- Mechanisms of Alzheimer's Disease Pathogenesis and Prevention: The Brain, Neural Pathology, N-methyl-D-aspartate Receptors, Tau Protein and Other Risk Factors
-
Kocahan S, DoÄŸan Z
- KMID: 2367656
- Clin Psychopharmacol Neurosci.
- 2017 Feb;15(1):1-8.
- doi: 10.9758/cpn.2017.15.1.1
The characteristic features of Alzheimer's disease (AD) are the appearance of extracellular amyloid-beta (Aβ) plaques and neurofibrillary tangles in the intracellular environment, neuronal death and the loss of synapses, all... -
- CITED
-
- Close
- SHARE
-
- Close
- Safe Sedation and Hypnosis using Dexmedetomidine for Minimally Invasive Spine Surgery in a Prone Position
-
Kim KH
- KMID: 1802496
- Korean J Pain.
- 2014 Oct;27(4):313-320.
- doi: 10.3344/kjp.2014.27.4.313
Dexmedetomidine, an imidazoline compound, is a highly selective alpha2-adrenoceptor agonist with sympatholytic, sedative, amnestic, and analgesic properties. In order to minimize the patients' pain and anxiety during minimally invasive spine... -
- CITED
-
- Close
- SHARE
-
- Close
- Alpha-Asarone, a Major Component of Acorus gramineus, Attenuates Corticosterone-Induced Anxiety-Like Behaviours via Modulating TrkB Signaling Process
-
Lee B, Sur B, Yeom M, Shim I, Lee H, Hahm DH
- KMID: 2285510
- Korean J Physiol Pharmacol.
- 2014 Jun;18(3):191-200.
- doi: 10.4196/kjpp.2014.18.3.191
We investigated the anxiolytic-like activity of alpha-asarone (AAS) from Acorus gramineus in an experimental rat model of anxiety induced by repeated administration of the exogenous stress hormone corticosterone (CORT). The... -
- CITED
-
- Close
- SHARE
-
- Close
- Chronic Administration of Catechin Decreases Depression and Anxiety-Like Behaviors in a Rat Model Using Chronic Corticosterone Injections
-
Lee B, Sur B, Kwon S, Yeom M, Shim I, Lee H, Hahm DH
- KMID: 2170678
- Biomol Ther.
- 2013 Jul;21(4):313-322.
Previous studies have demonstrated that repeated administration of the exogenous stress hormone corticosterone (CORT) induces dysregulation in the hypothalamic-pituitary-adrenal (HPA) axis and results in depression and anxiety. The current study... -
- CITED
-
- Close
- SHARE
-
- Close
- Alpha-Synuclein Expression in Patients with Parkinson's Disease: A Clinician's Perspective
-
Kim HJ
- KMID: 1427105
- Exp Neurobiol.
- 2013 Jun;22(2):77-83.
- doi: 10.5607/en.2013.22.2.77
Although physiological function of alpha-synuclein is not yet clearly understood, accumulating evidence strongly suggests it plays a crucial role in the pathogenesis of Parkinson disease. Pathologically, alpha-synuclein is a major... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Berberine on Depression- and Anxiety-Like Behaviors and Activation of the Noradrenergic System Induced by Development of Morphine Dependence in Rats
-
Lee B, Sur B, Yeom M, Shim I, Lee H, Hahm DH
- KMID: 2285445
- Korean J Physiol Pharmacol.
- 2012 Dec;16(6):379-386.
- doi: 10.4196/kjpp.2012.16.6.379
The purpose of this study was to evaluate whether berberine (BER) administration could attenuate depression- and anxiety-like behaviors and increase corticotrophin-releasing factor (CRF) and tyrosine hydroxylase (TH) expression following chronic... -
- CITED
-
- Close
- SHARE
-
- Close
- Dexmedetomidine sedation in ICU
-
Yu SB
- KMID: 2243817
- Korean J Anesthesiol.
- 2012 May;62(5):405-411.
- doi: 10.4097/kjae.2012.62.5.405
Dexmedetomidine (DEX), a highly selective alpha2-adrenergic receptor agonist, is the newest agent introduced for sedation in intensive care unit (ICU). The sedation strategy for critically ill patients has stressed light... -
- CITED
-
- Close
- SHARE
-
- Close
- Normal Sleep in Children and Adolescents
-
Nam SO
- KMID: 1442105
- J Korean Child Neurol Soc.
- 2011 Aug;19(2):67-75.
Sleep is not just a rest for brain activity during daytime, but also has a vital function for memory consolidation after learning as well as restoration of both body and... -
- CITED
-
- Close
- SHARE
-
- Close
- Evaluation of recombinant adenovirus-mediated gene delivery for expression of tracer genes in catecholaminergic neurons
-
Kim ML, Han S, Lee SB, Kim JH, Ahn HK, Huh Y
- KMID: 2168889
- Anat Cell Biol.
- 2010 Jun;43(2):157-164.
- doi: 10.5115/acb.2010.43.2.157
Selective labeling of small populations of neurons of a given phenotype for conventional neuronal tracing is difficult because tracers can be taken up by all neurons at the injection site,... -
- CITED
-
- Close
- SHARE
-
- Close
- Is this Red Spot the Blue Spot (locus ceruleus)?
-
Choe W, Lee Y, Lee M, Hwang KH
- KMID: 1709321
- Nucl Med Mol Imaging.
- 2010 Jun;44(2):157-158.
