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Clinical Significance of Inflammatory Biomarkers in Acute Pediatric Diarrhea

Park Y, Son M, Jekarl DW, Choi HY, Kim SY, Lee S

PURPOSE: The aim of this study was to evaluate the clinical significance of inflammatory biomarkers in acute infectious diarrhea among children. METHODS: Clinical parameters including fever, bacterial and viral etiology based...
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Development and properties of hypoallergenic infant formula

Ha WK, Lee J, Kim KE

Milk proteins are composed of casein, further classified into αS1-casein, αS2-casein, β-casein, and κ-casein, and whey protein, which is separated into α-lacatalbumin, β-lactoglobulin, serum albumin, and some minor proteins, such...
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Molecular Defense Mechanisms during Urinary Tract Infection

Choi SY, Chang IH

The urinary tract is a common site of infection. The complete mechanisms of urinary tract infection (UTI) are still unknown. In general, the strategies of the uropathogenic Escherichia coli are...
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Clinical Significance of Fecal Lactoferrin and Multiplex Polymerase Chain Reaction in Patients with Acute Diarrhea

Lee HM, Lee S, Lee BI, Jekarl DW, Song JY, Choi HJ, Kang BK, Im EJ, Kim JS, Kim JI, Kim BW, Choi H

BACKGROUND/AIMS: The diagnostic yield of fecal leukocyte and stool cultures is unsatisfactory in patients with acute diarrhea. This study was performed to evaluate the clinical significance of the fecal lactoferrin...
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The effect of two artificial salivas on the adhesion of Candida albicans to heat-polymerized acrylic resin

Oncul B, Karakis D, Dogruman Al F

PURPOSE: Xerostomia can diminish the quality of life, leads to changes in normal chemical composition of saliva and oral microbiata, and increases the risk for opportunistic infections, such as Candida...
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Lactoferrin Combined with Retinoic Acid Stimulates B1 Cells to Express IgA Isotype and Gut-homing Molecules

Kang SH, Jin BR, Kim HJ, Seo GY, Jang YS, Kim SJ, An SJ, Park SR, Kim WS, Kim PH

It is well established that TGF-beta1 and retinoic acid (RA) cause IgA isotype switching in mice. We recently found that lactoferrin (LF) also has an activity of IgA isotype switching...
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Lactoferrin Constitutively Enhances Differentiation of Osteoblastic MC3T3-E1 Cells in Vitro

Yang HY, Lee HM, Park BJ, Lee TH

  • KMID: 1727432
  • Int J Oral Biol.
  • 2014 Sep;39(3):145-151.
During bone remodeling, there is requirement of differentiation of osteoblastic cells. Previously, we identified proteins differentially expressed in soft tissue during bone healing. Of these proteins, we focused the effect...
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Intestinal Microbiota in Preterm Infants and Probiotics Use for Disease Prevention

Kim ES

Infectious complications such as necrotizing enterocolitis (NEC) or neonatal sepsis are main causes of mortality and disability in very low birth weight infants (VLBWIs). Because preterm infants are exposed to...
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Prevention of Fungal Infection in Neonatal Intensive Care Unit

Choi YY

  • KMID: 2312949
  • Neonatal Med.
  • 2013 Aug;20(3):361-368.
Although advances in neonatal intensive care have led to an improved survival rate of extremely low birth weight infants, prolonged hospitalization of these critically ill infants has rendered them to...
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Fecal Biomarkers in Inflammatory Bowel Disease

Lee KM

Inflammatory bowel diseases (IBD) are idiopathic, remitting and relapsing diseases causing chronic inflammation of intestine. Initial diagnosis, assessment of disease activity, and prediction of treatment outcomes present challenges to physicians...
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Lactoferrin Stimulates Mouse Macrophage to Express BAFF via Smad3 Pathway

Chang H, Jin BR, Jang YS, Kim WS, Kim PH

B cell-activating factor belonging to the TNF family (BAFF) is primarily expressed by macrophages and stimulates B cell proliferation, differentiation, survival, and Ig production. In this study, we explored the...
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An update on necrotizing enterocolitis: pathogenesis and preventive strategies

