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Significance of Differential Characteristics in Infantile Kawasaki Disease

Kwak JH, Lee J, Ha KS

BACKGROUND AND OBJECTIVES: Immunological variability in Kawasaki disease (KD) shows age-specific differences; however, specific differences in laboratory values have not been compared between infants and non-infants with KD. We compared...
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The Effect of Mycophenolate Mofetil on Non-Renal Manifestations in Systemic Lupus Erythematosus: Results from Korean Lupus Network Registry

Jung UH, Kwak SG, Choe JY, Lee SS, Kim SK

BACKGROUND: The objective of this study was to identify the effects of mycophenolate mofetil (MMF) on non-renal manifestations in systemic lupus erythematosus (SLE). METHODS: The study population comprised 439 SLE patients...
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The autophagy Protein Atg5 Plays a Crucial Role in the Maintenance and Reconstitution Ability of Hematopoietic Stem Cells

Jung HE, Shim YR, Oh JE, Oh DS, Lee HK

Hematopoietic stem cells (HSCs) in bone marrow are pluripotent cells that can constitute the hematopoiesis system through self-renewal and differentiation into immune cells and red blood cells. To ensure a...
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CRISPR/Cas9-mediated knockout of Rag-2 causes systemic lymphopenia with hypoplastic lymphoid organs in FVB mice

Kim JI, Park JS, Kim H, Ryu SK, Kwak J, Kwon E, Yun JW, Nam KT, Lee HW, Kang BC

Recombination activating gene-2 (RAG-2) plays a crucial role in the development of lymphocytes by mediating recombination of T cell receptors and immunoglobulins, and loss of RAG-2 causes severe combined immunodeficiency...
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The Prognostic Value of Treatment-Related Lymphopenia in Nasopharyngeal Carcinoma Patients

Liu LT, Chen QY, Tang LQ, Guo SS, Guo L, Mo HY, Chen MY, Zhao C, Guo X, Qian CN, Zeng MS, Bei JX, Tan J, Chen S, Hong MH, Shao JY, Sun Y, Ma J, Mai HQ

PURPOSE: This study was conducted to evaluate the prognostic value of treatment-related lymphopenia in patients with nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS: A total of 413 consecutive stage II-IVb NPC patients...
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Lower Respiratory Tract Diseases Caused by Common Respiratory Viruses among Stem Cell Transplantation Recipients: A Single Center Experience in Korea

Hong KW, Choi SM, Lee DG, Cho SY, Lee HJ, Choi JK, Kim SH, Park SH, Choi JH, Yoo JH, Lee JW

PURPOSE: To describe the incidence, clinical courses, and risk factors for mortality of lower respiratory tract diseases (LRDs) caused by common respiratory viruses (CRVs) in stem cell transplantation (SCT) recipients. MATERIALS...
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Pretreatment Lymphopenia, Poor Performance Status, and Early Courses of Therapy Are Risk Factors for Severe Bacterial Infection in Patients with Multiple Myeloma during Treatment with Bortezomib-based Regimens

Hyun SY, Han SH, Kim SJ, Jang JE, Kim Y, Cho H, Lee JY, Cheong JW, Min YH, Song JW, Kim JS

The aim of this study was to identify the risk factors associated with severe bacterial infection (SBI) in multiple myeloma (MM) patients during treatment with bortezomib-based regimens. A total of...
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Lymphopenia and Elevated Blood C-Reactive Protein Levels at Four Days Postoperatively Are Useful Markers for Early Detection of Surgical Site Infection Following Posterior Lumbar Instrumentation Surgery

Iwata E, Shigematsu H, Koizumi M, Nakajima H, Okuda A, Morimoto Y, Masuda K, Tanaka Y

STUDY DESIGN: Case-control study. PURPOSE: To identify the characteristics of candidate indexes for early detection of surgical site infection (SSI). OVERVIEW OF LITERATURE: SSI is a serious complication of spinal instrumentation surgery....
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Lymphopenia at 4 Days Postoperatively Is the Most Significant Laboratory Marker for Early Detection of Surgical Site Infection Following Posterior Lumbar Instrumentation Surgery

Iwata E, Shigematsu H, Okuda A, Morimoto Y, Masuda K, Nakajima H, Koizumi M, Tanaka Y

STUDY DESIGN: Case control study. PURPOSE: To identify the most significant laboratory marker for early detection of surgical site infection (SSI) using multiple logistic regression analysis. OVERVIEW OF LITERATURE: SSI is a...
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Systemic Lupus Erythematosus Presenting as Monocular Elevation Deficiency

