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Metabolic syndrome: prevalence and risk factors in Korean gout patients

Jung JH, Song GG, Ji JD, Lee YH, Kim JH, Seo YH, Choi SJ

BACKGROUND/AIMS: We performed this study to investigate associations between metabolic syndrome, chronic kidney disease (CKD), and gout. METHODS: We reviewed the medical records of 151 patients with gout at the Department...
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The Role of Bile Acid Receptors in Chronic Inflammatory Diseases

Park R, Ji JD

With recent developments, biologic therapies has shown superior efficacy for rheumatic diseases compared with preexisting pharmacologic therapies, which are associated with high costs, non-response in certain patient groups, and severe...
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Panenteritis as an Initial Presentation of Systemic Lupus Erythematosus

Lee HA, Shim HG, Seo YH, Choi SJ, Lee BJ, Lee YH, Ji JD, Kim JH, Song GG

Lupus enteritis is a rare, severe complication of systemic lupus erythematosus (SLE), needing prompt diagnosis and proper management. However, SLE rarely presents as lupus enteritis at the time of initial...
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A Case of Non-Hodgkin's Lymphoma of the Ocular Adnexa and Lung in a 17-year-old with Primary Sjogren's Syndrome

Kim SH, Lee HA, Park SW, Lee KW, Seo YH, Kim JH, Choi SJ, Lee YH, Ji JD, Song GG

Sjogren's syndrome (SS) is a chronic autoimmune disorder characterized by lymphocyte-mediated destruction of exocrine glands, which produces classical symptoms of dry eyes and dry mouth. Aside from the clinical manifestations...
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Gene Expression Profile in Patients with Axial Spondyloarthritis: Meta-analysis of Publicly Accessible Microarray Datasets

Park R, Kim TH, Ji JD

OBJECTIVE: To identify a gene expression signature in axial spondyloarthritis/ankylosing spondylitis (SpA/AS) and genomic pathways likely to be involved in pathogenesis of SpA/AS patients. METHODS: Four publicly accessible microarray studies from...
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A Case of Massive Pulmonary Embolism in Systemic Lupus Erythematosus without Antiphospholipid Antibody

Jung JH, Lee MG, Sim JS, Kim TH, Oh HK, Ji JD, Lee YH

Patients with systemic lupus erythematosus (SLE) are at an increased risk of developing thromboses with antiphospholipid antibodies (aPL). The presence of aPL is related to an increased risk of thrombotic...
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Clinical Significance of High Erythrocyte Sedimentation Rates in Rheumatoid Arthritis Patients Fulfilled the Remission Criteria

Ji JD

No abstract available.
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Acute Precursor T Cell Lymphoblastic Leukemia Associated with Behcet's Disease: A Case Report

Kim JW, Pyo JH, Kim KJ, Kim H, Jeoung Y, Ji JD, Lee YH

Behcet's disease is an inflammatory disorder characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. A few cases of hematologic disease in patients with Behcet's disease have...
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Leflunomide-induced Toxic Epidermal Necrolysis in a Patient with Rheumatoid Arthritis

Je JH, Lee HJ, Na YJ, Seo JH, Seo YH, Kim JH, Choi SJ, Lee YH, Ji JD, Song GG

Leflunomide was licensed for the treatment of rheumatoid arthritis in 1998 and has been available in Korea since 2003. Allergic cutaneous reactions (rash, purpura) are common (
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A Case of Sweet's Syndrome Associated with Rheumatoid Arthritis Involving Multiple Skin Lesions

Seo YH, Lee YH, Ji JD, Song GG, Yoo SH, Ahn J, Choi SJ

Sweet's syndrome is a neutrophilic dermatoses characterized by the abrupt onset of fever, leukocytosis and skin lesions that are infiltrated by neutrophils. Most skin lesions are in the form of...
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A Case of Wegener's Granulomatosis with Central Nervous System Involvement Mimicking Lung Cancer with Brain Metastasis

Park JH, Lee YH, Ji JD, Song GG, Lee SW, Yoo SH, Ryu JY, Kim HR, Kang KH, Kang SH, Kim SW, Choi SJ

