- Metabolomics 2014 Tenth annual international conference of the metabolomics society
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Kim AH, Cho JY
- KMID: 2050936
- Transl Clin Pharmacol.
- 2014 Dec;22(2):55-57.
- doi: 10.12793/tcp.2014.22.2.55
No abstract available. -
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- Metabolomics Goes to Work for You
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Kim KH
- KMID: 2232935
- Int Neurourol J.
- 2014 Sep;18(3):104-104.
- doi: 10.5213/inj.2014.18.3.104
No abstract available. -
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- Metabolomics Research in Kidney Transplantation
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Lee YH, Lee SH
- KMID: 2324351
- J Korean Soc Transplant.
- 2015 Jun;29(2):49-53.
- doi: 10.4285/jkstn.2015.29.2.49
Acute and chronic immune injury, drug toxicity, and cardiovascular complications remain a critical challenge following kidney transplantation. Success from these hurdles is closely associated with the ability to monitor patients... -
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- Application of Metabolomics to Quality Control of Natural Product Derived Medicines
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Lee KM, Jeon JY, Lee BJ, Lee H, Choi HK
- KMID: 2395804
- Biomol Ther.
- 2017 Nov;25(6):559-568.
- doi: 10.4062/biomolther.2016.249
Metabolomics has been used as a powerful tool for the analysis and quality assessment of the natural product (NP)-derived medicines. It is increasingly being used in the quality control and... -
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- Understanding Metabolomics in Biomedical Research
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Kim SJ, Kim SH, Kim JH, Hwang S, Yoo HJ
- KMID: 2169686
- Endocrinol Metab.
- 2016 Mar;31(1):7-16.
- doi: 10.3803/EnM.2016.31.1.7
The term "omics" refers to any type of specific study that provides collective information on a biological system. Representative omics includes genomics, proteomics, and metabolomics, and new omics is constantly... -
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- Pharmacometabolomics: Current Applications and Future Perspectives
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Kim HJ, Yoon YR
- KMID: 2317851
- Transl Clin Pharmacol.
- 2014 Jun;22(1):8-10.
Metabolomics, a novel "omics" platform, is a powerful tool for the discovery of clinically useful biomarkers and biochemical processes to improve diagnosis and therapy. Through the use of advanced analytical... -
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- Metabolomics strategies to discover new biomarkers associated to severe allergic phenotypes
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Barber D, Villaseñor A, Escribese
- KMID: 2461109
- Asia Pac Allergy.
- 2019 Oct;9(4):e37.
- doi: 10.5415/apallergy.2019.9.e37
In the last decades have emerged new technological platforms that allow evaluation of genes, transcripts, proteins, or metabolites of a living being, so-called omics sciences. More importantly, new technics for... -
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- Metabolomics: A Novel Approach to Early and Noninvasive Prostate Cancer Detection
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Roberts MJ, Schirra HJ, Lavin MF, Gardiner R
- KMID: 2315629
- Korean J Urol.
- 2011 Feb;52(2):79-89.
Prostate cancer (PCa) is the most commonly diagnosed visceral cancer in men and is responsible for the second highest cancer-related male mortality rate in Western countries, with increasing rates being... -
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- Pathogenesis of endothelial cell dysfunction in chronic kidney disease: a retrospective and what the future may hold
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Goligorsky MS
- KMID: 2381521
- Kidney Res Clin Pract.
- 2015 Jun;34(2):76-82.
- doi: 10.1016/j.krcp.2015.05.003
Cardiovascular complications dominate the landscape of chronic kidney diseases (CKD). Endothelial cell dysfunction (ECD) is a well-known culprit of cardiovascular morbidity and it develops in CKD with remarkable frequency. This... -
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- Metabolomics Insights Into Pathophysiological Mechanisms of Interstitial Cystitis
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Fiehn O, Kim J
- KMID: 2232937
- Int Neurourol J.
- 2014 Sep;18(3):106-114.
- doi: 10.5213/inj.2014.18.3.106
Interstitial cystitis (IC), also known as painful bladder syndrome or bladder pain syndrome, is a chronic lower urinary tract syndrome characterized by pelvic pain, urinary urgency, and increased urinary frequency... -
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- Metabolomic Study of a Diagnostic Model for the Metabolites of Stool Fat
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Lee CH, Kim J, Ahn SY, Lee SY
- KMID: 1775781
- Korean J Gastroenterol.
- 2013 Jan;61(1):9-16.
