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A Case of Leukemia Cutis in Myelodysplastic Syndrome Evolving into An Atypical Chronic Myeloid Leukemia

Ryu HJ, Kye YC, Kim SN

We report a patient who had been initially diagnosed as a myelodysplastic syndrome in 1998 presenting purpuric patches on the left arm that started to develop about a year prior....
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Four Cases of Atypical Chronic Myeloid Leukemia

Yoo SJ, Kang SG, Seo EJ, Park CJ, Lee KH, Chi HS

  • KMID: 2146087
  • Korean J Clin Pathol.
  • 2002 Apr;22(2):75-79.
Four cases of atypical chronic myeloid leukemia (aCML), which were compatible with the FAB guideline for the classification of chronic myeloid leukemia (CML), are presented. All 4 patients showed the...
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Technetium-99m MDP bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia

Kwak HS, Sohn MH, Lim ST, Kwak JY, Yim CY

Hypercalcemia in accelerated phase of chronic myelogenous leukemia (CML) is very rare. Its pathogenesis is considered humoral hypercalcemia of malignancies mediated by parathyroid hormone-related protein (PTHrP). In severe hypercalcemia, calcifications...
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Renal Involvement of Chronic Myelogenous Leukemia Presenting as a Kidney Tumor

Go JH

Renal involvement by leukemic cells is rare in chronic myelogenous leukemia (CML). Herein, this study reports a case of CML associated with renal involvement of leukemic cells, which occurred 1...
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Characteristics and survival of patients with atypical chronic myeloid leukemia

Kong JH, Nam H, Go TH, Hyun SY, Shim KY

No abstract available.
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A Case of Leukemic Pleural Infiltration in Atypical Chronic Myeloid Leukemia

Kim HW, Lee SS, Ryu MH, Lee JL, Chang HM, Kim TW, Chi HS, Kim WK, Lee JS, Kang YK

Pleural effusion in chronic myeloid leukemia (CML) is poorly understood and rarely reported in the literature. When the pleural effusion is caused by leukemic pleural infiltration, the differential white blood...
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Investigation of the Bovine Leukemia Virus Proviral DNA in Human Leukemias and Lung cancers in Korea

Lee J, Kim Y, Kang CS, Cho DH, Shin DH, Yum YN, Oh JH, Kim SH, Hwang MS, Lim CJ, Yang KH, Han K

The bovine leukemia virus (BLV) is the causative agent of enzootic bovine leucosis. This study investigated the presence of the BLV in leukemia (179 acute lymphoblastic leukemia, 292 acute myeloid...
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A Case of Avascular Necrosis of the Femoral Head as Initial Presentation of Chronic Myelogenous Leukemia

Moon JY, Kim BS, Yun HR, Choi JH, Lee YY, Kim IS, Ahn MJ

Chronic myelogenous leukemia (CML) is a malignant clonal disorder of hemopoietic stem cells characterized by abnormal proliferation and accumulation of immature granulocyte. Leukostasis is one of the complications of CML...
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A Case of Atypical Chronic Myeloid Leukemia with the JAK2V617F Mutation

Kim JY, Lee SR, Nam MH, Yoon SY, Lim CS, Lee CK, Kim BS, Cho Y, Kim YK, Lee KN

Atypical chronic myeloid leukemia (aCML) is a rare leukemic disorder that shows myelodysplastic and myeloproliferative features simultaneously. The Janus kinase 2 gene V617F mutation (JAK2V617F) in aCML has been the...
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Multiple myeloma and chronic myelogenous leukemia: a case report with literature review

Klenn PJ, Hyun BH, Lee YH, Zheng WY

This is the case of a 71 year old male who developed multiple myeloma (MM) and chronic myelogenous leukemia (CML) within a two year period. The patient initially presented with...
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Allogeneic hematopoietic cell transplantation in adult patients with myelodysplastic/myeloproliferative neoplasms

Lim SN, Lee JH, Lee JH, Kim DY, Kim SD, Kang YA, Lee YS, Lee KH

BACKGROUND: In adults, the 2 main types of myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are chronic myelomonocytic leukemia (CMML) and atypical chronic myeloid leukemia (aCML). Both are associated with a poor prognosis. Allogeneic...
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Five cases of cytomegalovirus infection detected by in situ hybridization and antigenemia assay

Yoo JH, Choi JY, Kim YR, Choi YJ, Shim SI, Kim HK, Yang CW, Kim YS, Hahn CW, Shin WS, Park CW, Kang MW, Kim CC, Bang BK, Kim DJ

We report five cases of cytomegalovirus infection in immunocompromised patients which were detected by either cytomegalovirus antigenemia assay or in situ hybridization. Four cases had leukemia and the other had...
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Hydroxyurea Induced Perimalleolar Ulcers

Saravu K, Velappan P, Lakshmi N, Shastry BA, Thomas J

Hydroxyurea (HU) is an antineoplastic drug commonly used to treat chronic myeloproliferative disorders. Common dermatological side effects include hyperpigmentation, scaling, erythema, alopecia, desquamation of face and hands. Leg ulceration following...
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Myeloablative Treatment Supported by Autologous Stem Cell Infusion with Neuroblastoma

Ryu KH, Seoh JY, Jang PS, Kim CW, Koh SH, Shin HY, Ahn HS

Bcr-abl antisense oligodeoxynucleotides (AS-ODNs) have provided evidence of an antileukemia effect when tested in vitro against Philadelphia-positive cells. In order to investigate the efficacy of AS-ODNs as purging agents in...
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Efficacy of in vitro treatment of chronic myelogenous leukemia cell line, K562 cells, using 4-hydroperoxycyclophosphamide, alpha-interferon and gamma-interferon

Lee JT, Park S, Lee JH, Kim BK, Kim NK

Alpha-interferon (alpha-IFN) and gamma-interferon (gamma-IFN) are highly effective biologic agents in the treatment of chronic myelogenous leukemia (CML). 4-hydroperoxycyclophosphamide (4-HC) is the most commonly used chemotherapeutic drug when purging bone...
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Topotecan-based combination chemotherapy in patients with transformed chronic myelogenous leukemia and advanced myelodysplastic syndrome

Park SJ, Kim DW, Kim HJ, Eom HS, Min CK, Lee JW, Min WS, Kim CC

  • KMID: 759504
  • Korean J Intern Med.
  • 2000 Jul;15(2):122-126.
BACKGROUND: Patients with transformed chronic myelogenous leukemia(CML) and advanced myelodysplastic syndrome(MDS) have poor prognosis. The aim of this study is to evaluate the feasibility of second chronic phase...
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Varying expression levels of colony stimulating factor receptors in disease states and different leukocytes

Lee KY, Suh BG, Kim JW, Lee WB, Kim SY, Kim YY, Lee JH, Lim JH, Lim MS, Kang CS, Han KJ

  • KMID: 755101
  • Exp Mol Med.
  • 2000 Dec;32(4):210-215.
Administration of G-CSF may not always respond in rise of neutrophil counts in different patient population. In order to understand a possible inter-relationship between the G-CSF and GM-CSF...
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