Korean J Obstet Gynecol.  1998 Feb;41(2):617-621.

A Case of Premature Ovarian Failure Associated with 46, X, t ( X ; 11 ) in Secondary Amenorrheic Patient

• Nam YS
• Lee SH
• Kwak IP
• Yoon TK
• Cha KY

Abstract

Premature ovarian failure is a condition causing amenorrhea, hypoestrogenism, and elevated gonadotropins in women younger than 40 years. A karytype should be performed as part of basic laboratory evaluation for all patients with premature ovarian failure and prodromal premature ovarian failure. Although it has been suggested that the karyotype be omitted in patients who are either parous or older than 35 years, neither age nor parity rules out a chromosomal abnormality. We have experienced a case of premature ovarian failure in secondary amenorrheic patient showing chromosomal abnormality. So we report this case with a brief review of literatures.

Keyword

Premature ovarian failure; Secondary amenorrhea; Chromosomal abnormality

MeSH Terms

Amenorrhea
Chromosome Aberrations
Female
Gonadotropins
Humans
Karyotype
Parity
Primary Ovarian Insufficiency*
Gonadotropins