- Luteolin Induces the Differentiation of Osteoblasts
-
Ko SY
- KMID: 1457182
- Int J Oral Biol.
- 2010 Sep;35(3):99-106.
Luteolin is a flavonoid that exists in a glycosylated form in celery and green pepper. Flavonoids possess antioxidant and anti-inflammatory properties and can reduce the expression of key inflammatory molecules... -
- CITED
-
- Close
- SHARE
-
- Close
- Luteolin and luteolin-7-O-glucoside protect against acute liver injury through regulation of inflammatory mediators and antioxidative enzymes in GalN/LPS-induced hepatitic ICR mice
-
Park CM, Song YS
- KMID: 2464126
- Nutr Res Pract.
- 2019 Dec;13(6):473-479.
- doi: 10.4162/nrp.2019.13.6.473
BACKGROUND/OBJECTIVES: Anti-inflammatory and antioxidative activities of luteolin and luteolin-7-O-glucoside were compared in galactosamine (GalN)/lipopolysaccharide (LPS)-induced hepatitic ICR mice. MATERIALS/METHODS: Male ICR mice (6 weeks old) were divided into 4 groups: normal... -
- CITED
-
- Close
- SHARE
-
- Close
- Luteolin and luteolin-7-O-glucoside inhibit lipopolysaccharide-induced inflammatory responses through modulation of NF-kappaB/AP-1/PI3K-Akt signaling cascades in RAW 264.7 cells
-
Park CM, Song YS
- KMID: 2313690
- Nutr Res Pract.
- 2013 Dec;7(6):423-429.
Luteolin is a flavonoid found in abundance in celery, green pepper, and dandelions. Previous studies have shown that luteolin is an anti-inflammatory and anti-oxidative agent. In this study, the anti-inflammatory... -
- CITED
-
- Close
- SHARE
-
- Close
- Inhibitory Effect of Luteolin Liposome Solution by Animal Model for Atopic Dermatitis in NC/Nga Mice
-
Choi MJ, Lee YM, Jin BS, Kim BH
- KMID: 1458939
- Lab Anim Res.
- 2010 Mar;26(1):47-53.
- doi: 10.5625/lar.2010.26.1.47
Atopic dermatitis is a common chronic inflammatory skin disease, associated with marked inflammatory cells (of mast cells and eosinophils) and severe itching, which leads to clinical problems in the pediatric... -
- CITED
-
- Close
- SHARE
-
- Close
- Sleep Promoting Effect of Luteolin in Mice via Adenosine A1 and A2A Receptors
-
Kim TH, Custodio R, Cheong JH, Kim HJ, Jung YS
- KMID: 2462886
- Biomol Ther.
- 2019 Nov;27(6):584-590.
- doi: 10.4062/biomolther.2019.149
Luteolin, a widespread flavonoid, has been known to have neuroprotective activity against various neurologic diseases such as epilepsy, and Alzheimer’s disease. However, little information is available regarding the hypnotic effect... -
- CITED
-
- Close
- SHARE
-
- Close
- Luteolin 5-O-glucoside from Korean Milk Thistle, Cirsium maackii, Exhibits Anti-Inflammatory Activity via Activation of the Nrf2/HO-1 Pathway
-
Jung HA, Roy A, Abdul QA, Kim HR, Park HJ, Choi JS
- KMID: 2393799
- Nat Prod Sci.
- 2017 Sep;23(3):183-191.
- doi: 10.20307/nps.2017.23.3.183
Luteolin 5-O-glucoside is the major flavonoid from Korean thistle, Cirsium maackii. We previously reported the anti-inflammatory activities of luteolin 5-O-glucoside in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. In this study, we... -
- CITED
-
- Close
- SHARE
-
- Close
- Luteolin Inhibits the Activity, Secretion and Gene Expression of MMP-3 in Cultured Articular Chondrocytes and Production of MMP-3 in the Rat Knee
-
Kang BJ, Ryu J, Lee CJ, Hwang SC
- KMID: 2170642
- Biomol Ther.
- 2014 May;22(3):239-245.
