- The Effects of Oxalate on the DNA Synthesis in LLC-PK1 Cells
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Jung BC, Kim HH, Kim SW
- KMID: 1583002
- Korean J Urol.
- 2000 Apr;41(4):512-515.
No abstract available. -
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- Effects of 2,3,7,8-tetrachlorodibenzo- p-dioxin(TCDD) on Glomerular Mesangial and Tubular Epithelial Cell Activation
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Kim EN, Yu MR, Lim HJ, Hwang EW, Ha HJ, Lee HB
- KMID: 2254450
- Korean J Nephrol.
- 2002 Jan;21(1):12-19.
BACKGROUND: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a prototype compound of polyhalogenated aromatic hydrocarbons, produces diverse biologic effects. Although nephrotoxicity of aromatic hydrocarbons such as benzo[a]pyrene(BP) is well known, little is known about the... -
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- Antioxidative effects of fermented sesame sauce against hydrogen peroxide-induced oxidative damage in LLC-PK1 porcine renal tubule cells
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Song JL, Choi JH, Seo JH, Kil JH, Park KY
- KMID: 2313721
- Nutr Res Pract.
- 2014 Apr;8(2):138-145.
BACKGROUND/OBJECTIVES: This study was performed to investigate the in vitro antioxidant and cytoprotective effects of fermented sesame sauce (FSeS) against hydrogen peroxide (H2O2)-induced oxidative damage in renal proximal tubule LLC-PK1... -
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- Blockade of P-Glycoprotein Decreased the Disposition of Phenformin and Increased Plasma Lactate Level
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Choi MK, Song IS
- KMID: 2170533
- Biomol Ther.
- 2016 Mar;24(2):199-205.
- doi: 10.4062/biomolther.2015.087
This study aimed to investigate the in vivo relevance of P-glycoprotein (P-gp) in the pharmacokinetics and adverse effect of phenformin. To investigate the involvement of P-gp in the transport of... -
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- Effect of cisplatin on sodium-dependent hexose transport in LLC-PK-1 renal epithelial cells
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Lee SK, Kim JY, Yu TH, Kim KR, Kim KH, Park YS
- KMID: 2285156
- Korean J Physiol Pharmacol.
- 1997 Feb;1(1):35-43.
Cis-dichlorodiammine platinum II (Cisplatin), an effective chemotherapeutic agent, induces acute renal failure by unknown mechanisms. To investigate direct toxic effects of cisplatin on the renal proximal tubular transport system, LLC-PK-1 cell line was selected... -
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- The Study on the Mechanism Regulating the Production of Extracellular Matrix in Renal Tubular Epithelial Cells Cultured in High Glucose Concentration
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Hwang JH, Yoo TH, Song HY, Kim JS, Song YS, Chong DL, Kim KS, Kang SW, Lee HY, Han DS, Choi KH
- KMID: 2254580
- Korean J Nephrol.
- 2000 Jan;19(1):31-39.
Thickening of tubular basement membrane and progressive tubulointerstitial fibrosis has been reported as important components of diabetic nephropathy, In order to investigate the mechanisms of tubulinterstitial changes in diabetic nephropathy,... -
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- Poly(ADP-ribose) polymerase regulates glycolytic activity in kidney proximal tubule epithelial cells
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Song H, Yoon SP, Kim J
- KMID: 2308914
- Anat Cell Biol.
- 2016 Jun;49(2):79-87.
- doi: 10.5115/acb.2016.49.2.79
After renal injury, selective damage occurs in the proximal tubules as a result of inhibition of glycolysis. The molecular mechanism of damage is not known. Poly(ADP-ribose) polymerase (PARP) activation plays... -
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- The Study on the Mechanism of Cyclosporine A-induced Nephroptoxicity: The Effects of Ceramide and Phospholipase A2 on Cyclosporine A-induced Apoptosis of Renal Tubular Epithelial Cells
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Choi KH, Jeong HJ, Kwon HY, Kim SI
- KMID: 2324292
- J Korean Soc Transplant.
- 2002 Jun;16(1):9-15.
PURPOSE: In order to elucidate the mechanisms mediating cyclosporine A (CsA)-induced renal tubular cell injury, we examined the effects of ceramide, second messenger derived from sphingolipid breakdown, and phospholipase A2... -
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- The Study on the Mechanism of Cyclosporine A Induced Apoptosis in Renal Tubular Epithelial Cells
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Kim SI, Choi KH, Chong DL, Kim KS
- KMID: 2198927
- J Korean Soc Transplant.
- 1999 Jun;13(1):9-18.
A major limiting factor in the use of cyclosporine A (CsA) is nephrotoxicity, but the mechanisms of nephrotoxicity are not fully understood. In order to elucidate the pathogenesis of CsA... -
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- Antioxidative effects of Kimchi under different fermentation stage on radical-induced oxidative stress
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Kim BK, Choi JM, Kang SA, Park KY, Cho EJ
- KMID: 2313790
- Nutr Res Pract.
- 2014 Dec;8(6):638-643.
- doi: 10.4162/nrp.2014.8.6.638
BACKGROUND/OBJECTIVES: Kimchi is a traditional Korean fermented vegetable containing several ingredients. We investigated the protective activity of methanol extract of kimchi under different fermentation stages against oxidative damage. MATERIALS/METHODS: Fresh kimchi... -
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- In Vitro and In Vivo Effect of Parathyroid Hormone Analogue (1-14) Containing alpha-amino-iso-butyric Acid Residue (Aib)1,3
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Rhee Y, Lee W, Lee EJ, Ma S, Park SY, Lim SK
- KMID: 1110745
- Yonsei Med J.
- 2006 Apr;47(2):214-222.
- doi: 10.3349/ymj.2006.47.2.214
Firstly, parathyroid hormone (1-14) [PTH (1-14)] analogue containing various alpha-amino-iso-butyric acid residue (Aib) was synthesized by exchanging the 1st and 3rd Ala residues of alpha carbon of PTH (1-14). This... -
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- Structure and Function of a Minimal Receptor Activation Domain of Parathyroid Hormone
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Lee EJ, Kim HY, Cho MK, Lee W, Lim SK
- KMID: 1734123
- Yonsei Med J.
- 2004 Jun;45(3):419-427.
- doi: 10.3349/ymj.2004.45.3.419
The structure and function of short-length amino terminal PTH analogues were studied. The substitution of Leu7 with Phe in [Ala3, 10Leu7Arg11]rPTH (1-11) NH2 analogue peptides did not show any reduction... -
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