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Establishment of Effective Mouse Model of Premature Ovarian Failure Considering Treatment Duration of Anticancer Drugs and Natural Recovery Time

Lee EH, Han SE, Park MJ, Kim HJ, Kim HG, Kim CW, Joo BS, Lee KS

OBJECTIVES: This study was aimed to establish the most effective premature ovarian failure (POF) mouse model using Cyclophosphamide (CTX), busulfan (Bu), and cisplatin considering treatment duration of anticancer drugs and...
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Effects of three-area laser-assisted zona thinning in 8-cell human embryos on pregnancy outcomes in vitro fertilization

Jeong JE, Joo BS, Kim CW, Kim HG, Joo JK, Lee KS

OBJECTIVE: This study conducted a preliminary examination of the effects of three-area laser-assisted zona thinning (LAZT) during the cleavage stage of embryo development on the hatching process in human in...
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Effect of Glucagon-like Peptide-1 on the Differentiation of Adipose-derived Stem Cells into Osteoblasts and Adipocytes

Lee HM, Joo BS, Lee CH, Kim HY, Ock JH, Lee YS

OBJECTIVES: Glucagon-like peptide-1 (GLP-1) is an intestinally secreted hormone and it plays an important role in the regulation of glucose homeostasis. However, the possible role of GLP-1 in the differentiation...
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Effect of laser-assisted multi-point zona thinning on development and hatching of cleavage embryos in mice

Lee YS, Park MJ, Park SH, Koo JS, Moon HS, Joo BS

OBJECTIVE: This study aimed to examine the effect of laser-assisted zona thinning (LAZT) at one or four-points on the blastocyst formation and hatching process in mice with respect to female...
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Effect of Phorbol 12-Myristate 13-Acetate on the Differentiation of Adipose-Derived Stromal Cells from Different Subcutaneous Adipose Tissue Depots

Song JK, Lee CH, Hwang SM, Joo BS, Lee SY, Jung JS

Human adipose-tissue-derived stromal cells (hADSCs) are abundant in adipose tissue and can differentiate into multi-lineage cell types, including adipocytes, osteoblasts, and chondrocytes. In order to define the optimal harvest site...
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Expression of SDF-1alpha and leptin, and their effect on expression of angiogenic factors in mouse ovaries

Park MJ, Park SH, Lee SK, Moon SE, Moon HS, Joo BS

OBJECTIVE: Ovarian angiogenesis plays an important role in folliculogenesis. However, little is known about the expression of angiogenic factors during follicular development according to female age. Stromal cell derived factor-1alpha...
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Alendronate enhances osteoblastic differentiation with increased expression of Id-1 and Id-2 in pre-osteoblast cell line, MC3T3-E1

Park MJ, Joo BS, Lee JE, Kim HJ, Moon SE, Moon HS

OBJECTIVE: Alendronate, a widely used bisphosphonates, acts to inhibit bone resorption by interfering with the activity of osteoclasts. Recently, it has been reported that alendronate also may increase bone proliferation...
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Effects of Leptin on Proliferation, Anabolic and Catabolic Metabolism in Chondrocytes

Lee CK, Ku JH, Cho SH, Hwang TH, Cho HL, Joo BS, An BM, Park MJ, Park JW

  • KMID: 2199047
  • J Korean Orthop Res Soc.
  • 2009 Dec;12(2):68-75.
PURPOSE: Leptin may play an important role in the pathophysiology of osteoarthritis. However, the effect of letpin on the anabolic and catabolic metabolisms in chondrocytes remains unclearly elucidated. Therefore, the...
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The effects of bisphosphonates on differentiation of human amniotic fluid-derived mesenchymal stem cells into osteoblast

An JH, An BM, Choi TY, Kim SG, Moon HS, Joo BS

  • KMID: 1475009
  • Korean J Obstet Gynecol.
  • 2009 Mar;52(3):314-321.
OBJECTIVE: It has been known that amniotic fluid (AF) is rich source of mesenchymal stem cells (MSCs). Bisphosphonates are widely used in clinical treatment of various metabolic bone diseases and...
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The Effect of Zoledronate on the Differentiation of Human Amniotic Fluid-Derived Mesencymal Stem Cells into Adipocytes

Joo BS, An JH, An BM, Choi TY, Song DY, Kim HH, Moon HS

  • KMID: 2300065
  • Korean J Blood Transfus.
  • 2008 Dec;19(3):231-238.
BACKGROUND: Amniotic fluid is a rich source of fetal mesenchymal stem cells (MSCs). However, little is known about whether bisphosphonates affect the differentiation into adipocytes. Therefore, this study was aimed...
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Effect of serum E2 levels on the pregnancy outcome of IVF-ET

Park SH, Joo BS, Song SJ, Kim KS, Moon SE, Moon HS

  • KMID: 2273527
  • Korean J Obstet Gynecol.
  • 2008 Nov;51(11):1309-1315.
OBJECTIVE: To evaluate the effects of serum E2 levels on the day of hCG administration on the pregnancy outcome of IVF-ET after controlled ovarian hyperstimulation (COH). METHODS: Data of 455 cycles...
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Relationship between Osteoarthritis and Leptin Concentrations in Synovial Fluid

