Korean J Obstet Gynecol.  2007 Nov;50(11):1558-1562.

Two cases of spontaneous pregnancy in women with premature ovarian failure: Case report

• Lee SK
• Joo BS
• Moon SE
• Kim SK
• Koo JS
• Moon HS

Abstract

Premature ovarian failure (POF) is a syndrome defined as hypergonadotropic hypogonadism associated with amenorrhea, oligomenorrhea or other forms of menstrual irregularity for at least 3 consecutive months before the age of 40. The management of POF is approached by HRT, emotional support and infertility treatment. Women with premature ovarian failure who desire to become pregnant are best treated by assisted reproductive technology with donor oocyte. However, POF has the possibility of a 5-10% spontaneous pregnancy. The physician should recommend the patient to consult with their physician if they have any symptoms of pregnancy or no withdrawal bleeding after HRT. Therefore we report two cases of spontaneous pregnancies in women with premature ovarian failure.

Keyword

Premature ovarian failure; Spontaneous pregnancy

MeSH Terms

Amenorrhea
Female
Hemorrhage
Humans
Hypogonadism
Infertility
Oligomenorrhea
Oocytes
Pregnancy*
Primary Ovarian Insufficiency*
Reproductive Techniques, Assisted
Tissue Donors