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Micronucleus test as an index of mutagenicity for workers exposed to chromium

Yoon HR, Kim JR, Hong DY

  • KMID: 1694509
  • Korean J Occup Environ Med.
  • 1993 Feb;5(1):45-57.
No abstract available.
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A Review on Mutagenicity Testing for Hazard Classification of Chemicals at Work: Focusing on in vivo Micronucleus Test for Allyl Chloride

Rim KT, Kim SJ

Chemical mutagenicity is a major hazard that is important to workers' health. Despite the use of large amounts of allyl chloride, the available mutagenicity data for this chemical remains controversial....
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Cytogenetic Radiation Adaptive Response Assessed by Metaphase Analysis and Micronuclei Test in Human Lymphocytes and Mouse Bone Marrow Cells

Min JJ, Bom HS, Lee SY, Choi KH, Jeong HJ, Song HC, Kim JY

  • KMID: 1566920
  • Korean J Nucl Med.
  • 1998 Dec;32(6):525-533.
PURPOSE: Radiation adaptive response in human peripheral lymphocytes and mouse bone marrow cells was investigated using both metaphase analysis and micronucleus assay. We assessed the correlation between both tests. MATERIALS...
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A Study of Micronucleus Induction with Methyl Formate and 2-Methylbutane in Bone Marrow Cells of Male ICR Mice

Kim SJ, Rim KT, Kang MG, Kim JK, Chung YH, Yang JS

  • KMID: 2316979
  • Saf Health Work.
  • 2010 Sep;1(1):80-86.
OBJECTIVES: We investigated the genotoxicity of two chemicals, methyl formate and 2-methylbutane, using male ICR mice bone marrow cells for the screening of micronucleus induction. Although these two chemicals have...
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Genotoxicity Assessment of Erythritol by Using Short-term Assay

Chung YS, Lee M

  • KMID: 2317843
  • Toxicol Res.
  • 2013 Dec;29(4):249-255.
Erythritol is a sugar alcohol that is widely used as a natural sugar substitute. Thus, the safety of its usage is very important. In the present study, short-term genotoxicity assays...
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Lack of Mutagenicity Potential of Periploca sepium Bge. in Bacterial Reverse Mutation (Ames) Test, Chromosomal Aberration and Micronucleus Test in Mice

Zhang MS, Bang IS, Park CB

  • KMID: 2380181
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012014.
OBJECTIVES: The root barks of Periploca sepium Bge. (P. sepium) has been used in traditional Chinese medicine for healing wounds and treating rheumatoid arthritis. However, toxicity in high-doses was often...
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Development of a Noble Dosimetry Using Metaphase Analysis and Micronuclei Assay of Bone Marrow Cells in Mice

Min JJ, Bom HS, Kim YH, Yoon HJ, Kim JY

  • KMID: 1991076
  • Korean J Nucl Med.
  • 2000 Feb;34(1):74-81.
PURPOSE: The purpose of this study was to develop in vivo dosimetries using both chromosomal aberrations and micronuclei in mice to assess biological effects of radiations. MATERIALS AND METHODS: Five each...
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The micronucleus frequency in cytokinesis-blocked lymphocytes of cattle in the vicinity of a nuclear power plant

Lee HJ, Kang CM, Kim SR, Kim JC, Bae CS, Oh KS, Jo SK, Kim TH, Jang JS, Kim SH

Cytogenetic and hematological analyses were performed on the peripheral blood lymphocytes (PBLs) obtained from Korean native cattle bred in the vicinity of three nuclear power plants (Wolsong, Uljin and Yeonggwang)...
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Appropriate In Vitro Methods for Genotoxicity Testing of Silver Nanoparticles

Kim HR, Park YJ, Shin DY, Oh SM, Chung KH

  • KMID: 2380115
  • Environ Health Toxicol.
  • 2013 ;28(1):e2013003.
OBJECTIVES: We investigated the genotoxic effects of 40-59 nm silver nanoparticles (Ag-NPs) by bacterial reverse mutation assay (Ames test), in vitro comet assay and micronucleus (MN) assay. In particular, we...
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Comparative evaluation of the mutagenicity and genotoxicity of smoke condensate derived from Korean cigarettes

Kim HR, Lee JE, Jeong MH, Choi SJ, Lee K, Chung KH

OBJECTIVES: Cigarette smoking is associated with carcinogenesis owing to the mutagenic and genotoxic effects of cigarette smoke. The aim of this study was to evaluate the mutagenic and genotoxic effects...
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Evaluation of the genotoxicity and cytotoxicity in the buccal epithelial cells of patients undergoing orthodontic treatment with three light-cured bonding composites by using micronucleus testing