The authors report brain images of 18F-FDG-PET in a case of schizophrenia. The images showed strikingly increased bilateral uptake in the locus ceruleus. The locus ceruleus is called the blue... -
- CITED
-
- Close
- SHARE
-
- Close
- Neuroanatomy of Sleep-Wake Regulation and its Application to Pharmacotherapy
-
Kim HC
- KMID: 2286720
- Korean J Psychopharmacol.
- 2007 May;18(3):133-142.
A current hypothesis of sleep-wake regulation proposes that the sleep process starts with the activation of sleep-promoting neurons located in the preoptic area of the anterior hypothalamus. This activation leads... -
- CITED
-
- Close
- SHARE
-
- Close
- Neuroimmunological Activation of Afferent Auditory Neural Circuit in LPS-Induced Otitis Media
-
Jun BC, Kim HT, Song CE, Lee DH, Yeo SW
- KMID: 1977287
- Korean J Otolaryngol-Head Neck Surg.
- 2006 Oct;49(10):978-985.
BACKGROUND AND OBJECTIVES : The goal of this study was to identify the central modulation of the auditory pathway by peripheral inflammation and loud sound exposure, which is associated with... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Phenylephrine on the Excitability of Medial Vestibular Nuclear Neurons in Rats
-
Jeong HS, Huh HR, Jang MJ, Hong SH, Jang S, Park J, Lee SH, Kim JH, Park JS
- KMID: 2285323
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):131-135.
Coeruleo-vestibular pathway which connects locus coeruleus and vestibular nuclei is noradrenergic. This study was designed to elucidate the effects of phenylephrine on the spontaneous activity of acutely isolated medial vestibular... -
- CITED
-
- Close
- SHARE
-
- Close
- Analysis of Electrophysiological Change in the Rat LC Nucleus after Salicylic Acid Treatment
-
Kim SC, Kim SB, Park SY, Jun BH
- KMID: 2276565
- Korean J Otolaryngol-Head Neck Surg.
- 2006 Feb;49(2):148-152.
BACKGROUND AND OBJECTIVES: The precise mechanism of salicylic acid induced tinnitus has not been clearly identified as yet in spite of wide range of studies undertaken. We looked for the... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Chronic Alcohol Exposure on Dopaminergic and Serotonergic Neurotransmission System in Rat
-
Park SW, Lee YC, Ha EK, Kim YK, Lee YK, Chung DO, Ryu JW, Kong BG, Kim YH
- KMID: 2287358
- Korean J Psychopharmacol.
- 2005 Jan;16(1):81-90.
OBJECTIVE: This study investigates the effects of chronic alcohol exposure on rat brain THmRNA expression, TH (tyrosine hydroxylase) acitivity, and TPH (tryptophan hydroxylase) activity which are important in synthesis of... -
- CITED
-
- Close
- SHARE
-
- Close
- In Vivo Microdialysis Measures of Extracellular Norepinephrine in the Rat Amygdala during Sleep-wakefulness
-
Park SP
- KMID: 1101557
- J Korean Med Sci.
- 2002 Jun;17(3):395-399.
- doi: 10.3346/jkms.2002.17.3.395
Norepinephrine (NE)-containing locus ceruleus (LC) has been known to participate in the regulation of the sleep-wake cycle according to the differential firing rate. The aim of this study was to... -
- CITED
-
- Close
- SHARE
-
- Close
- C-fos Expression in Brain Stem of Rats after Salicylic Acid Treatment
-
Kim SC, Jun BH, Choi IS, Jung BJ, Kim DS
- KMID: 2275882
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Mar;45(3):214-218.
BACKGROUND AND OBJECTIVES: Subjective tinnitus, a distracting internal noise, is experienced by humans. Tinnitus is evoked by salicylic acid treatment in rats as confirmed by Jastreboff in 1994 in an... -
- CITED
-
- Close
- SHARE
-
- Close
- Neural Pathway Innervating Epididymis of Rats by Pseudorabies virus (PRV-Ba-Gal) and WGA-HRP
-
Lee CH, Ko BM, Lee BH, Chung OB
- KMID: 1558429
- Korean J Anat.
- 2001 Apr;34(2):141-154.
This experimental studies was to investigate the location of PNS and CNS labeled neurons following injection of 2% WGA-HRP and pseudorabies virus (PRV), beta-galactosidase inserted Bartha strain, into the epididymis... -
- CITED
-
- Close
- SHARE
-
- Close
- The effects of chronic lead exposure on norepinephrinergic neurons of the nucleus locus ceruleus of the rat
-
Lee WT, Yoon H, Lee DJ, Lee JE, Koo CH, Park KA
- KMID: 2224553
- Korean J Anat.
- 2000 Aug;33(4):423-432.
The neurotoxic effects of inorganic lead, a common environmental toxic substance, include peripheral neuropathy in adults and encephalopathy in children. Behavioral changes including hyperactivity, short attention span, easy distractibility and... -
- CITED
-
- Close
- SHARE
-
- Close
- Immunocytochemical Studies of Calbindin D-28k and Parvalbumin-Containing GABAergic Neurons in the Midbrain of the Cat
-
Kim JJ, Jeong SB, Kim NH, Ahn GH, Chung YY, Moon JS, Chang IY, Kim HS
- KMID: 2071859
- Korean J Phys Anthropol.
- 2000 Jun;13(2):201-211.
This study was carried out to investigate the morphology, distribution and co-localization of calbindin D-28k and parvalbumin-containing GABAergic cells in the midbrain of the cat. The results obtain by immunocytochemical... -
- CITED
-
- Close
- SHARE
-
- Close
