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The Electron Microscopic study of the Synapses of the Locus Coeruleus in the Squirrel Monkey, Saimiri sciureus

Lee HL, Kim SH

This study provides a description of the normal morphology of the synapses of the locus coeruleus in the squirrel monkey, Saimiri sciureus, at the electron microscopic level. The animals were...
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Is this Red Spot the Blue Spot (locus ceruleus)?

Choe W, Lee Y, Lee M, Hwang KH

  • KMID: 1709321
  • Nucl Med Mol Imaging.
  • 2010 Jun;44(2):157-158.
The authors report brain images of 18F-FDG-PET in a case of schizophrenia. The images showed strikingly increased bilateral uptake in the locus ceruleus. The locus ceruleus is called the blue...
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Brain Mechanisms Generating REM Sleep

Sohn JW

  • KMID: 2317251
  • Sleep Med Psychophysiol.
  • 1995 Dec;2(2):133-137.
The author reviews current knowledge about what REM sleep is and where and how it is generated. REM sleep is the state in which our most vivid dreams occur. REM...
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Analysis of Electrophysiological Change in the Rat LC Nucleus after Salicylic Acid Treatment

Kim SC, Kim SB, Park SY, Jun BH

  • KMID: 2276565
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Feb;49(2):148-152.
BACKGROUND AND OBJECTIVES: The precise mechanism of salicylic acid induced tinnitus has not been clearly identified as yet in spite of wide range of studies undertaken. We looked for the...
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Locus Ceruleus Terminals in the Fundus Striati[Nucleus accumbens septi] of the Cat : Electron Microscopic Study

Kim TS, Chun MH, Jung JW

  • KMID: 2224621
  • Korean J Anat.
  • 1997 Aug;30(4):421-430.
Although the distribution of locus ceruleus terminals has been demonstrated in the fundus striati[nucleus accumbens septi] by light microscopy[Jones & Moore, 1977 ; Mason & Fibiger, 1979 ; Streit or...
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Neuroanatomy of Sleep-Wake Regulation and its Application to Pharmacotherapy

Kim HC

  • KMID: 2286720
  • Korean J Psychopharmacol.
  • 2007 May;18(3):133-142.
A current hypothesis of sleep-wake regulation proposes that the sleep process starts with the activation of sleep-promoting neurons located in the preoptic area of the anterior hypothalamus. This activation leads...
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Effects of Phenylephrine on the Excitability of Medial Vestibular Nuclear Neurons in Rats

Jeong HS, Huh HR, Jang MJ, Hong SH, Jang S, Park J, Lee SH, Kim JH, Park JS

  • KMID: 2285323
  • Korean J Physiol Pharmacol.
  • 2006 Jun;10(3):131-135.
Coeruleo-vestibular pathway which connects locus coeruleus and vestibular nuclei is noradrenergic. This study was designed to elucidate the effects of phenylephrine on the spontaneous activity of acutely isolated medial vestibular...
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C-fos Expression in Brain Stem of Rats after Salicylic Acid Treatment

Kim SC, Jun BH, Choi IS, Jung BJ, Kim DS

  • KMID: 2275882
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Mar;45(3):214-218.
BACKGROUND AND OBJECTIVES: Subjective tinnitus, a distracting internal noise, is experienced by humans. Tinnitus is evoked by salicylic acid treatment in rats as confirmed by Jastreboff in 1994 in an...
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Evaluation of recombinant adenovirus-mediated gene delivery for expression of tracer genes in catecholaminergic neurons

Kim ML, Han S, Lee SB, Kim JH, Ahn HK, Huh Y

Selective labeling of small populations of neurons of a given phenotype for conventional neuronal tracing is difficult because tracers can be taken up by all neurons at the injection site,...
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The effects of chronic lead exposure on norepinephrinergic neurons of the nucleus locus ceruleus of the rat

Lee WT, Yoon H, Lee DJ, Lee JE, Koo CH, Park KA

  • KMID: 2224553
  • Korean J Anat.
  • 2000 Aug;33(4):423-432.
The neurotoxic effects of inorganic lead, a common environmental toxic substance, include peripheral neuropathy in adults and encephalopathy in children. Behavioral changes including hyperactivity, short attention span, easy distractibility and...
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Effect of Berberine on Depression- and Anxiety-Like Behaviors and Activation of the Noradrenergic System Induced by Development of Morphine Dependence in Rats

