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Anticancer Effect of Magnolia officinalis' Extract on N-butyl-N-(4-hydroxybutyl) Nitrosamine Induced Bladder Cancer in Mice

Lee SC, Jung P, Kim YJ, Yun SJ, Lee SC, Kim WJ

  • KMID: 2311944
  • Korean J Urol.
  • 2008 Aug;49(8):682-687.
PURPOSE: Magnolia officinalis has been used in traditional Chinese medicine to treat a variety of diseases. The main constituents of Magnolia officinalis are honokiol and magnolol, which have a variety...
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Neolignan Derivatives from the Flower of Magnolia biondii Pamp. and their Effects on IL-2 expression in T-cells

Nguyen TT, Nguyen TT, Lee HS, Jun CD, Min BS, Kim JA

The isolation of the MeOH extract from the flower bud of Magnolia biondii Pamp. using various column chromatographies and HPLC led to eleven neoglignan derivatives (1 - 11). Their structures...
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Tissue regenerative activity of Magnolia and Zizyphi fructus extract mixtures

Lee YM, Ku Y, Bae KH, Chung CP

The purpose of this study was to perform on the biological activity of Magnolia and Zizyphi fructus extract mixtures on the wound healing of defected rat calvaria. For the determination...
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Comparative effects of aqueous single-phase and oil-water two-phase mouthrinses containing bamboo salt, magnolia bark and Centella asiatica extracts on reducing gingivitis: a randomized clinical trial

Choi S, Paik DI, Jin BH

OBJECTIVES: The aim of this study was to assess the antiplaque and antigingivitis effectiveness of aqueous single-phase and oil-water two-phase mouthrinses, containing bamboo salt, magnolia bark, and Centella asiatica extracts,...
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Magnoliae Cortex and maize modulate Porphyromonas gingivalis-induced inflammatory reactions

Kim JY, Kim KH, Kwag EH, Seol YJ, Lee YM, Ku Y, Rhyu IC

PURPOSE: The aim of this study was to evaluate the capacity of single and combined applications of the bark of the stems and roots of Magnolia officinalis Rehd. et Wils....
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Protective Effect of Magnolol Against Ceramide-induced Apoptosis in SK-N-SH cells

Lee DY, Kim SS, Kim KY, Lee WB

  • KMID: 1917151
  • Korean J Phys Anthropol.
  • 2003 Jun;16(2):119-127.
Magnolol, isolated from the stem bark of Magnolia officnalis, is typical Oriental herbs. It has been known to have many biological activities such as anti-platelet aggregation, hydroxyl radical scavenging, Ca2+...
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Effects of Magnoliae Cortex and Zizyphi Fructus Extract Mixtures on the Progression of Experimental Periodontitis in Beagle Dogs

Shin SY, Lee YM, Ku Y, Rhyu IC, Han SB, Choi SM, Bae KH, Chung CP

No abstract available.
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Inhibition of p65 Nuclear Translocation by KIOM-79

Kim JS, Jang DS, Jeon YJ, You HJ, Park KH, Ming J, Moon HY, Yoon SP, Chang IY

  • KMID: 1937821
  • Korean J Anat.
  • 2006 Apr;39(2):103-110.
We demonstrate that KIOM-79, combined extracts isolated from Magnolia officinalis, Pueraria lobata, Glycyrrhiza uralensis, and Euphorbia pekinensis, inhibits LPS-induced expression of iNOS gene in RAW 264.7 cells. Treatment of RAW...
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The Effect of Ethanolic Extracts Mixture from Magnoliae cortex and Carthami semen on the Progression of Experimental Periodontitis in Beagle Dogs

Seol YJ, Bae KH, Lee YM, Ku Y, Rhyu IC, Han SB, Bae KH, Choi SM, Chung CP

No abstract available.
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4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling

Kim SC, Kang JI, Hyun JW, Kang JH, Koh YS, Kim YH, Kim KH, Ko JH, Yoo ES, Kang HK

4-O-methylhonokiol, a neolignan compound from Magnolia Officinalis, has been reported to have various biological activities including hair growth promoting effect. However, although transforming growth factor-β (TGF-β) signal pathway has an...
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Magnolol Inhibits LPS-induced NF-kappaB/Rel Activation by Blocking p38 Kinase in Murine Macrophages

