- A Case of Nonketotic Hyperglycemia as a Manifestation of Generalized Convulsive Status Epilepticus
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Leem J, Lee JJ, Han JM, Kim YS, Yu JH, Jung CH, Lee WJ
- KMID: 2263745
- Korean J Med.
- 2011 Oct;81(4):508-511.
Seizure is one of the manifestations of nonketotic hyperglycemia (NKH). Partial motor seizures are observed in most cases and, occasionally, with epilepsia partialis continua. Generalized convulsive status epilepticus caused by... -
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- Estimation of Demand and Supply for Occupational and Environmental Medicine Specialties in Korea (I): Estimation of Supply
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Kim J, Chae Y, Leem J
- KMID: 2075081
- Korean J Occup Environ Med.
- 2011 Mar;23(1):71-79.
OBJECTIVES: To estimate the supply of occupational and environmental medicine specialties in the target year of 2020. METHODS: We adopted alternative projection models combined with a demographic method as a supply... -
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- Management of Non-alcoholic Fatty Liver Disease
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Leem J, Koh EH
- KMID: 2173900
- J Korean Diabetes.
- 2014 Jun;15(2):93-97.
- doi: 10.4093/jkd.2014.15.2.93
Non-alcoholic fatty liver disease (NAFLD) is a common condition that may progress to end-stage liver disease. Recently, it has been recognized as a hepatic manifestation of metabolic syndrome and an... -
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- Estimation of Demand and Supply for Occupational and Environmental Medicine Specialties in Korea (II): Demand Estimation and Demand-Supply Balance
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Chae Y, Kim J, Leem J
- KMID: 2075082
- Korean J Occup Environ Med.
- 2011 Mar;23(1):80-88.
OBJECTIVES: To estimate the demand and demand-supply balances of occupational and environmental medical specialties (OEMS) in the target year of 2020. METHODS: We adopted a new OEMS demand model based on... -
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- Disseminated Mycobacterium intracellulare Infection in an Immunocompetent Host
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Kim WY, Jang SJ, Ok T, Kim GU, Park HS, Leem J, Kang BH, Park SJ, Oh DK, Kang BJ, Lee BY, Ji WJ, Shim TS
- KMID: 2319820
- Tuberc Respir Dis.
- 2012 May;72(5):452-456.
Disseminated Mycobacterium avium complex (MAC) infection can occur in immunocompromised patients, and rarely in immunocompetent subjects. Due to the extensive distribution of the disease, clinical presentation of disseminated MAC may... -
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- Mechanisms of Vascular Calcification: The Pivotal Role of Pyruvate Dehydrogenase Kinase 4
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Leem J, Lee IK
- KMID: 2169692
- Endocrinol Metab.
- 2016 Mar;31(1):52-61.
- doi: 10.3803/EnM.2016.31.1.52
Vascular calcification, abnormal mineralization of the vessel wall, is frequently associated with aging, atherosclerosis, diabetes mellitus, and chronic kidney disease. Vascular calcification is a key risk factor for many adverse... -
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- Fatal Rhabdomyolysis in a Patient with Liver Cirrhosis after Switching from Simvastatin to Fluvastatin
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Baek SD, Jang SJ, Park SE, Ok TJ, Leem J, Lee HS, Park SJ, Kim TH
- KMID: 1786022
- J Korean Med Sci.
- 2011 Dec;26(12):1634-1637.
- doi: 10.3346/jkms.2011.26.12.1634
HMG-CoA reductase inhibitors (statins) are widely used to treat hypercholesterolemia. Among the adverse effects associated with these drugs are statin-associated myopathies, ranging from asymptomatic elevation of serum creatine kinase to... -
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- Clinical Features and Causes of Endogenous Hyperinsulinemic Hypoglycemia in Korea
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Woo CY, Jeong JY, Jang JE, Leem J, Jung CH, Koh EH, Lee WJ, Kim MS, Park JY, Lee JB, Lee KU
- KMID: 1805895
- Diabetes Metab J.
- 2015 Apr;39(2):126-131.
- doi: 10.4093/dmj.2015.39.2.126
BACKGROUND: Endogenous hyperinsulinemic hypoglycemia (EHH) is characterized by an inappropriately high plasma insulin level, despite a low plasma glucose level. Most of the EHH cases are caused by insulinoma, whereas... -
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- Serum Ceruloplasmin Level as a Predictor for the Progression of Diabetic Nephropathy in Korean Men with Type 2 Diabetes Mellitus
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Lee MJ, Jung CH, Kang YM, Jang JE, Leem J, Park JY, Lee WJ
- KMID: 2281536
- Diabetes Metab J.
- 2015 Jun;39(3):230-239.
- doi: 10.4093/dmj.2015.39.3.230
BACKGROUND: Oxidative stress is known to be associated with progression of diabetic kidney disease. Ceruloplasmin acts as a pro-oxidant under conditions of severe oxidative stress. Thus, we conducted a longitudinal... -
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- Serum Total Bilirubin Levels Provide Additive Risk Information over the Framingham Risk Score for Identifying Asymptomatic Diabetic Patients at Higher Risk for Coronary Artery Stenosis
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Leem J, Koh EH, Jang JE, Woo CY, Oh JS, Lee MJ, Kang JW, Lim TH, Jung CH, Lee WJ, Park JY, Lee KU
- KMID: 2174015
- Diabetes Metab J.
- 2015 Oct;39(5):414-423.
- doi: 10.4093/dmj.2015.39.5.414
BACKGROUND: The diagnosis of coronary artery disease (CAD) is often delayed in patients with type 2 diabetes. Serum total bilirubin levels are inversely associated with CAD. However, no studies have... -
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- Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes
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Jeon MJ, Leem J, Ko MS, Jang JE, Park HS, Kim HS, Kim M, Kim EH, Yoo HJ, Lee CH, Park IS, Lee KU, Koh EH
- KMID: 1389736
- Exp Mol Med.
- 2012 Sep;44(9):562-570.
Mitochondrial dysfunction and endoplasmic reticulum (ER) stress are considered the key determinants of insulin resistance. Impaired mitochondrial function in obese animals was shown to induce the ER stress response, resulting... -
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- Myricetin Protects Against High Glucose-Induced β-Cell Apoptosis by Attenuating Endoplasmic Reticulum Stress via Inactivation of Cyclin-Dependent Kinase 5
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Karunakaran U, Elumalai S, Moon JS, Jeon JH, Kim ND, Park KG, Won KC, Leem J, Lee IK
- KMID: 2442772
- Diabetes Metab J.
- 2019 Apr;43(2):192-205.
- doi: 10.4093/dmj.2018.0052
BACKGROUND: Chronic hyperglycemia has deleterious effects on pancreatic β-cell function and turnover. Recent studies support the view that cyclin-dependent kinase 5 (CDK5) plays a role in β-cell failure under hyperglycemic... -
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