J Korean Rheum Assoc.  2008 Mar;15(1):27-38. 10.4078/jkra.2008.15.1.27.

Diagnostic Accuracies of Anti-cyclic Citrullinated Peptide Antibody and Rheumatoid Factor in Korean Patients with Rheumatoid Arthritis: A Meta-analysis

• Lee YH
• Woo JH
• Choi SJ
• Ji JD
• Song GG

• KMID: 1324506
• DOI: http://doi.org/10.4078/jkra.2008.15.1.27

Abstract

No Abstract available.

Keyword

Rheumatoid arthritis; Anti-CCP; RF; Meta-analysis

Figure

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  Fig. 1. Flow diagram of study selection. Articles reported the diagnostic value of anti-CCP antibody and RF testings for RA.

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  Fig. 2. Sensitivity (A) and specificity (B) estimates for anti-CCP antibody for the diagnosis of RA. Circles and lines represent point estimates and 95% CIs, respectively. Circle areas represent relative study sizes. 1 means 100% in sensitivity and specificity.

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  Fig. 3. SROC curves for anti-CCP antibody (A) and for RF (B) for the diagnosis of RA Solid circles represent individual studies included in this meta-analysis. The curve shown is a regression line that summarizes overall diagnostic accuracy. SE (AUC), standard error of AUC, Q∗, an index defined by the point on the SROC curve where the sensitivity and specificity are equal; SE (Q∗), Q∗ index standard error.

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  Fig. 4. SROC curves for either anti-CCP or RF (A) and both anti-CCP and RF positivity (B) for the diagnosis of RA Solid circles represent individual studies included in this meta-analysis. The curve shown is a regression line that summarizes overall diagnostic accuracy. SE (AUC), standard error of AUC, Q∗, an index defined by the point on the SROC curve where the sensitivity and specificity are equal; SE (Q∗), Q∗ index standard error.

Reference

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