Li MH, Kothandan , Cho SJ, Huong PT, Nan YH, Lee KY, Shin SY, Yea SS, Jeon YJ

This study demonstrates the ability of magnolol, a hydroxylated biphenyl compound isolated from Magnolia officinalis, to inhibit LPS-induced expression of iNOS gene and activation of NF-kappaB/Rel in RAW 264.7 cells....
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Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity

Hu J, Chen LJ, Liu L, Chen X, Chen PL, Yang G, Hou WL, Tang MH, Zhang F, Wang XH, Zhao X, Wei YQ

Honokiol is an active compound purified from magnolia that has been shown to induce cell differentiation, apoptosis, and anti-angiogenesis effects, as well as an enhancement in tumor growth delay in...
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Honokiol ameliorates endothelial dysfunction through suppression of PTX3 expression, a key mediator of IKK/IkappaB/NF-kappaB, in atherosclerotic cell model

Qiu L, Xu R, Wang S, Li S, Sheng H, Wu J, Qu Y

Pentraxin 3 (PTX3) was identified as a marker of the inflammatory response and overexpressed in various tissues and cells related to cardiovascular disease. Honokiol, an active component isolated from the...
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Study on the antimicrobial activities of herbal extracts against Helicobacter pylori

Lee HA, Kim O

  • KMID: 1991780
  • Korean J Vet Res.
  • 2013 Jun;53(2):117-123.
Infection with Helicobacter (H.) pylori is strongly associated with duodenal and gastric ulcers. Substantial epidemiological data has revealed that high rates of H. pylori infection might be related to high...
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The effects of Magnoliae cortex and Zea Mays L. extract mixtures on experimentally induced periodontitis of beagle dog

Kim TI, Chung CP, Ku Y

It has been reported that Magnoliae cortex extract has antibacterial and antimicrobial activity against pathogenic microbes and Zea Mays L. extract is effective for improving gingival tissue health. The purpose...
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Antimicorbial effect of Zea Mays L. and Magnoliae cortex extract mixtures on periodontal pathogen and effect on human gingival fibroblast cellular activity

Kim TI, Choi EJ, Chung CP, Han SB, Ku Y

Zea Mays L. has been known to be effective for improving tissue health and Magnoliae cortex to have effective antibacterial and antimicrobial activity against pathogenic microbes. The purpose of this...
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Screening of Anti-HIV-1 Activity of Natural Product by MTT Assay

Lee JS, Nam JG, Kang C, Lee HR, Lee YJ, Shin YO

  • KMID: 2204569
  • J Korean Soc Virol.
  • 1997 Mar;27(1):87-95.
Methanol and/or boiling water extraction of 201 natural products and subsequent MTT assay using MT-4 cell line was carried out to screen the anti-HIV-1 activity. Among 97 methanol extracts, 7...
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Translocation of Phospho-ser 15-p53 in Eugenol-induced Apoptosis of in vitro Cultured Cancer Cells

Kim IR, Kim DJ, Lee BG, Jo JB, Kim GC, Kwak HH, Choi WC, Park BS

  • KMID: 2283415
  • Korean J Phys Anthropol.
  • 2007 Sep;20(3):245-255.
Eugenol (4-allyl-2-methoxyphenol), a major ingredient of herbs such as clove and Magnoliae Flos, is known to induce apoptosis in mast cells via p53 pathway. This study was undertaken to examine...
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The effect of zea Mays L. and Magnoliae cortex extracts mixture on the rat calvarial defects ; in vivo study of bone regenerative activity

Kim TI, Rhyu IC, Ku Y, Lee YM, Chung CP

I. PURPOSE OF STUDY: Zea Mays L. has been known to be effective for improving periodontal health and Magnoliae cortex to have effective antibacterial and antimicrobial activity against periodontal pathogens....
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Effects of Add-On Therapy with NDC-052, an Extract from Magnoliae Flos, in Adult Asthmatic Patients Receiving Inhaled Corticosteroids

Park CS, Kim TB, Lee JY, Park JY, Lee YC, Jeong SS, Lee YD, Cho YS, Moon HB

BACKGROUND/AIMS: There is a need for new anti-asthmatic medications with fewer side effects. NDC-052, an extract of the medicinal herb Magnoliae flos, which has a long history of clinical use,...
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