Wegener's granulomatosis (WG) classically consists of necrotizing granulomatous inflammation of the upper and/or lower respiratory tract, necrotizing glomerulonephritis, and an autoimmune necrotizing systemic vasculitis affecting predominantly small vessels. We report...
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A Case of Behcet's Disease Complicated with a Pulmonary Artery Aneurysm and Deep Vein Thrombosis, Separately

Lee JM, Ahn J, Hwang YJ, Kim SH, Lee JS, Choi SJ, Lee YH, Ji JD, Song GG

Behcet'sdisease is a chronic inflammatory disease characterized by oral ulcers, genital ulcers, uveitis, and skin lesions. Furthermore, Behcet's disease can manifest as vascular lesions, such as, those of vasculitis, venous...
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A Case of Refractory SAPHO Syndrome Treated with Etanercept

Kim YJ, Bae SI, Choi SJ, Lee YH, Ji JD, Song GG

SAPHO syndrome, which has different skin changes and osteoarticular inflammation, is an acronym that stands for synovitis, acne, pustulosis, hyperostosis, and osteitis. Treatment of SAPHO syndrome includes non-steroidal anti-inflammatory drugs...
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Study of the Gene Expressions in Rheumatoid Arthritis Synovial Macrophages Using Network Analysis

Ji JD, Kim TH, Lee B, Choi SJ, Lee YH, Song GG

  • KMID: 2391936
  • J Rheum Dis.
  • 2011 Jun;18(2):101-109.
OBJECTIVE: We wanted to investigate the mechanisms that could account for the pathogenesis of rheumatoid arthritis, so we examined the different expressions of the genes in rheumatoid arthritis (RA) synovial...
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A Case of Secondary Antiphospholipid Antibody Syndrome with Thyroid Cancer

Kang SH, Choi SJ, Lee YH, Ji JD, Song GG

Antiphospholipid antibody syndrome (APS) is defined as the presence of lupus anticoagulant antibody or anticardiolipin antibody with vascular thrombosis or pregnancy complications. APS can be associated with autoimmune disease or...
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Expression of Osteoclastogenesis-related Genes in Rheumatoid Arthritis Synovial Macrophages

Ji JD, Kim TH, Lee B, Choi SJ, Lee YH, Song GG

OBJECTIVE: To examine the mechanism for the inhibited differentiation of osteoclasts in rheumatoid arthritis synovial CD14+ osteoclast precursors, the different expressions of the osteoclastogenesis-related genes in rheumatoid arthritis (RA) synovial...
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Integrated Analysis of MicroRNA and mRNA Expression Profiles in Rheumatoid Arthritis Synovial Monocytes

Ji JD, Kim TH, Lee B, Na KS, Choi SJ, Lee YH, Song GG

OBJECTIVE: MicroRNAs (miRNAs) play important roles in many biological processes and recent studies have provided growing evidences that miRNA dysregulation might play important roles in the pathogenesis of rheumatoid arthritis...
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The Role of MAPK Signaling of 1,25(OH)2D3-induced CYP24 Expression in Activated Human Macrophages

Ji JD, Lee BN, Kim TH, Woo JH, Choi SJ, Lee YH, Song GG

  • KMID: 2334913
  • J Korean Rheum Assoc.
  • 2010 Sep;17(3):254-262.
OBJECTIVE: Several important roles of 1,25(OH)2D3 have been recognized in the immune system. The availability of 1,25(OH)2D3 at the cellular level is significantly influenced by the relative abundance of enzymes...
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Rheumatoid Arthritis and microRNA

Ji JD, Kim TH

  • KMID: 2334910
  • J Korean Rheum Assoc.
  • 2010 Sep;17(3):230-237.
MicroRNAs (miRNAs) are small, single-stranded, non-coding RNA molecules of 20~22 nucleotides, which are involved in many biologic functions such as development, cell proliferation, differentiation, and apoptosis. In addition to these...
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A New Onset of Systemic Lupus Erythematosus Developed After Bee Venom Therapy

Rho YH, Woo JH, Choi SJ, Lee YH, Ji JD, Song GG

Lupus is a systemic autoimmune disease of an unknown origin, and systemic lupus erythematosus (SLE) can be triggered by numerous stimuli. Bee venom therapy is an alternative therapy that is...
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