Toy E, Yuksel S, Ozturk F, Karatas OH, Yalcin M

OBJECTIVE: This study evaluated the cytotoxicity and genotoxicity of fixed orthodontic treatment with three different light-cured orthodontic bonding composites by analyzing micronucleus (MN) formation in the buccal mucosa during a...
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Genotoxicity and toxicological effects of acrylamide on reproductive system in male rats

Yang HJ, Lee SH, Jin Y, Choi JH, Han CH, Lee MH

  • KMID: 1114850
  • J Vet Sci.
  • 2005 Jun;6(2):103-109.
The toxicity of acrylamide was evaluated through mutagenicity of Salmonella, chromosome aberration of Chinese hamster lung fibroblasts, micronucleus formation in mice and reproductive toxicity in rats. Based on Ames test,...
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Evaluation of in vitro and in vivo genotoxicity of Angelica acutiloba in a standard battery of assays

Yun JW, Kim YS, Kwon E, Kim SH, You JR, Kim HH, Che JH, Kang BC

Among three representative species of Angelica found in Asian countries, including Korea, China, and Japan, Angelica acutiloba (AA) has been used as traditional herbal medicine with antitumor, anti-inflammatory, anti-obesity, and...
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Response of Odontoblast to the Bio-Calcium Phosphate Cement

Kim JW, Kim SW, Kim GC, Kim YD, Kim CH, Kim BJ, Kim UK

  • KMID: 2009671
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2011 Jul;33(4):301-307.
PURPOSE: If the tooth structure is damaged, then it is impossible to regenerate the tooth. The materials used to restore the tooth structure are not related to the composition of...
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Experimental modeling of the acute toxicity and cytogenotoxic fate of composite mixtures of chromate, copper and arsenate oxides associated with CCA preservative using Clarias gariepinus (Burchell 1822)

Fagbenro O, Alimba CG, Bakare AA

Concurrent occurrence of chromium (Cr), copper (Cu) and arsenic (As) from chromated copper arsenate (CCA) wood preservative in aquatic ecosystems demands that their joint-actions in eliciting toxic effects be assessed...
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Radioprotective effect of mefenamic acid against radiation-induced genotoxicity in human lymphocytes

Hosseinimehr SJ, Nobakht R, Ghasemi A, Pourfallah TA

PURPOSE: Mefenamic acid (MEF) as a non-steroidal anti-inflammatory drug is used as a medication for relieving of pain and inflammation. Radiation-induced inflammation process is involved in DNA damage and cell...
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The Role of p53 in Marijuana Smoke Condensates-induced Genotoxicity and Apoptosis

Kim HR, Son BH, Lee SY, Chung KH, Oh SM

  • KMID: 2380184
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012017.
OBJECTIVES: Marijuana is one of the most frequently abused drug in Korea and its adverse health effects are controversial. p53 is known to be crucial in regulating the DNA damage...
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Interaction between odontoblast and bio-calcium phosphate cement reinforced with chitosan

Chun BD, Kim SW, Lee ST, Kim TH, Lee JH, Kim GC, Kim YD, Kim UK

  • KMID: 2328616
  • J Korean Assoc Oral Maxillofac Surg.
  • 2011 Oct;37(5):415-420.
PURPOSE: Calcium phosphate cement (CPC) is one of many useful materials for restoring tooth defects, periodontium and maxillofacial area. Chitosan is a biodegradable material that has been shown to promote...
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Evaluation of General Toxicity and Genotoxicity of the Silkworm Extract Powder

Heo HS, Choi JH, Oh JJ, Lee WJ, Kim SS, Lee DH, Lee HK, Song SW, Kim KH, Choi YK, Ryu KS, Kang BH

  • KMID: 2317845
  • Toxicol Res.
  • 2013 Dec;29(4):263-278.
The silkworm extract powder contain 1-deoxynojirimycin (DNJ), a potent alpha-glycosidase inhibitor, has therapeutic potency against diabetes mellitus. Therefore, natural products containing DNJ from mulberry leaves and silkworm are consumed as...
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Frequencies of Micronuclei in Peripheral Lymphocytes in Korean Populations after Chronic Low-dose Radiation Exposure

An MY, Kim TH

  • KMID: 1095124
  • J Vet Sci.
  • 2002 Sep;3(3):213-218.
The purpose of this study was to estimate predictive markers of intrinsic radiosensitivity in individuals who were exposed to occupational or environmental radiation. Throughout this process, the actual biohazard risks...
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