- Seizure Induced Alteration of Microtubule Associated Proteins Immunoreactivities in the Mongolian Gerbil Striatum
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An SJ, Park SK, Hwang IK, Won MH, Kang TC
- KMID: 1559379
- Korean J Anat.
- 2002 Oct;35(5):411-418.
The present study involves a chronological and comparative analysis of both microtubule-associated protein 1A (MAP1A) and microtubule-associated protein 2 (MAP2) immunoreactivities in the striatum of both seizure resistant (SR) and... -
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- Microtubular Dysfunction and Male Infertility
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Gunes S, Sengupta P, Henkel R, Alguraigari A, Sinigaglia MM, Kayal M, Joumah A, Agarwal A
- KMID: 2465406
- World J Mens Health.
- 2020 Jan;38(1):9-23.
- doi: 10.5534/wjmh.180066
Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain functional capacity of... -
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- Molecular Motor Proteins of the Kinesin Superfamily Proteins (KIFs): Structure, Cargo and Disease
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Seog DH, Lee DH, Lee SK
- KMID: 1785685
- J Korean Med Sci.
- 2004 Feb;19(1):1-7.
- doi: 10.3346/jkms.2004.19.1.1
Intracellular organelle transport is essential for morphogenesis and functioning of the cell. Kinesins and kinesin-related proteins make up a large superfamily of molecular motors that transport cargoes such as vesicles,... -
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- Dysembryoplastic Neuroepithelial Tumors
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Suh YL
- KMID: 2381403
- J Pathol Transl Med.
- 2015 Nov;49(6):438-449.
- doi: 10.4132/jptm.2015.10.05
Dysembryoplastic neuroepithelial tumor (DNT) is a benign glioneuronal neoplasm that most commonly occurs in children and young adults and may present with medically intractable, chronic seizures. Radiologically, this tumor is... -
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- Sciatic nerve leachate of cattle causes neuronal differentiation of PC12 cells via ERK1/2 signaling pathway
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Zhang Z, Liu Y, Zhu X, Wei L, Zhu J, Shi K, Wang G, Pan L
- KMID: 2417566
- J Vet Sci.
- 2018 Jul;19(4):512-518.
- doi: 10.4142/jvs.2018.19.4.512
Previous studies have shown that the sciatic nerve has neurotrophic activity, and nerve regeneration, differentiation, and axon outgrowth can be modulated by different sciatic nerve preparations. However, numerous animals may... -
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- Autophagy Activity in Pulmonary Metastatic Tumor Tissues from Colorectal Cancer: A Pilot Study
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Kim YS, Shin JH, Bae MK, Lee CY, Kim DJ, Chung KY, Lee JG
- KMID: 2070194
- Yonsei Med J.
- 2014 Nov;55(6):1484-1488.
- doi: 10.3349/ymj.2014.55.6.1484
PURPOSE: Autophagy has been reported to be involved in treatment failure in tumor. We aimed to evaluate autophagy activity in tumor tissue and compare them between the recurrence and non-recurrence... -
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- Autophagy of Human Tenon's Capsule Fibroblasts Induced by Mitomycin-C
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Park C, Park R, Ryu SK, Lee DW
- KMID: 2338022
- J Korean Ophthalmol Soc.
- 2011 Nov;52(11):1337-1343.
PURPOSE: The present study investigated whether an autophagic process is involved in the apoptotic death of human tenon's capsule fibroblasts (HTCFs) caused by mitomycin-C. METHODS: An autophagic phenotype was tested using... -
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- Anti-tumor mechanisms and regulation of survivin by selective cyclooxygenase-2 inhibitor
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Jang JW
- KMID: 1381460
- Korean J Hepatol.
- 2008 Sep;14(3):305-308.
- doi: 10.3350/kjhep.2008.14.3.305
No abstract available. -
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- Neuronal Cytoskeletal Abnormalities and Neurotrophin Receptor Immunoreactivity in Severe Cerebral Cortical Dysplasia
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Kim JY, Roh JK, Chung CK
- KMID: 2186049
- J Korean Neurol Assoc.
- 2000 Mar;18(2):199-210.
BACKGROUND: Cerebral cortical dysplasia (CD) is one of the important causes of intractable epilepsies and characterized histologically by disorganized cortical lamination and cytomegalic dysplastic neurons. Although various cytoskeletal abnormalities have... -
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- Oleanolic acid induced autophagic cell death in hepatocellular carcinoma cells via PI3K/Akt/mTOR and ROS-dependent pathway
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Shi Y, Song Q, Hu D, Zhuang X, Yu S, Teng D
- KMID: 2285595
- Korean J Physiol Pharmacol.
- 2016 May;20(3):237-243.
- doi: 10.4196/kjpp.2016.20.3.237
Oleanolic acid (OA) has a wide variety of bioactivities such as hepatoprotective, anti-inflammatory and anti-cancer activity and is used for medicinal purposes in many Asian countries. In the present study,... -
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- Expression of cyclin-dependent kinase inhibitor p27kip1 in malignant lymphomas
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Oh YH, Park CK
- KMID: 1730635
- J Korean Med Sci.
