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Evidence for the Presence of a cis-acting Element in the Coding Region of the Japanese Encephalitis Virus Capsid Protein

Yun SI, Choi YJ, Song BH, Kim JM, Kang SY, Lee YM

Japanese encephalitis virus (JEV) is a member of mosquito-borne flaviviruses. To investigate whether there is a cis-acting genetic element in the coding region of the JEV C protein, which is...
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Screening of Peptide Libraries to Investigate the Substrate Specificity of UL97 Protein Kinase from Human Cytomegalovirus

Baek MC

Human cytomegalovirus encodes an unusual protein kinase UL97 which can phosphorylate exogenous substrates, including histone H2B and nucleoside analogs such as ganciclovir. The previous result interestingly showed that the peptides...
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Development of Peptide Antibody against Coxsackievirus B3 VP2

Chung SY, Cho YJ, Kim YJ, Kim DS, Lee H, Nam JH

Coxsackievirus B3 (CVB3) is the nonenveloped virus containing a single-stranded positive-sense RNA as a genome. CVB3 infection can induce acute myocarditis and dilated cardiomypathy. CVB3 of icosahedral symmetry has four...
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Construction of Recombinant DNA with F and HN Genes of Newcastle Disease Virus and Its Immunogenicity

Kim JY, Chu J, Park JH, Seo SH, Park CS, Kim MC, Jun MH

Recombinant DNA vaccines, based on plasmid vectors expressing an antigen under the control of a strong promotor, have several advantages over traditional vaccines. They have been shown to induce a...
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Host Gene Profiling of Coxsackievirus B3 H3- and 10A1-infected Mouse Heart

Nam JH, Lim BK, Cho YJ, Kim DS, Kim YJ, Chung SY, Jee YM, Jeon ES

Coxsackievirus B3 (CVB3) is a non-enveloped virus that has a single-stranded RNA genome. CVB3 induces myocarditis, and ultimately, dilated cardiomyopathy. A myocarditis variant of CVB3 (CVB3 H3) and its antibody-escape...
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Genetic Variation in the NSP4 Gene of Human Rotavirus Isolated in Seoul

Cho SL, Ahn JH, Kim K, Chung SI, Lim I, Kim W

The nonstructural protein 4 (NSP4) of rotavirus encoded by gene 10, plays an important role in rotavirus pathogenicity. In this study, NSP4 gene sequences of human rotaviruses circulating in Seoul,...
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Alteration in gyrA and parC Gene Associated with Fluoroquinolone Resistance of Enterococcus spp. Isolated from Feces of Chicken

Cho JK, Kim KS, Lee YJ, Park CK, Kwak DM, Kim AR, Kang MS, Kim JW, Kim BH, Ku BK

The purpose of this study was to investigate the fluoroquinolone resistance frequency of Enterococcus spp. from normal chicken feces and to analyse mutations of the gyrA and parC gene associated...
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Prevalence of Salmonella Serovars Isolated from Domestic Residents and Overseas Travelers in Korea, 2004~2005

Kim S, Kim SH, Chun SG, Choi ES, Lee BK

Salmonella is a communicable enteric pathogen commonly found in foodborne diseases. We showed the prevalence of S. enterica serovars from domestic residents and overseas travelers. In 2004-2005 years, Weltevreden, Anatum,...
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Identification of Proteins Induced at Hypoxic and Low pH Conditions in Mycobacterium tuberculosis H37Rv

Lee KS, Park JK, Lim JH, Kim SY, Shin AR, Yang CS, Oh JH, Kwon YM, Song CH, Jo EK, Kim HJ

Mycobacterium tuberculosis likely reside within a granuloma as a dormant state. An area of necrosis forms at the center of lung granulomas. Within this area, the bacteria are deprived of...
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Stabilizing Microtubular Network Facilitates the Intracellular Growth of Orientia tsutsugamushi

Kim MK, Kim MJ, Lim BU, Kang JS

Microtubule network provides many intracellular microbes with an efficient way to move within host cells. Orientia tsutsugamushi move from the cell periphery to the microtubule organizing center (MTOC) by dynein-dependent...
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Epidemiology of Shigellosis in Korea

Lee JC, Jeong YS, Oh JY, Kang HY, Kim KH, Kim J, Lee YC, Cho DT, Seol SY

Shigellosis is an acute diarrheal disease caused by bacteria of the genus Shigella. Following the occurrence of a large outbreak of shigellosis as well as sporadic cases since 1998, shigellosis...
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