- Development and validation of analytical method for the determination of radotinib in human plasma using liquid chromatography-tandem mass spectrometry
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Seo HB, Cho S, Yoon YR, Yim DS
- KMID: 2407000
- Transl Clin Pharmacol.
- 2017 Dec;25(4):183-189.
- doi: 10.12793/tcp.2017.25.4.183
This study describes the development of an analytical method to determine radotinib levels in human plasma using high performance liquid chromatography (HPLC) coupled with triple quadrupole tandem mass spectrometry (MS/MS)... -
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- Determination of donepezil in human plasma using ultra performance liquid chromatography-tandem mass spectrometry
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Jeong HC, Park JE, Hyun JY, Park MK, Shin DS, Shin KH
- KMID: 2413829
- Transl Clin Pharmacol.
- 2018 Jun;26(2):64-72.
- doi: 10.12793/tcp.2018.26.2.64
An ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed and validated for the quantification of donepezil in human plasma. Donepezil and donepezil-D4 were extracted from human plasma by... -
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- Safety, Efficacy, and Physicochemical Characterization of Tinospora crispa Ointment: A Community-Based Formulation against Pediculus humanus capitis
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Torre GL, Ponsaran K, de Guzman , Manalo RA, Arollado E
- KMID: 2389976
- Korean J Parasitol.
- 2017 Aug;55(4):409-416.
- doi: 10.3347/kjp.2017.55.4.409
The high prevalence of pediculosis capitis, commonly known as head lice (Pediculus humanus capitis) infestation, has led to the preparation of a community-based pediculicidal ointment, which is made of common... -
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- Development of a simple and sensitive HPLC-MS/MS method for determination of diazepam in human plasma and its application to a bioequivalence study
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Kim DH, Cho JY, Chae SI, Kang BK, An TG, Shim WS, Noh YS, Hwang SJ, Chung EK, Lee KT
- KMID: 2406998
- Transl Clin Pharmacol.
- 2017 Dec;25(4):173-178.
- doi: 10.12793/tcp.2017.25.4.173
We developed a simple, sensitive, and effective ultra-performance liquid chromatography/tandem mass spectrometry (HPLC-MS/MS) method with an electrospray ionization (ESI) interface in multiple reaction monitoring (MRM) and positive ion modes to... -
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- Development of a LC-MS/MS for Quantification of Venlafaxine in Human Plasma and Application to Bioequivalence Study in healthy Korean Subjects
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Kang HK, Kang MA, Kim HJ, Park YS, Kim SH, Kang JS
- KMID: 2317857
- Transl Clin Pharmacol.
- 2014 Jun;22(1):35-42.
A simple, rapid and selective liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) is developed and validated for quantification of venlafaxine in human plasma with simple liquid-liquid extraction step consisted... -
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- Measurement of Serum Levels of 25-Hydroxyvitamin D3 and 25-Hydroxyvitamin D2 Using Diels-Alder Derivatization and Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry
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Kim H, Jun SH, Kim T, Song SH, Park KU, Song J
- KMID: 2312205
- Lab Med Online.
- 2012 Oct;2(4):188-196.
BACKGROUND: Vitamin D has been recently shown to play important roles in the functioning of various systems. Most of the current analytical methods for measuring vitamin D levels are based... -
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- Removing Lipemia in Serum/Plasma Samples: A Multicenter Study
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Castro-Castro MJ, Candás-Estébanez B, Esteban-Salán M, Calmarza P, Arrobas-Velilla T, Romero-Román C, PocovÃ-Mieras M, Aguilar-Doreste JA, on behalf of the Commission on Lipoprotein and Vascular Diseases, Sociedad Española de QuÃmica ClÃnica
- KMID: 2429116
- Ann Lab Med.
- 2018 Nov;38(6):518-523.
- doi: 10.3343/alm.2018.38.6.518
BACKGROUND: Lipemia, a significant source of analytical errors in clinical laboratory settings, should be removed prior to measuring biochemical parameters. We investigated whether lipemia in serum/plasma samples can be removed... -
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- Development of a validated liquid chromatography-tandem mass spectrometry assay for the quantification of simvastatin acid, the active metabolite of simvastatin, in human plasma
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Park HJ, Hwang AK, Kim AR, Kim SH, Kim EH, Cho SH, Ghim JL, Choe S, Jung JA, Jin SJ, Bae KS, Lim HS
- KMID: 2383596
- Transl Clin Pharmacol.
- 2016 Mar;24(1):22-29.
- doi: 10.12793/tcp.2016.24.1.22
Simvastatin is a lipid-lowering drug that is metabolized to its active metabolite simvastatin acid (SA). We developed and validated a sensitive liquid chromatography-tandem mass spectrometry (LC/MS/MS) method to quantitate SA... -
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