Chonnam Med J.  2001 Sep;37(3):305-309.

A Case of Pneumocystis Carinii Pneumonia in a Patient with Felty's Syndome

Affiliations
  • 1Department of Internal Medicine, Pusan National University, Pusan, Korea.

Abstract

Felty's syndrome (FS), which comprises rheumatoid arthritis (RA), neutropenia, and often spleno-megaly, occurs in 1% of RA patients. Although neutropenia is the most prominent feature, other hematologic abnormalities including anemia, lymphopenia and thrombocytopenia, have been described to various extension. Infection is the major cause of death in FS. Most of infections are caused by bacteria. Opportunistic infections are rare, because the incidence of infection is, in general, related to the degree of neutropenia. Peumocystis carinii pneumonia (PCP) is an opportunistic infection in immune compromised patients with acquired immune deficiency syndrome (AIDS), hematologic malignant disorders, organ transplantation, solid tumor and inflammatory rheumatic disease. We experienced PCP in a patient with FS who had neutropenia and lymphopenia.

Keyword

Felty's syndrome; Pneumocystis carinii pneumonia

MeSH Terms

Acquired Immunodeficiency Syndrome
Anemia
Arthritis, Rheumatoid
Bacteria
Cause of Death
Felty Syndrome
Humans
Incidence
Lymphopenia
Neutropenia
Opportunistic Infections
Organ Transplantation
Pneumocystis carinii*
Pneumocystis*
Pneumonia
Pneumonia, Pneumocystis*
Rheumatic Diseases
Thrombocytopenia
Transplants
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