Kim SW, Kim YH, Chung SA

PURPOSE: To report a case of monocular elevation deficiency as the presenting manifestation of systemic lupus erythematosus (SLE). CASE SUMMARY: A 23-year-old, otherwise healthy female presented with a 3-day history of...
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The Correlation between NK Cell and Liver Function in Patients with Primary Hepatocellular Carcinoma

Sha WH, Zeng XH, Min L

  • KMID: 1774564
  • Gut Liver.
  • 2014 May;8(3):298-305.
BACKGROUND/AIMS: This study aimed to detect the expression of natural killer (NK) cell receptor natural killer group 2D (NKG2D) in the peripheral blood of patients with primary hepatocellular carcinoma and...
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CD163 and c-Met expression in the lymph node and the correlations between elevated levels of serum free light chain and the different clinicopathological parameters of advanced classical Hodgkin's lymphoma

Bedewy M, El-Maghraby S, Bedewy A

BACKGROUND: Advances in the understanding of Hodgkin's lymphoma (HL) show various functions of infiltrating immune cells and cytokines in relation to clinical outcomes. The expression of CD163 and c-Met has...
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Indeterminate T-SPOT.TB Test Results in Patients with Suspected Extrapulmonary Tuberculosis in Routine Clinical Practice

Lee YM, Kim SM, Park SJ, Park KH, Lee SO, Choi SH, Kim YS, Woo JH, Kim SH

  • KMID: 2391839
  • Infect Chemother.
  • 2013 Mar;45(1):44-50.
BACKGROUND: The two interferon-gamma release assays such as QuantiFERON-TB Gold / In-Tube (QFT-TB) and T-SPOT.TB-are useful tools for the rapid diagnosis of tuberculosis (TB) but can yield indeterminate test results...
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Classification of acute clinical mastitis on the base of vital signs and complete blood count test in dairy cows

Hur TY, Kang SJ, Jung YH, Lee HJ, Ki KS, Choe CY, Suh GH

  • KMID: 1991788
  • Korean J Vet Res.
  • 2013 Mar;53(1):19-23.
This study was carried out to evaluate the diagnosis of acute clinical mastitis (ACM) which was based on the vital signs and complete blood count (CBC) tests in dairy cows....
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Motor Axonal Neuropathy Associated With Idiopathic CD4+ T-Lymphocytopenia

Yi TI, Kim BR, Han IS, Kim BK

Idiopathic CD4+ T-lymphocytopenia is a rare immune disorder characterized by an unexplained deficit of CD4+ T cells and results in various opportunistic infections. Herein, we report a case of new...
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Respiratory Viral Infections after Hematopoietic Stem Cell Transplantation in Children

Choi JH, Choi EH, Kang HJ, Park KD, Park SS, Shin HY, Lee HJ, Ahn HS

This study was performed to characterize respiratory viral infections in pediatric patients undergoing hematopoietic stem cell transplantation (HSCT). Study samples included 402 respiratory specimens obtained from 358 clinical episodes that...
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A Case of Primary Intestinal Lymphangiectasia Diagnosed by Double Balloon Enteroscopy

Lee JM, Kim JB, Bak SW, Lee BK, Lee NH, Seo YH

Primary intestinal lymphangiectasia is a congenital lymphatic disorder characterized by dilated intestinal lacteals resulting in lymph leakage into the small bowel lumen and responsible for protein losing enteropathy. As a...
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Factors Associated with Indeterminate and False Negative Results of QuantiFERON-TB Gold In-Tube Test in Active Tuberculosis

Cho K, Cho E, Kwon S, Im S, Sohn I, Song S, Kim H, Kim S

  • KMID: 2319815
  • Tuberc Respir Dis.
  • 2012 May;72(5):416-425.
BACKGROUND: The sensitivities and specificities of interferon-gamma release assays (IGRAs) vary among different population studies, and the data on the routine use of IGRAs are limited. The aim of this...
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Characteristics of Hospitalized Children with 2009 Pandemic Influenza A (H1N1): A Multicenter Study in Korea

Ko JH, Kim JH, Kang JH, Kim JH, Eun BW, Kim KH, Hong JY, Oh SH

The majority of Korean patients with pandemic influenza A (H1N1) during the 2009 epidemic were under 20 yr of age. The limited data on the clinical characteristics of these children...
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Multiple Opportunistic Infections and Primary Central Nervous System Lymphoma in a Patient with Idiopathic CD4+ T-lymphocytopenia

Song JS, Choe PG, Song KH, Park KU, Park WB, Park SW, Kim NJ, Oh MD, Kim HB

We describe a case of idiopathic CD4+ T-lymphocytopenia (ICL) in a 59-year-old patient who presented with various opportunistic infections. The patient was diagnosed with disseminated Mycobacterium avium infection, cytomegalovirus colitis...
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