Korean J Vet Res.  2013 Jun;53(2):117-123.

Study on the antimicrobial activities of herbal extracts against Helicobacter pylori

Affiliations
  • 1Korean Medicine-Based Herbal Drug Research Group, Korea Institute of Oriental Medicine, Daejeon 305-811, Korea.
  • 2Center for Animal Resources Development, Wonkwang University, Iksan 570-749, Korea. kimoj@wku.ac.kr

Abstract

Infection with Helicobacter (H.) pylori is strongly associated with duodenal and gastric ulcers. Substantial epidemiological data has revealed that high rates of H. pylori infection might be related to high rates of gastric cancer. In this study, a medicinal herbal extracts were examined and screened for anti-H. pylori activity. Seventy percent ethanol was used for herbal extraction. For anti-H. pylori activity study, the inhibitory zone tests with 74 herbal compounds were conducted. As the results, thirteen compounds including Cinnamomi Cortex, Magnoliae Cortex and Meliae Fructus were revealed strong anti-H. pylori activities.

Keyword

antibacterial activity; anti-helicobacter; Helicobacter pylori; herb; in vitro

MeSH Terms

Drugs, Chinese Herbal
Ethanol
Helicobacter
Helicobacter pylori
Magnolia
Melia
Plants, Medicinal
Stomach Neoplasms
Stomach Ulcer
Drugs, Chinese Herbal
Ethanol
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