Lee B, Sur B, Yeom M, Shim I, Lee H, Hahm DH

The purpose of this study was to evaluate whether berberine (BER) administration could attenuate depression- and anxiety-like behaviors and increase corticotrophin-releasing factor (CRF) and tyrosine hydroxylase (TH) expression following chronic...
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Behavioral and Histochemical Changes in MPTP-treated C57BL/6 Mice: A Model for Parkinson's Disease

Kim JW, Lee SK, Ha KM

  • KMID: 2138112
  • J Korean Neurol Assoc.
  • 1993 Jun;11(2):175-180.
The effects of 1-methyl-4-phenyl-1, 2. 3, 6-tetrahydropyridine (MPTP) on behavioral and histochemical changes were investigated in C57BL/6 mice. For immunocytochemis try, one group of mice received a dose of 2X30mg/kg...
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In Vivo Microdialysis Measures of Extracellular Norepinephrine in the Rat Amygdala during Sleep-wakefulness

Park SP

Norepinephrine (NE)-containing locus ceruleus (LC) has been known to participate in the regulation of the sleep-wake cycle according to the differential firing rate. The aim of this study was to...
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The Effect of MPTP in The Mouse Brain in Relation to Aging: Immunocytochemical Analysis

Kim JW, Lee SK, Ha KM

  • KMID: 2342392
  • J Korean Neurol Assoc.
  • 1994 Jun;12(2):183-187.
The effect of MPTP on catecholamine neurons in young (4-6 weeks) and aging (10-12 months) C57BL/6 mice was studied using immunocytochemical techniques. Both groups of mice received 4 repeated dosages...
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Effects of electrical stimulation of brainstem nuclei on dorsal horn neuron responses to mechanical stimuli in a rat model of neuropathic pain

Leem JW, Choi Y, Gwak YS, Nam TS, Paik KS

  • KMID: 2285168
  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):241-249.
The aim of the present study is to examine the brainstem sites where the electrical stimulation produces a suppression of dorsal horn neuron responses of neuropathic rats. An experimental neuropathy was induced by...
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Tracing Study on Neuroaxis of Medial Rectus Muscle in the Brain Stem of the White Rat

Lee HB, Suh SW, Yoo JM

  • KMID: 2123805
  • J Korean Ophthalmol Soc.
  • 1998 Dec;39(12):3053-3062.
To clarify neuronal connection of the medial rectus muscle at brain stem, Bartha strain of the psecudorabies virus(PRV-Ba) and cholera toxin-horeserdish peroxidase(CT-HRP) was injected into medial rectus muscle of the...
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Safe Sedation and Hypnosis using Dexmedetomidine for Minimally Invasive Spine Surgery in a Prone Position

Kim KH

Dexmedetomidine, an imidazoline compound, is a highly selective alpha2-adrenoceptor agonist with sympatholytic, sedative, amnestic, and analgesic properties. In order to minimize the patients' pain and anxiety during minimally invasive spine...
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Chronic Administration of Catechin Decreases Depression and Anxiety-Like Behaviors in a Rat Model Using Chronic Corticosterone Injections

Lee B, Sur B, Kwon S, Yeom M, Shim I, Lee H, Hahm DH

  • KMID: 2170678
  • Biomol Ther.
  • 2013 Jul;21(4):313-322.
Previous studies have demonstrated that repeated administration of the exogenous stress hormone corticosterone (CORT) induces dysregulation in the hypothalamic-pituitary-adrenal (HPA) axis and results in depression and anxiety. The current study...
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Neuroimmunological Activation of Afferent Auditory Neural Circuit in LPS-Induced Otitis Media

Jun BC, Kim HT, Song CE, Lee DH, Yeo SW

  • KMID: 1977287
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Oct;49(10):978-985.
BACKGROUND AND OBJECTIVES : The goal of this study was to identify the central modulation of the auditory pathway by peripheral inflammation and loud sound exposure, which is associated with...
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Immunocytochemical Studies of Calbindin D-28k and Parvalbumin-Containing GABAergic Neurons in the Midbrain of the Cat

Kim JJ, Jeong SB, Kim NH, Ahn GH, Chung YY, Moon JS, Chang IY, Kim HS

  • KMID: 2071859
  • Korean J Phys Anthropol.
  • 2000 Jun;13(2):201-211.
This study was carried out to investigate the morphology, distribution and co-localization of calbindin D-28k and parvalbumin-containing GABAergic cells in the midbrain of the cat. The results obtain by immunocytochemical...
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