We investigated whether luteolin affects the gene expression, secretion and activity of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as production of MMP-3 in the rat... -
- CITED
-
- Close
- SHARE
-
- Close
- Quantitative Determination of Five Phenolic Peroxynitrite-scavengers in Nine Korean Native Compositae herbs
-
Nugroho A, Lim SC, Karki S, Choi JS, Park HJ
- KMID: 2312890
- Nat Prod Sci.
- 2015 Sep;21(3):155-161.
- doi: 10.0000/nps.2015.21.3.155
Peroxynitrite (ONOO-)-scavenging activities of nine Compositae herbs consisting of three Ixeris, two Youngia, two Cirsium and one of each Lactuca and Taraxacum species were evaluated. The contents of their ONOO-... -
- CITED
-
- Close
- SHARE
-
- Close
- Inhibitory Effect of Flavonoid Luteolin on 6-Hydroxydopamine Cytotoxicity via Suppression of Apoptosis-Related Protein Activation
-
Lee SW, Kang JH, Han JH, Kim DE, Lee CS
- KMID: 2191521
- J Korean Neurol Assoc.
- 2012 Nov;30(4):284-292.
BACKGROUND: Flavonoid luteolin has been shown to exhibit cell protective effect. However, it is still uncertain whether the effect of luteolin on cellular toxicity of the parkinsonian toxin 6-hydroxydopamine is... -
- CITED
-
- Close
- SHARE
-
- Close
- Luteolin Induces Apoptosis via Mitochondrial Pathway and Inhibits Invasion and Migration of Oral Squamous Cell Carcinoma by Suppressing Epithelial-Mesenchymal Transition Induced Transcription Factors
-
Park BS, Kil JJ, Kang HM, Yu SB, Park DB, Park JA, Kim IR
- KMID: 2437357
- Int J Oral Biol.
- 2018 Jun;43(2):69-76.
- doi: 10.11620/IJOB.2018.43.2.069
Oral squamous cell carcinoma (OSCC) is the most common type of oral malignancy. Numerous therapies have been proposed for its cure. Research is continually being conducted to develop new forms... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of the Flavonoid Luteolin for Dextran Sodium Sulfate-induced Colitis in NF-kappa BEGFP Transgenic Mice
-
Jang BI
- KMID: 2320162
- Yeungnam Univ J Med.
- 2006 Jun;23(1):26-35.
BACKGROUND: Luteolin, a flavone found in various Chinese herbal medicines is known to possess anti-inflammatory properties through its ability to inhibit various proinflammatory signaling pathways including NF-kappa B and p38... -
- CITED
-
- Close
- SHARE
-
- Close
- Phytochemical Analysis of the Phenolic Fat-Suppressing Substances in the Leaves of Lactuca raddeana in 3T3-L1 Adipocytes
-
Nugroho A, Choi JS, An HJ, Park HJ
- KMID: 2409598
- Nat Prod Sci.
- 2015 Mar;21(1):42-48.
- doi: 10.0000/nps.2015.21.1.42
Lactuca raddeana (Compositae) is used to treat obesity and complications due to diabetes. The five phenolic compounds including chlorogenic acid, chicoric acid, luteolin 7-O-glucoside, luteolin 7-O-glucuronide, luteolin were qualitatively identified... -
- CITED
-
- Close
- SHARE
-
- Close
- Luteolin and fisetin suppress oxidative stress by modulating sirtuins and forkhead box O3a expression under in vitro diabetic conditions
-
Kim A, Lee W, Yun JM
- KMID: 2390136
- Nutr Res Pract.
- 2017 Oct;11(5):430-434.
- doi: 10.4162/nrp.2017.11.5.430
BACKGROUND/OBJECTIVE: Chronic hyperglycemia induces oxidative stress via accumulation of reactive oxygen species (ROS) and contributes to diabetic complications. Hyperglycemia induces mitochondrial superoxide anion production through the increased activity of nicotinamide... -
- CITED
-
- Close
- SHARE
-
- Close
- Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway
-
Masraksa W, Tanasawet , Hutamekalin P, Wongtawatchai T, Sukketsiri W
- KMID: 2471880
- Nutr Res Pract.
