- The role of gut-liver axis in the pathogenesis of liver cirrhosis and portal hypertension
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Seo YS, Shah VH
- KMID: 1410889
- Clin Mol Hepatol.
- 2012 Dec;18(4):337-346.
- doi: 10.3350/cmh.2012.18.4.337
Because of the anatomical position and its unique vascular system, the liver is susceptible to the exposure to the microbial products from the gut. Although large amount of microbes colonize... -
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- Effect of Dexamethasone and Epinephrine on Metallothionein Level in the Perfused Rat Liver
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Lee HS, Oh SH
- KMID: 692893
- Yonsei Med J.
- 1980 Jun;21(1):18-23.
- doi: 10.3349/ymj.1980.21.1.18
The effect of dexamethasone (10(-5)M) and epinephrine (10(-6)M) on the biosynthesis of metallothionein (MT) in the perfused rat liver was investigated. MT synthesis was determined by measuring the incorporation of... -
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- Inflammation and Hepatic Fibrosis, Then Hepatocellular Carcinoma
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Kwon OS, Choi SH, Kim JH
- KMID: 2373365
- Korean J Gastroenterol.
- 2015 Dec;66(6):320-324.
- doi: 10.4166/kjg.2015.66.6.320
Inflammation is one of the most prominent characteristic features of chronic liver disease, liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Most of HCC cases develop in patients with cirrhosis and... -
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- Urea Synthesis in the Intact and in the Isolated Perfused Liver of the Biotin-Deficient Rats
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Kim JH, Cho MY, Kim BW, Song CS
- KMID: 687653
- Yonsei Med J.
- 1971 Dec;12(1):13-16.
- doi: 10.3349/ymj.1971.12.1.13
Biotin-deficient rats were raised on a purified ration containing raw egg white plus avidin. Urea synthesis and excretion were compared between the biotin-deficient and the pair-fed control rats. 24hrurinary urea... -
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- The metabolic effects of estriol in female rat liver
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Yang JM, Kim SS, Kim JI, Ahn BM, Choi SW, Kim JK, Lee CD, Chung KW, Sun HS, Park DH, Thurman RG
- KMID: 646306
- J Korean Med Sci.
- 1999 Jun;14(3):277-285.
- doi: 10.3346/jkms.1999.14.3.277
The effects of estriol on oxygen uptake, glucose release, lactate and pyruvate production, beta-hydroxybutyrate and acetoacetate production in perfused rat liver as well as, carbon uptake in rat liver and... -
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- Enhancement of O-dealkylation in Mouse Liver by Dietary Administrations of BHA and BHT: Studies with Isolated Perfused Livers and Hepatic Microsomes
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Ji SC, Conway JG, Thurman RG, Cha YN
- KMID: 693021
- Yonsei Med J.
- 1986 Jun;27(2):106-113.
- doi: 10.3349/ymj.1986.27.2.106
Effects of feeding 2(3)-tert-butyl 4-hydroxyanisole (BHA) and 3, 5-di-tert-butyl 4-hydroxytoluene (BHT) on the rates of mixed function oxidation and conjugation enzyme reactions have been determined using isolated hepatic microsomal fractions... -
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- Nucleolus contains signal molecules that constitute membrane-nucleolus linked pathway
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Jeong JS, Kim IH, Lee HJ, Choi YC
- KMID: 755010
- Exp Mol Med.
- 1998 Dec;30(4):205-213.
Since there have been very few studies on nucleolar signaling, an attempt was made to establish nucleolar signal pathways which link the cell membrane to the nucleolus for the transfer... -
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- Glutathione recycling is attenuated by acute ethanol feeding in rat liver
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Oh SI, Kim CI, Chun HJ, Lee MS, Park SC
- KMID: 1081053
- J Korean Med Sci.
- 1997 Aug;12(4):316-321.
- doi: 10.3346/jkms.1997.12.4.316
The mechanism for ethanol-induced oxidative stress has been disputed because of the controversies on modulation of radical generating and scavenging activities by ethanol. In the present work, we attempted... -
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- Decreased C-reactive protein induces abnormal vascular structure in a rat model of liver dysfunction induced by bile duct ligation
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Jun JH, Choi JH, Bae SH, Oh SH, Kim GJ
- KMID: 2373138
- Clin Mol Hepatol.
- 2016 Sep;22(3):372-381.
- doi: 10.3350/cmh.2016.0032
BACKGROUND/AIMS: Chronic liver disease leads to liver fibrosis, and although the liver does have a certain regenerative capacity, this disease is associated with dysfunction of the liver vessels. C-reactive protein... -
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- Increased expression of Galphaq protein in the heart of streptozotocin-induced diabetic rats
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Yang JM, Cho CH, Kong KA, Jang IS, Kim HW, Juhnn YS
- KMID: 1029924
- Exp Mol Med.
- 1999 Dec;31(4):179-184.
Heart disease is one of the major cause of death in diabetic patients, but the thogenesis of diabetic cardio-myopathy remains unclear. In this experiment, to sess the significance... -
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- Effect of Alloxan-diabetic Rat Fed with Different Diets on Ureogenesis in Isolated Perfused Liver
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Cho MY, Park KK, Chai KJ, Kim YS
- KMID: 692948
- Yonsei Med J.