Lee JH

Necrotizing enterocolitis (NEC) is one of the most critical morbidities in preterm infants. The incidence of NEC is 7% in very-low-birth-weight infants, and its mortality is 15 to 30%. Infants...
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The stress of weaning influences serum levels of acute-phase proteins, iron-binding proteins, inflammatory cytokines, cortisol, and leukocyte subsets in Holstein calves

Kim MH, Yang JY, Upadhaya S, Lee HJ, Yun CH, Ha JK

The purpose of our study was to investigate changes in immunological parameters induced by weaning stress (including milk restriction) in calves. Fifteen Holstein calves were subjected to weaning at 6...
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Activation of Lysozyme and Lactoferrin in Endolymphatic Duct of Rats

Choi SC, Ahn JY, Lee HJ, Kang SH, Kim BH, Lim DJ, Do HJ, Jung YS

BACKGROUND AND OBJECTIVES: Secretory activity, particularly of antibacterial agents such as lysozyme and lactoferrin, is an important aspect of the mucosal defense mechanism. The development of these agents may have...
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Clinical Significance of Nasal Secretory Proteins in Chronic Sinonasal Diseases

Choi JC, Kim MW, Cho MJ, Yoon JH, Kim JY

  • KMID: 2276717
  • Korean J Otolaryngol-Head Neck Surg.
  • 2007 Mar;50(3):229-234.
BACKGROUND AND OBJECTIVES: Many studies report changes in the expressions of nasal secretory proteins which play important roles in the evaluation of sinonasal mucosal status. The biomarkers in nasal secretions...
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Serum and Cerebrospinal Fluid(CSF) Nitric Oxide, Macrophage Inflammatory Protein-1 alpha and Lactoferrin Levels in Aseptic Meningitis

Seo Y, Shim JY, Shim JW, Kim DS, Jung HL, Park MS

  • KMID: 2279601
  • Korean J Pediatr.
  • 2005 Jan;48(1):48-54.
PURPOSE: The pathologic mechanisms of central nervous system(CNS) injuries in human meningitis are not yet completely understood. Recent studies indicate that the host inflammatory responses are as important in brain...
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Identification of UVB Effects on Gene Expressed by Normal Human Melanocytes

Kim HS, Park HH, Lee MH

  • KMID: 1977852
  • Korean J Dermatol.
  • 2003 Dec;41(12):1597-1602.
BACKGROUND: Irradiation of the skin with ultraviolet rays result in alterations of immune response as well as melanogenesis and melanocarcinogenensis. These effects are largely mediated by soluble mediators released from...
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Lactoferrin Sequestration and Its Contribution to Iron Deficiency Anemia in Helicobacter pylori Infected Gastric Mucosa

Moon KB, Kang CK, Choe YH, Han HS, Song SU

  • KMID: 2275150
  • Korean J Pediatr Gastroenterol Nutr.
  • 2002 Mar;5(1):11-18.
PURPOSE: It is known that lactoferrin serves as a source of iron for H. pylori in gastric mucosa. This study was undertaken to investigate the relationship between lactoferrin and H....
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The Changes of Tear Osmolarity and Protein After Silicone Punctal Plug Insertion In Dry Eye

Lee EH, Jang JW, Lew HM

  • KMID: 2124929
  • J Korean Ophthalmol Soc.
  • 2001 Nov;42(11):1509-1514.
PURPOSE: To evaluate the changes of tear osmolarity and protein after silicone punctal plug insertion in dry eye. METHODS: We collected tear from 21 dry eyes (11 males and 10...
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ADHESION OF CANDIDA ALBICANS ISOLATES TO ACRYLIC RESIN IN RELATION TO SALIVARY GLYCOPROTEINS IN DENTURE STOMATITIS PATIENTS

Oh JH, Choi BB, Choi DG, Woo YH, Lee SB, Kwon KR

  • KMID: 1907066
  • J Korean Acad Prosthodont.
  • 1999 Oct;37(5):698-713.
Adherence of Candida albicans(C. albicans) to the surface of a denture is believed to be an initial and essential step in the formation of denture-induced stomatitis. Previous studies have provided...
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