- 2020 Apr;14(2):127-133.
- doi: 10.4162/nrp.2020.14.2.127
BACKGROUND/OBJECTIVES: Non-small cell lung cancer is mostly recognized among other types of lung cancer with a poor prognosis by cause of chemotherapeutic resistance and increased metastasis. Luteolin has been found... -
- CITED
-
- Close
- SHARE
-
- Close
- The effects of Angelica keiskei Koidz on the expression of antioxidant enzymes related to lipid profiles in rats fed a high fat diet
-
Kim E, Choi J, Yeo I
- KMID: 2313569
- Nutr Res Pract.
- 2012 Feb;6(1):9-15.
This study was performed to examine the feeding effects of Angelica keiskei Koidz (AK) and its processed products on serum, liver, and body fat content and the expression of antioxidant... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of luteolin on chemical induced colon carcinogenesis in high fat diet-fed obese mouse
-
Park JE, Kim E
- KMID: 2410321
- J Nutr Health.
- 2018 Feb;51(1):14-22.
- doi: 10.4163/jnh.2018.51.1.14
PURPOSE: Colorectal cancer, which is one of the most commonly diagnosed cancers in developing and developed countries, is highly associated with obesity. The association is largely attributed to changes to... -
- CITED
-
- Close
- SHARE
-
- Close
- Isolation and Quantitative Analysis of BACE1 Inhibitory Compounds from Cirsium maackii Flower
-
Bhatarrai , Seong SH, Jung HA, Choi JS
- KMID: 2468066
- Nat Prod Sci.
- 2019 Dec;25(4):326-333.
- doi: 10.20307/nps.2019.25.4.326
The purpose of our study was to evaluate anti-AD potential of Cirsium maackii flowers. MeOH extract, CH2Cl2, EtOAc, and n-BuOH fraction of this flower notably inhibited BACE1 (ICâ‚…â‚€ = 76.47... -
- CITED
-
- Close
- SHARE
-
- Close
- Phytochemical Constituents of Capsella bursa-pastoris and Their Anti-inflammatory Activity
-
Cha JM, Kim DH, Lee TH, Subedi L, Kim SY, Lee KR
- KMID: 2416075
- Nat Prod Sci.
- 2018 Jun;24(2):132-138.
- doi: 10.20307/nps.2018.24.2.132
Phytochemical investigation of 80% MeOH extract of the aerial parts of Capsella bursa-pastoris yielded fourteen compounds (1 – 14). The structures of the compounds were elucidated by spectroscopic methods to... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Flavonoid Compounds on beta-amyloid-peptide-induced Neuronal Death in Cultured Mouse Cortical Neurons
-
Choi SM, Kim BC, Cho YH, Choi KH, Chang J, Park MS, Kim MK, Cho KH, Kim JK
- KMID: 2172158
- Chonnam Med J.
- 2014 Aug;50(2):45-51.
- doi: 10.4068/cmj.2014.50.2.45
Excessive accumulation of beta-amyloid peptide (Abeta) is one of the major mechanisms responsible for neuronal death in Alzheimer's disease. Flavonoids, primarily antioxidants, are a group of polyphenolic compounds synthesized in... -
- CITED
-
- Close
- SHARE
-
- Close
- Phenolic Constituents and Their Anti-inflammatory Activity from Echinochloa utilis Grains
-
Nguyen DH, Zhao BT, Le DD, Kim KY, Kim YH, Yoon YH, Ko JY, Woo KS, Woo MH
- KMID: 2328881
- Nat Prod Sci.
- 2016 Jun;22(2):140-145.
- doi: 10.20307/nps.2016.22.2.140
Seven phenolic compounds including p-coumaric acid (1), 4-hydroxybenzoic acid (2), 4-hydroxybenzaldehyde (3), vanillic acid (4), luteolin (5), acacetin (6), and tricin (7), were isolated from the methylene chloride and ethyl... -
- CITED
-
- Close
- SHARE
-
- Close