- 1982 Dec;23(2):159-166.
- doi: 10.3349/ymj.1982.23.2.159
The effect of alloxan-diabetic rat fed with normal, high fat, low protein and high protein diets on the rate of urea production and the activities of enzymes associated with the... -
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- Effect of p-Dimethylaminoazobenzene and 2(3)-tert-Butyl-4-hydroxyanisole on Lipid Pcroxidation, Glutathione-S-transferase, Peroxidase and Reductase in Rat Liver
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Oh SH, Lee MH
- KMID: 934616
- Yonsei Med J.
- 1981 Dec;22(2):95-100.
- doi: 10.3349/ymj.1981.22.2.95
An experiment was conducted in order to investigate the effect of p-dimethylaminoazobenzene (DAB) and 2(3)-tert-butyl-4-hydroxyanisole (BHA) on the lipid peroxidation and peroxide-destroying enzyme system in the rat liver. Dietary supplementation... -
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- Determination of Roxithromycin by Liquid Chromatography/Mass Spectrometry after Multiple-Dose Oral Administration in Broilers
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Lim JH, Park BK, Yun HI
- KMID: 1099819
- J Vet Sci.
- 2003 Apr;4(1):35-39.
A highly sensitive and specific method for the determination of roxithromycin in broiler tissues by LC/MS was developed and validated. A dichloromethane extract of the sample was separated on C18... -
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- Changes in expression of cell cycle regulators and their hepatic lobular distribution in partial hepatectomy-induced regenerating rat liver
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Jeong JS, Lee JH, Kim HI, Park JI
- KMID: 646039
- J Korean Med Sci.
- 1999 Dec;14(6):635-642.
- doi: 10.3346/jkms.1999.14.6.635
Partial hepatectomy (PH) endorses quiescent hepatocytes to reenter the cell cycle. The regenerating liver returns to its preresection weight after 7 days, following one or two cell division and maintains... -
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- Transforming growth factor-beta1 protein, proliferation and apoptosis of oval cells in acetylaminofluorene-induced rat liver regeneration
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Park DY, Suh KS
- KMID: 646021
- J Korean Med Sci.
- 1999 Oct;14(5):531-538.
- doi: 10.3346/jkms.1999.14.5.531
Administering of 2-acetylaminofluorene (2-AAF) before a two-thirds partial hepatectomy (PHx) results in suppression of hepatocyte proliferation and stimulation of oval cell proliferation. The objectives of this study was to examine... -
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- Expression of hepatitis C virus nonstructural 4B in transgenic mice
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Wang AG, Moon HB, Kim JM, Hwang SB, Yu DY, Lee DS
- KMID: 1094149
- Exp Mol Med.
- 2006 Jun;38(3):241-246.
Hepatitis C virus (HCV) is a pathogen that is of great medical significance in chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. Although the HCV proteins have been intensively investigated... -
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- Identification and characterization of peroxisome proliferator response element in the mouse GLUT2 promoter
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Im SS, Kim JW, Kim TH, Song XL, Kim SY, Kim HI, Ahn YH
- KMID: 755748
- Exp Mol Med.
- 2005 Apr;37(2):101-110.
In the present study, we show that the expression of type 2 glucose transporter isoform (GLUT2) could be regulated by PPAR-gamma in the liver. Rosiglitazone, PPAR-gamma agonist, activated the GLUT2... -
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- Surgical removal of visceral fat decreases plasma free fatty acid and increases insulin sensitivity on liver and peripheral tissue in monosodium glutamate (MSG)-obese rats
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Kim YW, Kim JY, Lee SK
- KMID: 646022
- J Korean Med Sci.
- 1999 Oct;14(5):539-545.
- doi: 10.3346/jkms.1999.14.5.539
In order to evaluate the role of visceral and subcutaneous fat tissue in insulin sensitivity and lipid metabolism, we measured the fasting levels of plasma free fatty acid (FFA) and... -
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- Studies on the Hepatic Accumulation of Triglyceride Induced by Chronic Ethanol Administration in Rats Fed with Various Diets
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Cho MY, Choi BS, Kim YS
- KMID: 692892
- Yonsei Med J.
- 1980 Jun;21(1):9-17.
- doi: 10.3349/ymj.1980.21.1.9
Investigation in our laboratory has been undertaken to study the effect of ethanol on the triglyceride (TG) content in the liver, the free fatty acid (FFA) content in the serum... -
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- HNF1 and/or HNF3 may contribute to the tissue specific expression of glucokinase gene
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Cha JY, Kim HI, Im SS, Li TZ, Ahn YH
- KMID: 1085740
- Exp Mol Med.
- 2001 Jun;33(2):59-63.
A possible role of hepatocyte nuclear factor 1 (HNF1) or HNF3, a predominant trans-acting factors of hepatic or pancreatic beta-cells, was examined on the tissue specific interdependent expression of glucokinase... -
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