- doi: 10.4166/kjg.2013.61.1.9
BACKGROUND/AIMS: Metabolomics is a powerful tool for measuring low-molecular-weight metabolites in an organism at a specified time under specific environmental conditions. The aim of this study was to determine the... -
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- Metabolomics Approach to Explore the Effects of Rebamipide on Inflammatory Arthritis Using Ultra Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry
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Moon SJ, Lee SH, Jung BH, Min JK
- KMID: 2389060
- J Rheum Dis.
- 2017 Aug;24(4):192-202.
- doi: 10.4078/jrd.2017.24.4.192
OBJECTIVE: Rebampide is a gastroprotective agent used to treat gastritis. It possesses anti-inflammatory and anti-arthritis effects, but the mechanisms of these effects are not well understood. The objective of this... -
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- Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity
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Oh J, Yi S, Gu N, Shin D, Yu KS, Yoon SH, Cho JY, Jang IJ
- KMID: 2422812
- Genomics Inform.
- 2018 Sep;16(3):52-58.
- doi: 10.5808/GI.2018.16.3.52
In this report, we present a case study of how pharmacogenomics and pharmacometabolomics can be useful to characterize safety and pharmacokinetic profiles in early phase new drug development clinical trials.... -
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- Advances in Systems Biology Approaches for Autoimmune Diseases
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Kim HY, Kim HR, Lee SH
- KMID: 2168017
- Immune Netw.
- 2014 Apr;14(2):73-80.
- doi: 10.4110/in.2014.14.2.73
Because autoimmune diseases (AIDs) result from a complex combination of genetic and epigenetic factors, as well as an altered immune response to endogenous or exogenous antigens, systems biology approaches have... -
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- Urine metabolomic analysis to detect metabolites associated with the development of contrast induced nephropathy
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Diercks DB, Owen KP, Kline JA, Sutter ME
- KMID: 2367488
- Clin Exp Emerg Med.
- 2016 Dec;3(4):204-212.
- doi: 10.15441/ceem.15.110
OBJECTIVE: Contrast induced nephropathy (CIN) is a result of injury to the proximal tubules. The incidence of CIN is around 11% for imaging done in the acute care setting. We... -
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- Screening newborns for metabolic disorders based on targeted metabolomics using tandem mass spectrometry
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Yoon HR
- KMID: 2150386
- Ann Pediatr Endocrinol Metab.
- 2015 Sep;20(3):119-124.
- doi: 10.6065/apem.2015.20.3.119
The main purpose of newborn screening is to diagnose genetic, metabolic, and other inherited disorders, at their earliest to start treatment before the clinical manifestations become evident. Understanding and tracing... -
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- Gene-metabolite network analysis in different nonalcoholic fatty liver disease phenotypes
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Liu XL, Ming YN, Zhang JY, Chen XY, Zeng MD, Mao YM
- KMID: 2367529
- Exp Mol Med.
- 2017 Jan;49(1):e283.
- doi: 10.1038/emm.2016.123
We sought to identify common key regulators and build a gene-metabolite network in different nonalcoholic fatty liver disease (NAFLD) phenotypes. We used a high-fat diet (HFD), a methionine-choline-deficient diet (MCDD)... -
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- Wolves Trapped in the NETs–The Pathogenesis of Lupus Nephritis
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Kim Y, Shim SC
- KMID: 2408926
- J Rheum Dis.
- 2018 Apr;25(2):81-99.
- doi: 10.4078/jrd.2018.25.2.81
Systemic lupus erythematous (SLE) is a systemic autoimmune disease with multi-organ inflammation caused by the production of pathogenic autoantibodies and immune complexes reflecting a global loss of tolerance. Lupus nephritis... -
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- Integrative Omics Reveals Metabolic and Transcriptomic Alteration of Nonalcoholic Fatty Liver Disease in Catalase Knockout Mice
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Na J, Choi SA, Khan A, Huh JY, Piao L, Hwang I, Ha H, Park YH
- KMID: 2442004
- Biomol Ther.
- 2019 Feb;27(2):134-144.
- doi: 10.4062/biomolther.2018.175
The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased with the incidence of obesity; however, the underlying mechanisms are unknown. In this study, high-resolution metabolomics (HRM) along with transcriptomics... -
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- Advances in urinary biomarker discovery in urological research
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Kim J, Kim WT, Kim WJ
- KMID: 2469122
- Investig Clin Urol.
- 2020 Feb;61(Suppl 1):S8-S22.
- doi: 10.4111/icu.2020.61.S1.S8
A disease-specific biomarker (or biomarkers) is a characteristic reflecting a pathological condition in human body, which can be used as a diagnostic or prognostic tool for the clinical management. A... -
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