Ku JH, Lee CK, Cho HL, Joo BS, An BM, Choi SH, Wang TH

  • KMID: 2199067
  • J Korean Orthop Res Soc.
  • 2008 Oct;11(2):92-99.
PURPOSE: Leptin may play an important role in the pathophysiology of osteoarthritis. This study investigated whether leptin concentration in synovial fluid is related to the radiographic severity of osteoarthritis. MATERIALS AND...
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The Effect of Leptin on the Proliferation of the Endothelial Progenitor Cells from Peripheral Blood

Kim HH, Kim SY, Lee EY, Moon HS, Son HC, Joo BS

  • KMID: 1909657
  • Korean J Blood Transfus.
  • 2007 Dec;18(3):209-218.
BACKGROUND: Leptin has been found to be involved in the regulation of hematopoiesis processes and angiogenesis. Therefore, we investigated the effect of leptin in the proliferation and angiogenesis of peripheral...
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Two cases of spontaneous pregnancy in women with premature ovarian failure: Case report

Lee SK, Joo BS, Moon SE, Kim SK, Koo JS, Moon HS

  • KMID: 1926292
  • Korean J Obstet Gynecol.
  • 2007 Nov;50(11):1558-1562.
Premature ovarian failure (POF) is a syndrome defined as hypergonadotropic hypogonadism associated with amenorrhea, oligomenorrhea or other forms of menstrual irregularity for at least 3 consecutive months before the age...
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Short Coasting of One or Two Days by Withholding Both Gonadotropins and GnRH Agonist Prevents Ovarian Hyperstimulation Syndrome without Compromising the Outcome

Lee SK, Joo BS, Park SH, Lee SK, Kim KS, Moon SE, Moon HS

  • KMID: 2235781
  • Korean J Fertil Steril.
  • 2007 Mar;34(1):49-56.
OBJECTIVE: To evaluate the effect of short coasting, by withdrawing both gonadotropins and GnRH agonist (GnRHa), on the prevention in severe ovarian hyperstimulation syndrome (OHSS) without compromising pregnancy outcome. METHOD: Thirty-seven...
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Improvement of Pregnancy Rate by the Selection of Early Cleavage Embryos to 2-cell Stage in Human IVF

Park SH, Joo BS, Lee SK, Kim KS, Moon HS

  • KMID: 1772286
  • Korean J Fertil Steril.
  • 2005 Mar;32(1):47-53.
OBJECTIVE: Evaluation of embryos using early cleavage to 2-cell stage has been proposed, but a critical time-point for selecting embryos is unclear. The aim of the present study is to...
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Follicular Blood Flow and Follicular Fluid Concentrations of Vascular Endothelial Growth Factor and Nitric Oxide as Prognostic Factors of IVF Outcome

Oh DS, Shin BS, Kim KH, Joo BS, Lee KS

  • KMID: 2272333
  • Korean J Obstet Gynecol.
  • 2004 May;47(5):880-885.
OBJECTIVE: The aim of this study was to investigate the relationship between follicular blood flow and the follicular fluid vascular endothelial growth factor (VEGF), and nitric oxide (NO) concentrations, and...
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A Case of Limb Reduction Defect after Chorionic Villus Sampling at 9 Gestational Weeks

Kim CH, Song SJ, Kim TW, Kim HJ, Moon SE, Kim SK, Joo BS, Moon HS

  • KMID: 1925310
  • Korean J Obstet Gynecol.
  • 2003 Dec;46(12):2520-2523.
Since it has been proposed that chorionic villus sampling could be an etiology of limb reduction defect, the relation between limb defect and chorionic villus sampling remains controversial. We experienced...
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Learning Curve of Laparoscopic Myomectomy

Song SJ, Kim CH, Kim SH, Park EY, Park KS, Moon HS, Kim KS, Joo BS, Kim SG

  • KMID: 1925282
  • Korean J Obstet Gynecol.
  • 2003 Dec;46(12):2345-2351.
OBJECTIVE: To evaluate the effectiveness and feasibility of laparoscopic myomectomy compared to open myomectomy METHODS: A retrospective study of 85 cases of myomectomy was performed. Twenty six cases of open myomectomy...
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Effects of Metformin on Clomiphene-resistant Infertile Women with Polycystic Ovary Syndrome

Moon HS, Joo BS, Park SH, Song SJ, Kim CH, Moon SE, Kim KS

  • KMID: 2076929
  • Korean J Obstet Gynecol.
  • 2003 Oct;46(10):1920-1925.
OBJECTIVE: The aim of this study was to evaluate the efficacy of metformin for ovualtion induction and pregnancy in clomiphene citrate (CC)-resistant women with polycystic ovary syndrome (PCOS). METHODS: From March...
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