- 2000 Aug;15(4):399-406.
- doi: 10.3346/jkms.2000.15.4.399
p27kip1 is a cyclin-dependent kinase inhibitor that regulates progression from G1 into S phase. Aberrations in cell cycle control are often observed in tumors d might even be necessary in... -
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- Characteristics of amniotic fluid derived stem cells with trisomy 21
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Choi KM, Im EH, Cho JA, Lee SJ, Park H, Shin BS, Lee JH, Choi JS, Lee KW
- KMID: 2078000
- Korean J Obstet Gynecol.
- 2010 Sep;53(9):825-832.
- doi: 10.5468/kjog.2010.53.9.825
OBJECTIVE: To assess molecular markers of amniotic fluid derived stem cells (AFSCs) in aspects of increased neurological deficit in Down syndrome. METHODS: Amniotic fluid samples through amniocentesis for prenatal diagnosis from... -
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- Expression of Heat Shock Protein 70 Modulates the Chemoresponsiveness of Pancreatic Cancer
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Hyun JJ, Lee HS, Keum B, Seo YS, Jeen YT, Chun HJ, Um SH, Kim CD
- KMID: 1712336
- Gut Liver.
- 2013 Nov;7(6):739-746.
BACKGROUND/AIMS: Heat shock protein (HSP) 70 is constitutively overexpressed in pancreatic cancer cells (PCCs) and appears to confer protection against chemotherapeutics. We investigated whether modulating HSP 70 increases chemoresponsiveness to... -
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- Identification of Differentially Expressed Genes in Bovine Follicular Cystic Ovaries
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Choe C, Cho YW, Kim CW, Son DS, Han J, Kang D
- KMID: 2071692
- Korean J Physiol Pharmacol.
- 2010 Oct;14(5):265-272.
- doi: 10.4196/kjpp.2010.14.5.265
Follicular cystic ovary (FCO) is one of the most frequently diagnosed ovarian diseases and is a major cause of reproductive failure in mammalian species. However, the mechanism by which FCO... -
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- Mutation and expression of the p27KIP1 and p57KIP2 genes in human gastric cancer
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Shin JY, Kim HS, Lee KS, Kim JB, Park JB, Won MH, Chae SW, Choi YH, Choi KC, Park YE, Lee JY
- KMID: 1109306
- Exp Mol Med.
- 2000 Jun;32(2):79-83.
Cyclin-dependent kinase inhibitors (CDKI) are negative regulators of cell cycle progression by binding the cyclin-CDK complex and inhibiting the CDK activity. Genetic alteration in the CDKI genes has been implicated... -
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- Neurogenic differentiation of human dental stem cells in vitro
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Lee JH, Um S, Song IS, Kim HY, Seo BM
- KMID: 2005442
- J Korean Assoc Oral Maxillofac Surg.
- 2014 Aug;40(4):173-180.
- doi: 10.5125/jkaoms.2014.40.4.173
OBJECTIVES: The purpose of this study was to investigate the neurogenic differentiation of human dental pulp stem cells (DPSCs), periodontal ligament stem cells (PDLSCs), and stem cells from apical papilla... -
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- Inhibition of autophagy protein LC3A as a therapeutic target in ovarian clear cell carcinomas
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Miyamoto M, Takano M, Aoyama T, Soyama H, Yoshikawa , Tsuda H, Furuya K
- KMID: 2413444
- J Gynecol Oncol.
- 2017 May;28(3):e33.
- doi: 10.3802/jgo.2017.28.e33
OBJECTIVE: Ovarian clear cell carcinoma (CCC) is one of histological subtypes showing poor prognosis due to chemoresistance. The association of autophagy-related proteins and clinical implementation in CCC has not been... -
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- Molecules and their functions in autophagy
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Pyo JO, Nah J, Jung YK
- KMID: 1120125
- Exp Mol Med.
- 2012 Feb;44(2):73-80.
- doi: 10.3858/emm.2012.44.2.029
Autophagy is a self-degradation system of cellular components through an autophagosomal-lysosomal pathway. Over the last 15 yr, yeast genetic screens led to the identification of a number of genes involved... -
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- The Combined Effects of Ginkgo Biloba Extracts and Aspirin on Viability of SK-N-MC, Neuroblastoma Cell Line in Hypoxia and Reperfusion Condition
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Moon SH, Lee YJ, Park SY, Song KY, Kong MH, Kim JH
- KMID: 1442687
- J Korean Neurosurg Soc.
- 2011 Jan;49(1):13-19.
- doi: 10.3340/jkns.2011.49.1.13
OBJECTIVE: The purpose of this study is to investigate the combined effects of ginkgo biloba extract, ginkgolide A and B and aspirin on SK-N-MC, human neuroblastoma cell viability and mRNA... -
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- Involvement of ROS in Curcumin-induced Autophagic Cell Death
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Lee YJ, Kim NY, Suh YA, Lee C
- KMID: 2389102
- Korean J Physiol Pharmacol.
- 2011 Feb;15(1):1-7.
Many anticancer agents as well as ionizing radiation have been shown to induce autophagy which is originally described as a protein recycling process and recently reported to play a crucial... -
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