual functions and associations with diseases
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Choi UY, Kang JS, Hwang YS, Kim YJ
- KMID: 2155409
- Exp Mol Med.
- 2015 Mar;47(3):e144.
- doi: 10.1038/emm.2014.110
The study of antiviral pathways to reveal methods for the effective response and clearance of virus is closely related to understanding interferon (IFN) signaling and its downstream target genes, IFN-stimulated... -
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- The effect of glutathione S-transferase M1 and T1 polymorphisms on blood pressure, blood glucose, and lipid profiles following the supplementation of kale (Brassica oleracea acephala) juice in South Korean subclinical hypertensive patients
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Han JH, Lee HJ, Kim TS, Kang MH
- KMID: 2313809
- Nutr Res Pract.
- 2015 Feb;9(1):49-56.
- doi: 10.4162/nrp.2015.9.1.49
BACKGROUND/OBJECTIVES: Glutathione S-transferase (GST) forms a multigene family of phase II detoxification enzymes which are involved in the detoxification of reactive oxygen species. This study examines whether daily supplementation of... -
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- Therapeutic Modulation of Apoptosis: Targeting the BCL-2 Family at the Interface of the Mitochondrial Membrane
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Nemec KN, Khaled AR
- KMID: 2158185
- Yonsei Med J.
- 2008 Oct;49(5):689-697.
- doi: 10.3349/ymj.2008.49.5.689
A vast portion of human disease results when the process of apoptosis is defective. Disorders resulting from inappropriate cell death range from autoimmune and neurodegenerative conditions to heart disease. Conversely,... -
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- Effects of glutathione s-transferase (GST) M1 and T1 polymorphisms on antioxidant vitamins and oxidative stress-related parameters in Korean subclinical hypertensive subjects after kale juice (Brassica oleracea acephala) supplementation
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Lee HJ, Han JH, Park YK, Kang MH
- KMID: 2407808
- Nutr Res Pract.
- 2018 Apr;12(2):118-128.
- doi: 10.4162/nrp.2018.12.2.118
BACKGROUND/OBJECTIVES: Glutathione s-transferase (GST) is involved in the formation of a multigene family comprising phase II detoxification enzymes, involved in the detoxification of reactive oxygen species. This study evaluated whether... -
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- Computational Approach for Biosynthetic Engineering of Post-PKS Tailoring Enzymes
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Kim KB, Park K
- KMID: 2166423
- Genomics Inform.
- 2008 Dec;6(4):227-230.
Compounds of polyketide origin possess a wealth of pharmacological effects, including antibacterial, antifungal, antiparasitic, anticancer and immunosuppressive activities. Many of these compounds and their semisynthetic derivatives are used today in... -
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- Lymphocyte DNA damage and plasma antioxidant status in Korean subclinical hypertensive patients by glutathione S-transferase polymorphism
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Han JH, Lee HJ, Choi HJ, Yun KE, Kang MH
- KMID: 2407769
- Nutr Res Pract.
- 2017 Jun;11(3):214-222.
- doi: 10.4162/nrp.2017.11.3.214
BACKGROUND/OBJECTIVES: Glutathione S-transferase (GST) forms a multigene family of phase II detoxification enzymes which are involved in the detoxification of xenobiotics by conjugating substances with glutathione. The aim of this... -
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- Rhox in mammalian reproduction and development
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Lee SE, Lee SY, Lee KA
- KMID: 2167500
- Clin Exp Reprod Med.
- 2013 Sep;40(3):107-114.
- doi: 10.5653/cerm.2013.40.3.107
Homeobox genes play essential roles in embryonic development and reproduction. Recently, a large cluster of homeobox genes, reproductive homeobox genes on the X chromosome (Rhox) genes, was discovered as three... -
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- Lymphocyte DNA Damage and Anti-Oxidative Parameters are Affected by the Glutathione S-Transferase (GST) M1 and T1 Polymorphism and Smoking Status in Korean Young Adults
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Han JH, Lee HJ, Kang MH
- KMID: 2268560
- Korean J Nutr.
- 2011 Oct;44(5):366-377.
- doi: 10.4163/kjn.2011.44.5.366
Glutathione S-transferase (GST) is a multigene family of phase II detoxifying enzymes that metabolize a wide range of exogenous and endogenous electrophilic compounds. GSTM1 and GSTT1 gene polymorphisms may account... -
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- Streptomyces Cytochrome P450 Enzymes and Their Roles in the Biosynthesis of Macrolide Therapeutic Agents
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Cho MA, Han S, Lim YR, Kim V, Kim H, Kim D
- KMID: 2442003
- Biomol Ther.
- 2019 Feb;27(2):127-133.
- doi: 10.4062/biomolther.2018.183
The study of the genus Streptomyces is of particular interest because it produces a wide array of clinically important bioactive molecules. The genomic sequencing of many Streptomyces species has revealed... -
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- PathTalk: Interpretation of Microarray Gene-Expression Clusters in Association with Biological Pathways
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Chung TS, Chung HJ, Kim JH
- KMID: 2166267
- Genomics Inform.
- 2007 Sep;5(3):124-128.
Microarray technology enables us to measure the expression of tens of thousands of genes simultaneously under various experimental conditions. Clustering analysis is one of the most successful methods for analyzing... -
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- RFLP Haplotypes of beta-Globin Gene Complex of beta-Thalassemic Chromosomes in Koreans
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Lee YJ, Park SS, Kim JY, Cho HI
- KMID: 1109754
- J Korean Med Sci.
- 2002 Aug;17(4):475-478.
- doi: 10.3346/jkms.2002.17.4.475
Korea is in the low-prevalence area of beta-thalassemia and the Korean population has relatively homogenous racial characteristics. Recently, we identified some causative mutations of the Korean beta-thalassemia patients. In order... -
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- Genes Involved in the Biosynthesis and Transport of Acinetobactin in Acinetobacter baumannii
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Hasan T, Choi CH, Oh MH
- KMID: 2053330
- Genomics Inform.
- 2015 Mar;13(1):2-6.
- doi: 10.5808/GI.2015.13.1.2
Pathogenic bacteria survive in iron-limited host environments by using several iron acquisition mechanisms. Acinetobacter baumannii, causing serious infections in compromised patients, produces an iron-chelating molecule, called acinetobactin, which is composed... -
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- A Novel Translocation Involving RUNX1 and HOXA Gene Clusters in a Case of Acute Myeloid Leukemia with t(7;21)(p15;q22)
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Moon Y, Horsman DE, Humphries , Park G
- KMID: 1493618
- Immune Netw.
- 2013 Oct;13(5):222-226.
- doi: 10.4110/in.2013.13.5.222
Translocations involving chromosome 21q22 are frequently observed in hematologic malignancies including acute myeloid leukemia (AML), most of which have been known to be involved in malignant transformation through transcriptional dysregulation... -
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- DNA Microarray Analysis of Gene Expression Profiles in Aging process of Mouse Brain
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Lee MS, Heo JI, Kim JB, Park JB, Lee JY, Han JA, Kim JI
- KMID: 2166191
- Genomics Inform.
- 2006 Mar;4(1):23-32.
In order to investigate the molecular basis of the aging process in brain, we have employed high-density oligonucleotide microarrays providing data on 10,108 gene clusters to define transcriptional patterns in... -
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- Functional proteomics, human genetics and cancer biology of GIPC family members
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Katoh M
- KMID: 2154245
- Exp Mol Med.
- 2013 Jun;45(6):e26.
GIPC1, GIPC2 and GIPC3 consist of GIPC homology 1 (GH1) domain, PDZ domain and GH2 domain. The regions around the GH1 and GH2 domains of GIPC1 are involved in dimerization... -
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